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Vimovo instruction manual

Vimovo is a unique complex medicinal product for the treatment of abnormalities of the oporno - motor apparatus, containing, in addition to the nonsteroidal anti - inflammatory component, a drug that suppresses the secretion of gastric juice.

Form of release and composition:

the preparation is released in the form of oval, enteric-coated tablets of yellow color. On one side of the tablets there is an inscription in black font "500/20".

One tablet contains:

  • 500 mg naproxen;
  • 22.3 mg of esomeprazole magnesium trihydrate, which corresponds to

20 mg of esomeprazole.

Auxiliary components: povidone K90, triethyl citrate, croscarmellose sodium, polysorbate 80, glycerin monostearate, silicon colloidal dioxide, methyl parahydroxybenzoate, magnesium stearate, propyl parahydroxybenzoate, hypromellose, methacrylic acid and ethyl acrylate copolymer (1: 1), macrogol 8000, titanium dioxide, suspension 30% , polydextrose, hypromellose 6 mPas, hypromellose 50 mPas, carnauba wax, iron oxide yellow, black ink (Opacode black).

The tablets are packed in 6, 10, 30 or 60 pieces in a plastic bottle with a screw cap with the control of the first opening. The bottle is in a cardboard box with instructions for medical use.

Mechanism of action:

A special form of production of tablets allows you to consistently deliver the components of the drug in the necessary parts of the gastrointestinal tract. The Vimovo tablet shell contains immediate-release esomeprazole magnesium, which causes the substance to act almost immediately after it enters the stomach.

In the core of the tablet is naproxen, hidden under an enteric-soluble shell with sustained release. As a result, naproxen begins to be absorbed into the bloodstream only in the small intestine. The special release of Vimovo's active components minimizes the adverse effects of naproxen on the gastric mucosa.

Naproxen is a representative of a group of non-steroidal anti-inflammatory, analgesic and antipyretic agents. The properties of this Vimovo component allow to reduce or completely get rid of joint and muscle pain, to reduce the manifestation of the inflammatory process. Naproxen significantly reduces the morning stiffness and swelling of the joints, contributes to an increase in the volume of movements.

Esomeprazole is a proton pump inhibitor. The proton pump in the human body is responsible for the production of hydrochloric acid in the stomach. The use of drugs from the group of non-steroidal anti-inflammatory drugs, which includes naproxen, adversely affects the internal surface of the stomach, causing irritation, erosion, gastritis and ulcers. Esomeprazole blocks the production of hydrochloric acid, which reduces the irritant effect on the mucosa of the gastrointestinal tract.

Indications for use:

Vimovo is used to relieve pain in people with an increased risk of developing gastric ulcer and duodenal ulcer with the following pathologies of the musculoskeletal system:


  • individual intolerance to esomeprazole, naproxen, benzimidazole derivatives, as well as other components that make up the drug;
  • children and adolescents under 18;
  • bronchial asthma, urticaria ;
  • tendency to bleeding;
  • excess content of total potassium in the body (hyperkalemia);
  • pregnancy and the period of breastfeeding;
  • exacerbation of peptic ulcer of the stomach, duodenum;
  • inflammatory bowel disease in the acute phase;
  • uncontrolled heart failure;
  • severe hepatic and renal insufficiency;
  • period after coronary artery bypass grafting;
  • acute periods of liver disease;
  • simultaneous use with atazanavir and nelfinavir is unacceptable.

Dosing and Administration

Vimovo should be taken 30 minutes before meals twice a day, in the morning and in the evening, with plenty of water. The tablet can not be broken, crushed or chewed. The use of the drug after eating slows down its absorption by the body.

Patients with impaired liver or kidney function should be under medical supervision

Side effects

  • allergic reactions;
  • sleep disturbance;
  • increased frequency of heart attacks;
  • disruption of normal function of the stomach and intestines, nausea, vomiting;
  • dizziness and headaches;
  • impairment of hearing and sight;
  • pain in the abdominal cavity;
  • diarrhea, constipation;
  • depression;
  • abnormal bulging of the intestinal wall.

Special instructions:

Particular care requires the use of the drug in heart failure, stable hypertension, peripheral arterial disease, cerebral circulation impairment. Simultaneous use of Vimovo with corticosteroids for internal use, acetylsalicylic acid, diuretics increases the risk of exacerbation of cardiovascular pathologies.

Predisposition to diseases of the digestive system increases the likelihood of developing negative side effects. In elderly patients, the risk of complications after using the drug is also increased.

Reducing the level of acidity can have an adverse effect on the barrier function of the stomach. The probability of intestinal infections increases. In addition, a prolonged change in the pH of the stomach to the neutral side can lead to the growth of benign tumors.

Since Vimovo can cause dizziness, visual impairment and hearing, special care should be taken to use the drug in persons whose activities are related to the management of transport and work requiring increased attention.


Elevated doses of Vimovo can cause drowsiness, dizziness, pain in the epigastric region, gastric bleeding, stopping breathing, vomiting. Specific antidote does not exist for the treatment of drug overdose. In case of poisoning, it is necessary to induce vomiting, take a laxative and enterosorbents.


Today there are no complete structural analogues of Vimovo. Analogues of the drug according to the mechanism of action include Nalgezin, Sanaprox, Naproxen Acry, Aliv, Apranaks, Pronaxen.

Terms and conditions of storage

The shelf life of Vimovo tablets is 2 years at a temperature of up to 30 ° C.

Keep the drug in a dry and inaccessible place for children.

The use of the medicinal product after the expiration of its useful life is unacceptable.

Conditions of leave from pharmacies

The drug is released on prescription.

Vimovo price

Currently, the drug is not available in pharmacies in Moscow.

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