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Vilprafen Solyutab: instructions for use

The drug belongs to the macrolide antibiotics group. If to apply Vilprafen solyutab in the recommended dosages, then there is a bacteriostatic effect on a large range of microorganisms. In high concentrations has a bactericidal effect. Shows activity against gram-positive and gram-negative bacteria. It does not affect enterobacteria, therefore its effect on the microflora of the gastrointestinal tract will be minimal. Resistance to the active component is quite rare.

Release form and composition

Josamycin - the main active ingredient of the drug. Vilprafen Solyutab produced by the manufacturer in pill form. Tablets are white or mild yellowish. “IOSA” is inscribed on their surface with a line on one side and “1000” on the other. Pill shape - oblong. The taste is sweet. It has a strawberry flavor.

In 1 tablet, the content of the active ingredient josamine reaches 1000 mg. Additional substances are microcrystalline cellulose, aspartame, strawberry flavoring, sodium dusse, magnesium stearate, hyprolose and colloidal silicon dioxide.

Indications for use

Vilprafen solutiub can be used in many diseases of infectious - inflammatory nature. These include:

  • whooping cough;
  • dacryocystitis, blepharitis and other ophthalmologic diseases;
  • scarlet fever ;
  • anthrax;
  • erysipelas;
  • bronchitis. Different types of pneumonia;
  • infections of ENT - organs ( tonsillitis , sinusitis, otitis, pharyngitis and many others);
  • diseases of the mouth;
  • diphtheria ;
  • psittacosis;
  • lymphogranuloma venereal;
  • gastrointestinal tract diseases provoked by Helicobacter pylori;
  • diseases of the genitourinary system;
  • sexually transmitted diseases (especially with a known increased sensitivity to the penicillin group);
  • infection of soft tissue or skin.


The purpose of the drug Vilprafen Solyutab contraindicated in the presence of such conditions and diseases:

  • liver diseases that are severe;
  • sensitivity to josamine or to any of the auxiliary elements;
  • sensitivity reactions to the macrolide group of antibiotics;
  • children whose weight did not reach the figure of 10 kilograms.

Dosing and Administration

For adults and adolescents who have reached the age of 14, the recommended daily dosage is from 1 to 2 grams, divided into 2 to 3 doses. If there is a need to increase the dose, then it is allowed to increase to 3 grams per 24 hours.

In pediatrics in children whose weight has reached 10 kilograms, Vilprafen Soljutab is used at the rate of 40 to 50 mg per kilogram of body weight. This daily dose is divided into 2 or 3 doses.

When the child weighs from 10 to 20 kilograms, a dose of 250 to 500 mg is recommended twice in 24 hours. When taking a quarter or half of the tablet is pre-dissolved in water.

With a body weight of from 20 to 40 kilograms, the dose is from 500 to 1000 mg twice in 24 hours (half or a whole tablet is dissolved in water).

For children weighing more than 40 kilograms, Vilprafen Soljutab is prescribed 1 tablet twice a day.

The course of treatment is prescribed for at least 5 days. In severe conditions, it is allowed to extend it to a 3-week period. In the treatment of tonsillitis caused by streptococcal infection, the course is prescribed for at least 10 days.

Tablets are allowed to be consumed whole, washed down with a liquid, or dissolved in water of at least 20 ml. The suspension should be thoroughly mixed.

Therapy Helicobacter pylori requires a combination of the drug Vilprafen Solyutab with other medications. A dosage of josamine in the amount of 1 gram twice in 24 hours is recommended. The course of treatment from 1 to 2 weeks. In this case, the dose of concomitant drugs remains familiar.

The course of treatment of spherical and common acne is somewhat different. The first 15–30 days of josamine are taken in 500 mg 2 times during the day. A supporting course is then carried out over an 8 week period. At this time, the drug is taken 500 mg 1 time per day.

Side effects

Quite often there are dyspeptic manifestations in the form of a feeling of nausea, the occurrence of emetic urges, diarrhea, discomfort in the epigastrium. Sometimes there are stomatitis, loss of appetite, constipation. Pseudomembranous colitis is extremely rare.

Possible allergic reactions include anaphylactic reactions, edema (including Quincke's edema ), urticaria, erythema, various types of dermatitis.

Rarely, liver dysfunction and jaundice may occur.

There is evidence of hearing impairment, passing independently and directly dependent on the dose of josamine.

Purpura is extremely rare.

special instructions

The threat of pseudomembranous colitis, a disease that seriously endangers the patient’s life, may be indicated by diarrhea that is persistent.

When prescribing josamine to patients with renal insufficiency, laboratory diagnosis and evaluation of blood biochemical parameters are required. Need increased caution in the treatment of these patients.

It is necessary to bear in mind the probability of cross-resistance to macrolide antibiotics.

The drug Vilprafen Soljutab has no effect on the management of complex mechanisms.

Hepatic diseases in severe manifestations are a contraindication to the appointment of funds.

Vilprafen Solyutab is not used in pediatric practice for the treatment of children weighing less than 10 kilograms.

In cases where a patient accidentally forgot to take a dose of Vilprafen Solutab on time, it should be taken as quickly as possible. However, if it is already time for the next dose, you should use the usual dosage.

The success of the therapy depends on the correctly prescribed course and the exact dose of the drug.

Vilprafen Solyutab analogs

Vilprafen Solyutab produced by the manufacturer in various dosage forms. The doctor may prescribe it in the usual (not dissolved previously in the liquid) tablet form, as well as in the form of suspension.

Terms and conditions of storage

Term shelf life 2 years. Storage Vilprafen Solyutab need in a dry place away from a source of sunlight at a temperature of not more than 25 degrees.

Vilprafen Solyutab price tablets 1000 mg

Vilprafen Solutab tablets dispersible 1000mg - 650-700 rubles.

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