The Voltaren tablets: instructions for use, price 50 mg, reviews, analogs
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Voltaren tablets instructions for use

ATX code M01AB05

Pharmacotherapeutic group : NSAIDs.

Dosage form : tablets for internal use.

Form of issue : round biconvex tablets of yellow color with a facet, on one side impression CG, on the other - BZ. They are covered with an enteric coating. Contouring package, cardboard box.

Pharmacological properties

Anti-inflammatory, analgesic, antipyretic.


Active substances :

  • sodium diclofenac.

Auxiliary components :

  • microcrystalline cellulose;
  • magnesium stearate;
  • hydroxypropylmethylcellulose;
  • oxystearate;
  • silicon dioxide colloidal;
  • polyvinylpyrrolidone K30;
  • titanium dioxide;
  • iron oxide yellow;
  • iron oxide red;
  • corn starch;
  • talc;
  • emulsion silicone;
  • macrogol 8000;
  • copolymer of esters and acids (methacrylic, polyacrylic);
  • sodium carboxymethyl starch;
  • glyceryl polyethylene glycol.


Actively acting component of the drug is a substance of non-steroidal nature, which has a pronounced antipyretic, anti-inflammatory and analgesic effect. The main mechanism is the inhibition of the biological synthesis of prostaglandins, which play a leading role in the genesis of pain, inflammation and fever. This preparation does not exert a suppressive effect on the biosynthesis of proteoglycans of the cartilaginous tissue.

In the treatment of pathologies of rheumatic nature, the severity of pain, morning stiffness and swelling of articular joints are significantly reduced, and their functioning is noted to improve.

With inflammatory phenomena of post-operation or post-traumatic origin, the drug also has an analgesic effect. At the same time, he is able to eliminate pain and reduce the severity of blood loss in primary dysmenorrhea. Cures migraine attacks.


Tablets, covered with an enteric-coated shell, after ingestion are completely absorbed in the intestine. In the event that the medication is taken during or immediately after a meal, its slow passage through the stomach is noted, but the amount of the active ingredient is not changed.

After a single dose of 50 mg of Voltaren, the maximum concentration of diclofenac in the plasma (1.5 μg / ml) is observed after 2 hours. The degree of absorption of the drug depends on the size of the dose. With strict adherence to the intervals between tablets, cumulation is not observed.

The connection with plasma proteins is 99.7% (99.4% - with albumin). In synovial fluid, diclofenac reaches its maximum concentration 2-4 hours later than in plasma. The half-life of the drug in synovia is 3-6 hours.

Metabolism of diclofenac is carried out in the liver, with the formation of phenolic metabolites, which turn into glucuronide conjugates.

The total plasma clearance of the active ingredient is 263 plus or minus 56 ml / min. The final half-life is 1-2 hours. T 1/2 metabolites - 1-3 hours. About 60% of the drug is excreted by the kidneys along with the urine, the rest - along with the feces.

Indications for use

  • Inflammatory and degenerative-dystrophic pathologies of the musculoskeletal system (osteoarthritis, rheumatoid and juvenile arthritis, spondyloarthropathies, gouty arthritis, tenosynovitis, chronic arthritis, bursitis, etc.);
  • Post-traumatic or post-operative pain syndrome (in orthopedics, dentistry);
  • Pain in the spine (radiculitis, ossalgia, sciatica, etc.);
  • Algodismenorea;
  • Infectious and inflammatory pathologies of ENT organs, accompanied by severe pain syndrome (otitis media, tonsillitis , pharyngitis );
  • Adnexitis and other inflammatory diseases of the small pelvis

Voltaren, tablets - this is a symptomatic drug that eliminates clinical manifestations of the disease, but does not affect its progression.


  • Stomach ulcer and 12-intestine (exacerbation, perforation phase, ulcerous bleeding);
  • Ulcerative colitis, Crohn's disease (exacerbation phase);
  • Severe degree of renal failure;
  • Heart failure (decompensation stage);
  • Severe form of hepatic insufficiency;
  • Attacks of bronchial asthma, rhinitis, urticaria , provoked by the use of acetylsalicylic acid;
  • Conditions accompanied by a risk of bleeding;
  • Hyperkalemia;
  • Aortocoronary bypass grafting (pre- and postoperative period);
  • Individual intolerance to the components of the drug;
  • III trimester of pregnancy and lactation;
  • Children up to 14 years.

Dosing and Administration

The dosage of the drug is determined individually. If possible, the drug is administered in a minimally effective dose, with the shortest course of treatment.

Tablets should be taken after meals, swallowing whole and with water.

The initial recommended dose for adults is 100-150 mg per day. With mild forms of pathology, 75-100 mg per day is sufficient.

With primary dysmenorrhea, the daily dose is 50-150 mg. The initial - 50-100 mg / day, if necessary, increases to 150 mg. The drug should be used when the first symptoms occur. Depending on the condition of the patient, treatment can be performed for several days.

Side effect

On the part of the digestive system : nausea, vomiting, diarrhea, abdominal pain, decreased appetite, anorexia, dyspepsia.

From the sense organs : visual disturbances (rarely), hearing impairment, vertigo.

From the nervous system : dizziness, headaches, flavors. Rarely tremor of extremities, memory disorders, seizures , acute disturbance of cerebral circulation.

On the part of the respiratory system : pneumonitis, asthma.

From the cardiovascular system : arterial hypertension, hot flashes, vasculitis, heart failure, myocardial infarction.

From the urinary system : proteinuria, hematuria, acute renal failure, papillary necrosis, nephrotic syndrome.

From the skin: hyperemia, generalized rash, itching, dermatosis, alopecia.

Other disorders : peripheral and generalized edema, edema of the face.

Drug Interactions

Diclofenac is able to increase the concentration in the blood plasma of digoxin and lithium.

When used simultaneously with potent inhibitors of CYP2C9 in the serum, the concentration of diclofenac increases, and the systemic effect of the drug is also increased, due to the inhibition of its metabolism.

NSAIDs reduce the hypotensive effect of diuretics and antihypertensive drugs.

With the simultaneous use of systemic action with other NSAIDs, the frequency of adverse reactions from the digestive tract increases.

When interacting with selective serotonin reuptake inhibitors, the risk of developing gastric bleeding increases significantly.

Simultaneous use with methotrexate increases the concentration and toxic effects of the latter.

Enhances nephrotoxicity of cyclosporins.

Increases the systemic effect of phenitonin.


  • Arterial hypotension;
  • Digestive disorders;
  • Renal failure;
  • Convulsions.

Leave conditions

Refers to prescription drugs.

Storage conditions

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 30 ° C.

Shelf life

Shelf life of the drug is 5 years from the date of issue. After the expiration date indicated on the package, the drug should not be used.

Voltaren tablets price

Voltaren tablets 50 mg, 20 pieces - 260 - 300 rubles.

Voltaren tablets analogues

  • Diclofenac sandoz;
  • Diclonat P;
  • Naklofen;
  • Dicclore.
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