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Byzanna instructions for use

Vizanna tablets are progestogenic and antiandrogenic drugs. This drug is used to treat endometriosis in women in gynecological practice.

Release form and composition

The drug Vizanna comes in the form of tablets for oral administration, they have a white or light yellow color and a round shape. The main active ingredient of the drug is dienogest, which is contained in the amount of 2 mg in 1 tablet. Also included in the tablet are auxiliary components, which include:

  • Lactose monohydrate.
  • Microcrystalline cellulose.
  • Potato starch.
  • Povidone K25.
  • Crospovidone.
  • Talc.
  • Magnesium stearate.

The tablets are packaged in a blister in the amount of 28 pieces. The carton pack contains one blister and instructions for use of the drug.

pharmachologic effect

The main active ingredient of the Vizanna Dienogest tablets is a chemical derivative of Nortestosterone. It is able to bind to the progesterone receptors of the uterus, although it has a small affinity directly for the progesterone molecule (the affinity of the molecules of dienogest and progesterone is about 10%). Due to this binding, dienogest has a powerful progestogen effect, which is manifested in several therapeutic effects:

  • Suppression of the trophic effects of estrogen against foci of endometriosis (unusual localization of endometrial cells outside the inner layer of the uterus).
  • Decreased production of estrogen in the ovaries and its concentration in the blood.
  • Atrophy of endometrial foci - reducing their size and cell mass.

Vizann tablets do not affect the concentration of other hormones of the body, in particular the sex hormones of the adrenal cortex, glucocorticoids and aldosterone. Due to these effects, the progestogenic and antiandrogenic effects of the drug are realized.

After taking the tablet Vizanna inside, the main active substance without residue is absorbed into the blood, where it reaches the maximum concentration within 1.5 hours after administration. Dienogest is distributed in all tissues of the body, it is metabolized mainly in the liver, and the decay products are excreted by the kidneys in the urine. The half-life (the time of elimination from the body of half of the entire dose of the drug taken) is on average 9-10 hours.

Indications for use

The main indication for the use of Vizann tablets is endometriosis, a pathology of the female reproductive system in which ectopia (unusual localization) of the inner layer of the uterine wall (endometrium) develops.

Contraindications

Acceptance of Vizann tablets is contraindicated in the case of several pathological and physiological conditions of the body, which include:

  • Individual intolerance or hypersensitivity to the active substance or auxiliary components of the drug.
  • Thrombophlebitis is a pathology of the venous vessels, accompanied by the formation of blood clots in their lumen and leading to a high risk of developing thromboembolism (migration of a blood clot in the vascular bed), the presence of thromboembolism at the time of using Vizann tablets.
  • Atherosclerotic vascular lesion - the deposition of cholesterol in the walls of the arteries with the formation of atherosclerotic plaque. The drug is contraindicated in any form of atherosclerosis - ischemic heart disease (with or without angina), myocardial infarction, cerebral atherosclerosis, cerebral stroke, vascular damage to the kidneys.
  • Diabetes mellitus in the stage of subcompensation and decompensation in the presence of various vascular complications, including angiopathy of the retina and the development of diabetic foot.
  • Pathology of the liver, which is accompanied by a decrease in its functional activity (viral, toxic hepatitis, cirrhosis of the liver , oncological process at the time of treatment or you are past).
  • Vaginal bleeding of unknown origin.
  • Disruption of the functional activity of the digestive system, accompanied by intolerance to galactose, including malabsorption syndrome and congenital insufficiency of certain digestive enzymes.
  • Stagnation of bile in the gallbladder or biliary tract (cholestasis) with the development of cholestatic jaundice.
  • Children's age up to 18 years.

Before starting the use of Vizann tablets, you must make sure that there are no contraindications.


Dosage and administration

Byzanne tablets are taken orally completely regardless of the meal, they are washed down with a sufficient amount of liquid. Take 1 tablet per day, preferably at the same time. The treatment regimen for endometriosis using Vizann tablets involves taking the drug every day, regardless of the day of the menstrual cycle. Begin treatment also regardless of the cycle. The course of therapy is usually 6 months. If you accidentally skip a dose, you need to take the next pill as early as possible. Further reception continues in the same way and at the same time as before the pass. If vomiting occurs within 15–20 minutes after taking the drug, the pill must be taken again.

Side effects

Taking the Vizann tablets can lead to the development of side effects from various organs and systems, these include:

  • The digestive system - nausea, vomiting, abdominal pain (including the lower abdomen), a feeling of abdominal distention, flatulence (increased gas formation in the intestinal lumen), unstable stools (constipation and diarrhea).
  • The nervous system - the emergence of feelings of anxiety, a tendency to lower mood and depression, intermittent insomnia at night and daytime sleepiness, headache (up to the development of a migraine), emotional instability with bouts of irritability, an imbalance of peripheral nerves, decreased libido (sexual desire for the opposite sex).
  • Sense organs - a feeling of dryness in the eyes, noise or ringing in the ears.
  • Metabolism and hormonal balance - weight gain, hirsutism (increased hairiness) or alopecia (hair loss).
  • Skin and subcutaneous tissue - the development of acne (acne), hyperhidrosis (excessive sweating), dermatitis (skin inflammation), increased skin photosensitivity, a violation of its pigmentation (concentration of melanin, which gives color to the skin), the appearance of dandruff.
  • Respiratory system - the appearance of shortness of breath.
  • Cardiovascular system - the development of arrhythmias (arrhythmia or heart rate), a decrease in systemic blood pressure (arterial hypotension).
  • Musculoskeletal system - pain in the bones, back, upper and lower extremities, spasms striated muscles.
  • The urinary system is a variety of infectious inflammatory processes in the kidneys, ureters, or bladder.
  • The reproductive system and mammary glands - discomfort in the mammary glands (increase in size, heaviness, feeling of distention, recurrent pain, fibrous or cystic mastopathy), ovarian cyst , candidiasis, vaginal dryness, uterine or vaginal bleeding of various intensity, amenorrhea (no menstruation) , pain in the pelvis.

The appearance of symptoms of adverse reactions of the body to the drug is the reason for its cancellation.

special instructions

Before you start taking the Vizann tablets, you should carefully read the instructions. There are several specific indications regarding the use of the drug, which include:

  • Before the use of the drug for the treatment of endometriosis, it is necessary to exclude pregnancy, since in the case of its presence the therapy of this pathology is not carried out.
  • While taking the pills, you can not simultaneously apply the methods of oral contraception using hormonal drugs.
  • With caution, Vizann tablets are used in women with a tendency to depression, an ectopic pregnancy in the past, impaired lipid (fat) metabolism, and the presence of thromboembolic processes in the past, including thrombophlebitis. In these cases, the drug is prescribed only after a thorough analysis of the risk / benefit ratio from its use.
  • The drug can interact with various drugs, so if they are taken in parallel, the doctor should be warned about this.
  • The use of Vizanna tablets for nursing women is not recommended, since the active substance passes into breast milk, which can affect the condition of the infant.
  • The drug does not affect the speed of psychomotor reactions and concentration.

Pharmacies Vizin tablets are released on prescription. It is not recommended to take the drug yourself or use it on the advice of third parties.


Overdose

In case of exceeding the recommended therapeutic dose of the drug, symptoms of side effects usually develop. Gastric and intestinal lavage and symptomatic therapy is performed to treat overdose.

Byzanna counterparts

Similar to the active substance and therapeutic effect is the drug Dienogest.

Terms and conditions of storage

Shelf life of the drug is 2 years from the date of its manufacture. The Vizann tablets must be stored in a dark place inaccessible to children at an air temperature not higher than + 30 ° C.

Byzanna price

The average cost of Vizanna tablets in pharmacies in Moscow is 2900-3100 rubles.

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Reviews of the drug Byzanna:

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  • | Olga | 6th October 2015

    She took Byzanna, menstruation was gone. When will the monthly come after canceling the reception of Vizanna?

  • | Anna | 6th October 2015

    Olga, this is a hormonal drug, because such side effects are possible. Monthly should begin in the first 1-3 cycles.

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