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Vimovo instructions for use

Vimovo is a unique complex medicine for the treatment of pathologies of the oporno-musculoskeletal system, which contains, in addition to the non-steroidal anti-inflammatory component, a drug that suppresses the secretion of gastric juice.

Release form and composition:

the drug is produced in the form of oval enteric-coated tablets of yellow color. On one of the sides of the tablets inscribed in black font "500/20".

One tablet contains:

  • 500 mg naproxen;
  • 22.3 mg of esomeprazole magnesium trihydrate, which corresponds to

20 mg of esomeprazole.

Auxiliary components: povidone k90, triethyl citrate , polydextrose, hypromellose 6 mPas, hypromellose 50 mPas, carnauba wax, iron oxide yellow, black ink (Opacode black).

Tablets packed in 6, 10, 30 or 60 pieces in a plastic bottle with a screw cap with the control of the first opening. The bottle is in a carton with instructions for medical use.

Mechanism of action:

The special form of the manufacture of tablets allows you to consistently deliver the components of the drug in the necessary sections of the gastrointestinal tract. The shell of Vimovo tablets contains an immediate release of Esomeprazole Magnesium, due to which the substance exerts its effect almost immediately after entering the stomach.

At the core of the pill is naproxen, hidden under the enteric shell with a sustained release. As a result, naproxen begins to be absorbed into the bloodstream only in the small intestine. The special release of the active components of Vimovo minimizes the negative effects of naproxen on the gastric mucosa.

Naproxen is a representative of a group of nonsteroidal anti-inflammatory, analgesic and antipyretic drugs. The properties of this component Vimovo allow you to reduce or completely get rid of pain in the joints and muscles, reduce the manifestation of the inflammatory process. Naproxen significantly reduces morning stiffness and swelling of joints, increases the range of motion.

Esomeprazole refers to proton pump inhibitors. The proton pump in the human body is responsible for the production of hydrochloric acid in the stomach. The use of drugs from the group of nonsteroidal anti-inflammatory drugs, which include naproxen, adversely affects the inner surface of the stomach, causing irritation, erosion, gastritis and ulcers. Esomeprazole blocks the production of hydrochloric acid, which reduces irritation of the gastrointestinal mucosa.

Indications for use:

Vimovo is used to relieve pain in persons with an increased risk of developing gastric ulcer and duodenal ulcer with the following pathologies of the musculoskeletal system:


  • individual intolerance of esomeprazole, naproxen, benzimidazole derivatives, as well as other components included in the preparation;
  • children and adolescents up to 18 years;
  • bronchial asthma, urticaria ;
  • bleeding tendency;
  • excessive content of total potassium in the body (hyperkalemia);
  • pregnancy and breastfeeding;
  • exacerbation of gastric ulcer, duodenal ulcer;
  • inflammatory bowel disease in the acute phase;
  • uncontrolled heart failure;
  • severe hepatic and renal failure;
  • the period after coronary artery bypass surgery;
  • acute periods of liver disease;
  • simultaneous use with atazanavir and nelfinavir is unacceptable.

Dosing and Administration

Vimovo should be taken 30 minutes before meals twice a day, in the morning and in the evening, drinking plenty of water. The tablet can not be crushed, crushed or chewed. The use of the drug after a meal slows down its absorption by the body.

Patients with impaired liver or kidney function must be under medical supervision.

Side effects

  • allergic reactions;
  • sleep disturbance;
  • increased number of heart beats;
  • violation of the normal function of the stomach and intestines, nausea, vomiting;
  • dizziness and headaches;
  • impaired hearing and vision;
  • abdominal pain;
  • diarrhea, constipation;
  • depression;
  • abnormal protrusion of the intestinal wall.

Special instructions:

Particular caution requires the use of the drug in heart failure, stable hypertension, peripheral artery disease, cerebrovascular accident. Simultaneous use of Vimovo with corticosteroids for internal use, acetylsalicylic acid, diuretic drugs increases the risk of exacerbation of cardiovascular pathologies.

Predisposition to diseases of the digestive system increases the likelihood of negative side effects. Elderly patients also have an increased risk of complications after using the drug.

Reduced acidity can have an adverse effect on the barrier function of the stomach. Increases the likelihood of intestinal infections. In addition, a long-term change in the pH of the stomach in a neutral direction can cause the growth of benign tumors.

Since Vimovo can cause dizziness, impaired vision and hearing, it is necessary to take particular care with the use of the drug in people whose activities are related to the management of transport and work requiring increased attention.


Increased doses of Vimovo can provoke drowsiness, dizziness, pain in the epigastric region, gastric bleeding, respiratory arrest, vomiting. Specific antidote does not exist for the treatment of drug overdose. In case of poisoning, it is necessary to induce vomiting, take laxatives and enterosorbents.


Today, full structural analogs of Vimovo do not exist. By analogy of the drug on the mechanism of action can be attributed Nagezin, Sanaproks, Naproxen Acri, Alive, Apranax, Pronaxen.

Terms and conditions of storage

The shelf life of tablets Vimovo 2 years at temperatures up to 30 0 C.

Store the drug should be in a dry and out of reach of children.

Use of the drug after its expiration date is unacceptable.

Pharmacy sales terms

The drug is available on prescription.

Vimovo price

At the moment, the drug is not in pharmacies in Moscow.

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