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Vicks Active tablets effervescent instructions for use

ATX Ro5X Code

Pharmacotherapeutic group : other drugs used for cough and catarrhal diseases.

Dosage form : mucolytic drug for oral administration.

Form release : round flat effervescent tablets with a risk on one side, white or yellowish, with a lemon smell. Plastic case, cardboard box. 200 mg, 600 mg.

Pharmacological properties

Secret motor, secretolytic.

Composition:

Active ingredient :

  • acetylcysteine.

Auxiliary components :

  • anhydrous citric acid;
  • sodium bicarbonate;
  • fine adipic acid;
  • lemon flavor;
  • aspartame;
  • Povidone.

Pharmacodynamics

Drug for internal use, possessing secretomotor (stimulating expectoration) and secretolytic action. Thins, increases the volume and facilitates the excretion of secreted sputum. Remains active in the presence of mucopurulent mucolytic secretion.

The mechanism of action of effervescent tablets Vicks Active is based on the ability of the sulfide groups of the active component to break the disulfide bonds of acid mucopolysaccharides sputum. As a result, depolarization of mucoproteins occurs and the viscosity of mucus decreases.

Under the influence of acetylcysteine, the synthesis of glutathione increases (an important antioxidant factor of intracellular protection, which maintains the functional activity and morphological integrity of the cell). However, this substance has an antioxidant effect, suppresses the formation of free radicals and active oxygen-containing substances that contribute to the development of inflammation in the lung tissue.

Pharmacokinetics

Effervescent tablets Vicks Active are well absorbed from the digestive tract. Due to the initial passage through the liver, the absolute bioavailability of the drug is reduced by 10%. The maximum concentration in the blood plasma reaches after 1-3 hours. Acetylcysteine ​​is able to penetrate the placenta and accumulate in the amniotic fluid.

In the process of metabolism breaks down to cysteine, cyaceticysteine, cystine and disulfides. It is excreted in the form of inactive metabolites by the kidneys. An insignificant part is allocated together with feces.

In patients with impaired liver function, the maximum concentration of the active ingredient in the blood plasma is observed after 8 hours.


Indications for use

  • Acute and chronic bronchitis ;
  • Pathological conditions, accompanied by the formation of difficult-to-separate viscous mucopurulent sputum;
  • Bronchiolitis;
  • Pneumonia;
  • Bronchial asthma;
  • Tracheitis developed on the background of a viral or bacterial infection;
  • Bronchiectasis;
  • Bronchial occlusion with mucus plug;
  • Cystic fibrosis (as a combination therapy drug);
  • Post-traumatic and postoperative conditions;
  • Purulent and catarrhal otitis media;
  • Various forms of sinusitis (to facilitate the discharge of mucous secretions);
  • Paracetamol overdose.

Contraindications

  • Pregnancy and lactation (in the absence of data on the use);
  • Children's age up to 2 years (for tablets of 200 mg);
  • Age up to 14 years (for tablets of 600 mg);
  • Phenylketonuria;
  • Exacerbation of gastric ulcer and 12 p intestine;
  • Individual intolerance to the components of the drug.

Effervescent tablets Vicks Active are used with extreme caution in bronchial asthma, renal and hepatic pathologies, varicose veins, dysfunction of the adrenal glands, in case of arterial hypertension, the tendency to bleeding and hemoptysis.

Dosage and administration

Tablets are taken after meals, after pre-dissolving in water.

The drug dosage of 600 mg is recommended for adults and children over 14 years. Appointed whole or ½ pill, 2-3 times a day. The maximum daily dose should not exceed 600 mg.

A tablet preparation with a dosage of 200 mg for adults and children after 14 is prescribed 1 tablet 2-3 times a day. Daily dose of 400-600 mg.

Children from 6 to 14 years old - 1 tablet (200 mg), 2 times a day. Daily dose of 400 mg.

Children from 2 to 6 years old - ½ tablet 2-3 times a day (no more than 200-300 mg per day).

In the treatment of cystic fibrosis, children from 2 to 6 years old are prescribed 100 mg of the drug (1/2 tablet) 4 times a day.

Children over 6 years old - 1 tablet (200 mg) 3 times a day.

In chronic cystic fibrosis, long-term use of this drug may be required.


Side effect

As a rule, Vicks Active effektivomed well tolerated by patients. At the same time, in rare cases, the following side effects may develop:

For the skin : allergic reactions, urticaria , angioedema .

Since the cardiovascular system : tachycardia , arterial hypotension.

On the part of the respiratory system : bronchospasm.

On the part of the gastrointestinal tract : nausea, feeling of fullness in the stomach, vomiting, heartburn, impaired stool.

Other disorders: stomatitis, runny nose, tinnitus, nosebleeds, fever, drowsiness.

Drug interactions

The drug is prohibited to use in combination with antitussive drugs that suppress the cough reflex (due to the high risk of sputum in the respiratory tract, leading to the development of serious complications). When prescribing such a combination, it is necessary to constantly monitor the patient’s condition and ensure adequate drainage of sputum.

The active component is capable of inactivating tetracycline antibiotics, ampicillin, aminoglycosides, cephalosporins, and semi-synthetic penicillin antibiotics. Therefore, in the appointment of a combination therapy with the above drugs between the reception should be observed 2-hour interval.

Acetylcysteine ​​is able to potentiate the vasodilating effect of nitroglycerin. When interacting with this drug, there is a decrease in platelet aggregation. Reduces the severity of hepatoxic effects of paracetamol.

Overdose

Data on overdose effervescent tablets Vicks Active effektivomed not. Theoretically, the development of nausea, vomiting, heartburn, pain in the epigastric region, diarrhea.

special instructions

Patients suffering from bronchial asthma, during the period of taking the drug should provide drainage of sputum, as well as parallel use of bronchodilators.

To ensure maximum secretolytic action during treatment, it is required to consume a large amount of fluid.

Tablets should not come into contact with easily oxidizing substances, oxygen, rubber and metal.

Vacation conditions

Refers to non-prescription drugs.

Storage conditions

Store in a dry, protected from light, out of reach of children at a temperature not exceeding 25 C.

Shelf life

The shelf life of the drug is 2 years from the date of issue. After the expiration date indicated on the package, the drug is not allowed to use.

Average price in Moscow pharmacies

200.00 rub.

Vicks Active tablets effervescent analogues

  • ACC Long;
  • ACP 100;
  • ACP 200;
  • Fluimucil.
Rate Weeks Asset effervescent tablets on a 5-point scale:
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