The Vikasol ampoules: instruction manual, price, reviews, analogues of injections Vikasol
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Vikasol solution in ampoules: instructions for use

This drug is designed to quickly normalize the process of blood coagulability. Vicasol is considered to be an analogue of vitamin K, obtained by an artificial method. Participates in the process of prothrombin formation. If the body lacks vitamin K, then hemorrhagic manifestations occur.

Form of issue and composition

Cardboard package Vikasola contains 10 pieces of ampoules with a volume of 1 ml. The content of the active component - vicasol - in 1ml 10 mg. The excipients are water for injection, sodium metabisulphite and hydrochloric acid. Each ampoule contains information about the production series and the term of validity. This data is also on the secondary packaging. In addition to the ampoules inside the container is a detailed instruction.

Indications for use

Vicasol is usually prescribed by the attending physician under such conditions:

  • jaundice, which appeared due to the delay in the process of entering the bile in the liver;
  • hepatitis in acute manifestations;
  • a variety of bleeding from both internal organs and capillary (before and after surgical manipulation);
  • ulcers of the digestive tract, accompanied by bleeding of different severity;
  • hemorrhages for the mucous membranes and skin that occur when the platelet count is lowered in the blood test (purpura thrombocytopenic);
  • bleeding from the nose and rectum of a persistent nature (with hemorrhoids);
  • pregnancy in the third trimester (to prevent bleeding in a newborn) - the appointment is done individually by a doctor;
  • radiation sickness;
  • bleeding hemorrhagic in newborns;
  • prolonged uterine juvenile and pre-menopausal hemorrhages;
  • tuberculosis of the lungs, accompanied by bleeding;
  • various septic diseases with bleeding;
  • hypoprothrombinemia;
  • use of anticoagulants, which are considered antagonists of vitamin K.

Vikasol is ineffective in the treatment of Verlhof's disease and hemophilia.

Contraindications

The drug should not be administered with high blood coagulability, with thromboembolism, hemolytic disease in newborns, as well as in reactions of individual sensitivity to both the main component and any auxiliary substance.

Caution is needed in pregnancy, deficiency of glucose-6-phosphate dehydrogenase and liver failure.

Dosing and Administration

Vicasol is used only by intramuscular injection. The dose for an adult should be 10 to 15 mg of vikasol once. The daily dose for this age group is 30 mg.

The use in children varies significantly depending on age. Dosage in newborns and children up to 12 months is 0.4 mg per kilogram of body weight per day. From year to 2 years, the daily dose of 6 mg. From 3 to 4 years - 8 mg for 24 hours. From the age of 5 years and up to the 9-year period, a daily dose of 10 mg. From 10 to 14 years, the dosage of Vikasol is 15 mg per day. The drug is prescribed 2 to 3 times in 24 hours. The course of therapy is usually 3 to 4 days. Repeat the course is allowed after a 4-day break. The choice of the duration of treatment is determined by the doctor.

The prothrombin index is determined 3 hours after the administration of the drug Vikasol. If this indicator does not correspond to the norm, then the administration is performed again, but taking into account the fact that the daily dose can not exceed 40 mg of vikasol.

If it is necessary to carry out serious surgical procedures with the probability of severe parenchymal hemorrhage, the drug is prescribed 2 or 3 days before the operation.

Patients of the older age group are more sensitive to Vikasol. When choosing the dosage for them, you should focus on the lower limits of the recommended values.


Side effects

Drug medication can cause such undesirable side symptoms:

  • the appearance of tenderness and swelling at the site of the injection. With repeated administration, sometimes spots appear on the skin;
  • bronchospasm;
  • rash on the skin. It can be accompanied by erythema, itching and hives;
  • hemolysis in neonates with congenital deficiency of glucose-6-phosphate dehydrogenase;
  • hemolytic anemia;
  • hyperbilirubinemia;
  • the appearance of dizziness;
  • jaundice;
  • decrease in blood pressure indicators;
  • a change in the sense of taste;
  • sudden sweating;
  • occurrence of tachycardia.

Symptoms that can develop with a random overdose: hyperbilirubinemia, toxicosis with convulsions (a symptom more characteristic of children), hyperprothrombinemia. With these manifestations of an overdose, anticoagulants and stopping the application of Vikasol are prescribed.

special instructions

The drug is absolutely ineffective in the treatment of Verlhof disease or hemophilia. During the third trimester of pregnancy, the prophylactic use of Vikasol is impractical because of the low permeability of the placenta for it. It is recommended to prevent hemorrhagic disease in newborn children not with Vikasol, but with phytomenadione, which provokes less frequent development of side symptoms.

If the bleeding is extensive and severe, then only Vikasol therapy will be inadequate. Transfusion of blood elements is necessary. The earliest effect after administration of the drug always develops only 8 hours after the injection.

If long-term treatment with Vikasol is to be carried out, then control over the coagulation factors is regularly carried out.

Vikasol in no way affects the anticoagulant ability of heparin. Significantly weakens the effectiveness of indirect anticoagulants. An increase in the dosage of vitamin K is required when antibiotics, quinine, salicylates in high doses, quinidine and sulfonamides are used antibacterially.

Use with drugs that can provoke a hemolytic crisis in patients suffering from a deficiency of glucose-6-phosphate dehydrogenase increases the likelihood of the development of adverse events.

The need for application of Vikasol in the therapy with Warfarin is assessed additionally.

Analogues

To the analogues of Vikasol include Menadion and vitamin K.


Terms and conditions of storage

Ampoules should be stored only in dark places far from children at temperature values ​​not exceeding 25 degrees.

Vikasol ampoules price

Vikasol injection 1% - 60-80 rub.

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