Vikasol tablets instructions for use
- Vikasol tablets instructions for use
ATX Code B02BA02
Pharmacotherapeutic group : haemostatics, blood coagulation factors, coagulants.
Dosage form : tablets for oral administration.
Release form : round tablets of a flat-cylindrical form of white or almost white color, with a facet, cellular planimetric packing, polymeric bottle, cardboard pack.
Synthetic analog of water-soluble vitamin K. Participates in the formation of prothrombin. Contributes to the normalization of blood clotting.
Active ingredient :
- Sodium Menadione Bisulfite
Auxiliary components :
- potato starch;
- calcium stearate.
The preparation of the vitamin K group, which has a hemostatic effect. Due to the increased production of hemocoagulation factors X, 1X, V11, 11 in the liver, it contributes to an increase in blood clotting. Participates in the synthesis of prothrombin and proconvertin. Substrate stimulates the enzyme K-vitamin reductase. This biologically active component activates vitamin K and ensures its participation in the hepatic synthesis of plasma hemostasis factors.
Vikasol has hemostatic properties, which manifest a maximum after 18 hours after taking the drug.
The drug is rapidly absorbed, the relationship with plasma proteins is reversible. In small quantities, it can accumulate in the liver, myocardium and spleen. Once in the body, it is transformed into vitamin K. This process is most intense in skeletal muscle and myocardium. Slightly weaker - in the renal tissue. After going through a cycle of metabolic activation, it is oxidized in the liver to the diol form. Excreted in the form of metabolites by the kidneys and intestines, along with bile. Due to the synthesis of vitamin K intestinal microflora there are high concentrations of this biologically active component in feces.
Indications for use
- Obstructive jaundice, which is a consequence of the late entry into the intestine of bile;
- Parenchymal and capillary hemorrhages accompanying peptic ulcer and 12p intestine;
- Long nasal and hemorrhoidal bleeding;
- Thrombocytopenic purpura;
- Radiation sickness;
- Pulmonary hemorrhage;
- Juvenile and dysfunctional uterine bleeding;
- Bleeding caused by injuries;
- Bleeding with tuberculosis;
- Bleeding caused by septic conditions;
- Overdose of indirect anticoagulants;
- Hemorrhagic events in premature babies;
- Individual intolerance to the components of the drug;
- Hemolytic disease of the newborn.
Dosage and administration
The average daily dose for adults is 15-30 mg, for children up to 12 months - 2-5 mg, up to two years - 6 mg, 3-4 years - 8 mg, 5-9 years - 10 mg, 10-14 years - 15 mg. Tablets are recommended to take no more than 3 times a day. The course of treatment, the daily and one-time dosage of the drug is prescribed by the attending physician on an individual basis.
- Hypervitaminosis (elevated vitamin K);
- Increased prothrombin, thrombin and bilirubin;
- Toxicosis (in childhood);
- Allergic skin reactions (itching, erythema, urticaria );
- Cramps .
When using Vikasol with vitamin K antagonists (phenylin, neodicoumarin, etc.), their anticoagulant properties are blocked. When taken simultaneously with antibacterial drugs, salicylates, sulfonamides and quinidine dose adjustment Vikasola is required.
Medical science does not have data on overdose of the drug.
Refers to non-prescription drugs.
Store in a dry, protected from light, out of reach of children at a temperature not exceeding 25 C.
The shelf life of the drug for 3 years from the date of issue. After the expiration date indicated on the package, the drug is not allowed to use.
Tablets Vikasol price
The average price in Moscow pharmacies is 54.00 rubles.
Analogs of Vikasol Tablets
- Menadione sodium bisulfite;