The Vikasol: instructions for use, indications for menstrual bleeding, price, reviews, analogues of tablets Vikasol
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Vikasol tablets user manual

ATX code B02BA02

Pharmacotherapeutic group : hemostatics, coagulation factors, coagulants.

Dosage form : tablets for oral administration.

Product : round tablets of flat-cylindrical shape of white or almost white color, with a facet, a cellular contour wrap, a polymeric bottle, a cardboard bundle.

Pharmacological properties

Synthetic analogue of water-soluble vitamin K. It participates in the formation of prothrombin. Helps normalize blood coagulability.



Composition:

Active substance :

  • Bisulfite maleadione sodium

Auxiliary components :

  • potato starch;
  • lactose;
  • Calcium stearate.

Pharmacodynamics

The drug is a group of vitamin K, which has a hemostatic effect. Due to the increased production in the liver of hemocoagulation factors X, 1X, V11, 11, promotes an increase in blood coagulability. Participates in the synthesis of prothrombin and proconvertin. Substrate stimulates the enzyme K-vitamin reductase. This biologically active component activates vitamin K and ensures its participation in hepatic synthesis of plasma factors of hemostasis.

Vikasol has hemostatic properties, manifested at most 18 hours after prima remedy.

Pharmacokinetics

The drug is rapidly absorbed, the connection with plasma proteins is reversible. In small amounts it is able to accumulate in the liver, myocardium and spleen. Getting into the body, it is transformed into vitamin K. The most intense this process occurs in skeletal muscles and myocardium. Slightly weaker - in the kidney tissue. After passing a cycle of metabolic activation, it is oxidized in the liver to a diol form. It is excreted as metabolites by the kidneys and intestines, together with bile. Due to the synthesis of vitamin K by the intestinal microflora, high concentrations of this biologically active component in feces are observed.


Indications for use

  • Obturation jaundice, which is the result of ill-timed entry into the intestines of bile;
  • Hepatitis;
  • Parenchymal and capillary bleeding, accompanying peptic ulcer and 12p intestine;
  • Prolonged nasal and hemorrhoidal hemorrhages;
  • Thrombocytopenic purpura;
  • Radiation sickness;
  • Pulmonary haemorrhage;
  • Juvenile and dysfunctional uterine bleeding;
  • Hemorrhages, provoked by wounds;
  • Bleeding at tuberculosis;
  • Bleeding, provoked by septic states;
  • Overdose of indirect anticoagulants;
  • Hemorrhagic phenomena in premature infants;
  • Surgical operations.

Contraindications

  • Individual intolerance to the components of the drug;
  • Thromboembolism;
  • Hypercoagulation;
  • Hemolytic disease of newborns.

Dosing and Administration

The average daily dose of the drug for adult patients is 15-30 mg, children up to 12 months - 2-5 mg, up to two years - 6 mg, 3-4 years - 8 mg, 5-9 years - 10 mg, 10-14 years - 15 mg. Tablets should not be taken more than 3 times a day. The course of treatment, daily and one-time dosage of the drug is prescribed by the attending physician on an individual basis.

Side effect

  • Hypervitaminosis (increased content of vitamin K);
  • Increased prothrombin, thrombin and bilirubin;
  • Toxicosis (in childhood);
  • Bronchospasm;
  • Skin allergic reactions (itching, erythema, urticaria );
  • Convulsions .

Drug Interactions

With the simultaneous use of Vikasol with antagonists of vitamin K (phenylene, neodicumarin, etc.), their anticoagulant properties are blocked. With simultaneous administration with antibacterial drugs, salicylates, sulfonamides and quinidine, dose adjustment of Vikasol is required.

Overdose

Medical science does not have data on drug overdose.

Leave conditions

Refers to non-prescription drugs.

Storage conditions

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 25 ° C.

Shelf life

Shelf life of the drug is 3 years from the date of issue. After the expiry date indicated on the package, the drug should not be used.

Tablets Vikasol price

The average price in pharmacies in Moscow is 54.00 rubles.

Analogues of tablets Vikasol

  • Menadione sodium bisulfite;
  • Agamphil;
  • Benefit;
  • Batroksobin;
  • Hemomectin;
  • Dicycin;
  • Immunate;
  • Immunin;
  • Collagen;
  • Caprofer;
  • Thrombin;
  • Pheracril.
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