The Vibrocil Spray: instructions for use, indications for children, price, reviews
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Vibrocil Spray: instruction manual

ATX code R01AB01

Pharmacotherapeutic group : anticongestant (decongestant for removing the edema from the mucous membrane).

Dosage form : nasal spray.

Form release : solution, clear, or light yellow color, with a faint smell of lavender.

Pharmacological properties

Antiallergic, vasoconstrictive, anticonvulsant.



Composition:

Active substance :

  • Phenylephrine;
  • Male dimethindene.

Auxiliary components :

  • Monohydrate of citric acid;
  • sorbitol;
  • Anhydrous sodium hydrophosphate;
  • Hypromellose;
  • Lavender oil;
  • 50% benzalkonium chloride solution;
  • purified water.

Pharmacodynamics

Combined drug containing in its composition 2 active components.

Phenylephrine is a symptomatic remedy, with topical application, by stimulating α1-adrenoreceptors of the venous vessels of the nasal mucosa, has a vasoconstrictive effect, eliminates edema of the nasal mucosa and airway sinuses.

Dimethinden is an antiallergic component, an antagonist of H1-histamine receptors, which does not reduce the activity of the ciliated epithelium of the nasal mucosa.

Pharmacokinetics

Vibrocil Spray is a topical drug. As a consequence, its activity does not correlate with the concentration of active substances in the blood plasma.

In case of accidental ingestion of the agent on the oral mucosa and subsequent absorption of phenylephrine, the bioavailability reaches approximately 38%, the elimination half-life is 2.5 hours.


Indications for use

The drug is used as a symptomatic agent in the following conditions:

  • colds;
  • nasal congestion;
  • Acute and chronic rhinitis;
  • Allergic rhinitis;
  • Acute otitis media (as an adjuvant therapy);
  • Preoperative preparation and postoperative elimination of edema of the nasal mucosa and accessory sinuses.

Contraindications

  • Hypersensitivity and individual intolerance of the components of the drug;
  • Atrophic rhinitis;
  • When taking monoamine oxidase inhibitors;
  • Children under 6 years;
  • Pregnancy and lactation.

Dosing and Administration

Before irrigation of the nasal cavity, it is recommended to thoroughly clean the nasal passages. Adults and children who reached the age of 6, it is recommended to use the drug 3-4 times a day, 1-2 injections. The bottle should be kept strictly vertical when injecting the nebulizer into the nasal cavity. After injecting the spray, you need to inhale slightly through the nose. The course of treatment should not exceed 7 days.

Side effect

In rare cases, the development of local allergic reactions (burning or drying of the mucous membrane of the nasal cavity) is possible.

Drug Interactions

Vibrocil Spray is not recommended for use in combination with monoamine oxidase inhibitors (including if the drug was taken in the previous 14 days).

The vasoconstrictor with special caution is prescribed for patients taking antihypertensive drugs and tricyclic antidepressants.

special instructions

Vibrocil Spray is not recommended for use by children under 6 years of age. Long-term (more than a week) application can lead to the development of tachyphylaxis and provoke the development of drug rhinitis (the so-called ricochet effect). If the recommended dose of the drug is exceeded, its systemic effect may be manifested. Does not have a sedative effect and does not affect the speed of psychomotor reactions.

Leave conditions

Refers to non-prescription drugs.

Storage conditions

Store in a dry place, protected from light, out of reach of children, at a temperature not exceeding 30 ° C.

Shelf life

Shelf life of the drug is 3 years from the date of issue. After the expiry date indicated on the package, the drug should not be used.

Average price in pharmacies in Moscow

220.00 rub.

Vibrocyl Spray Analogs

  • Alergomax;
  • Grippotsitron rinis;
  • Edenino.
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