Vibrocil Gel: instructions for use
- Vibrocil Gel: instructions for use
- Form of preparation, its composition and packaging
- Mechanism of action
- When is it applied?
- When and to whom it is not recommended to apply
- Mode of application
- Symptoms of an overdose of Vibrocil Gel and their treatment.
- Interaction of Vibrocil Gel with other drugs
- Application of Vibrocil gel during pregnancy and lactation
- Side effects
- How and where to store?
- Conditions of leave from pharmacies
- Vibrocil Gel price
Vibrocil gel is a combined drug, with antiallergic and vasoconstrictive action. Used externally, intranasally.
Form of preparation, its composition and packaging
Vibrocil gel is available as a uniform colorless or pale yellow gel. Has a weak lavender aroma. Does not contain mechanical impurities and impurities.
Available in aluminum tubes with a special tip of 12 g. Tubes of 1 piece are enclosed in cardboard packs.
1 gram of gel Vibrocil contains 2.5 mg of phenylephrine and 250 μg of dimethindene maleate. Also as additional substances: anhydrous sodium hydrogenphosphate, sorbitol, citric acid, lavender oil, purified water, hypromelose, benzalkonium chloride solution 50%.
Mechanism of action
Vibrocil Gel is a combined preparation containing vasoconstrictor-phenylephrine and antiallergic - dimethindene.
Phenylephrine is a stimulator of α1-adrenergic receptors located in the nasal mucosa. Due to this, there is a narrowing of the vessels and removal of swelling from the mucous membranes and adnexal sinuses.
Dimetinden acts by blocking H1-histamine-dependent receptors. Prevents the development of the allergic process, does not inhibit the work of the ciliated epithelium.
Vibrocil gel is a topical agent and its effectiveness does not depend on the penetration of active substances into the systemic bloodstream.
The dosage form of the gel makes it possible to provide the drug with a longer activity in comparison with drops and spray.
When is it applied?
Vibrocil gel is used to treat rhinitis of various origins, namely:
- acute or chronic
And also with acute otitis media (as part of complex treatment) and before surgical intervention on the areas of the nose and nearby tissues.
When and to whom it is not recommended to apply
Do not apply Vibrocil Gel in rhinitis with atrophy of the nasal mucosa, against the backdrop of the use of MAO inhibitors, children under 6 years of age and with individual sensitivity to the ingredients of the drug.
Care should be taken in the use of patients with diseases of the cardiovascular system, the thyroid gland. Perhaps worsening of patients with glaucoma is closed with a coal type, BPH, type 1 diabetes mellitus.
Carefully monitor the condition of patients with increased reactivity to sympathomimetics (insomnia, dizziness).
Mode of application
Before applying Vibrocil Gel, the nasal passages from the mucous secretions characteristic of rhinitis should be thoroughly cleaned.
Using a special tip on the tube, the gel is injected as deep as possible into the nasal passages 3-4 times throughout the day. It is used for children from 6 years old and for adults. When applying a layer of gel before bedtime, the effectiveness of the drug persists throughout the night period, that is, normal nasal breathing is restored, there is no obstruction and discharge.
Symptoms of an overdose of Vibrocil Gel and their treatment.
There are no data on serious symptoms of an overdose with Vibrocil. In case of accidental use of the medicine, no side effects were seen inside the children.
Sometimes patients complained about:
- pains in the stomach
- sleep disturbance
- raising the level of hell
- cardiac rhythm disturbance
- pallor of the skin (in children)
In case of an overdose of Vibrocil Gel, you should take activated charcoal or another sorbent, and also consume large amounts of liquid. Specifically, there is no antidote to Vibrocil.
Interaction of Vibrocil Gel with other drugs
Do not use Vibrocil Gel on the background of taking monoamine oxidase inhibitor preparations, because of the content of the vasoconstrictor component of phenylephrine. Between the last reception of MAO inhibitors and the use of Vibrocil Gel should be at least 14 days.
It is not recommended joint use of Vibrocil gel with antidepressants and drugs for the treatment of hypertension.
Application of Vibrocil gel during pregnancy and lactation
Since there is a possibility of developing a systemic vasoconstrictive effect of phenylephrine, which is part of the Vibrocil Gel, do not use this drug during pregnancy and breastfeeding.
Vibrocil gel is a topical agent and does not have systemic side effects.
As a local reaction, there may be mild burning and dryness of the mucous membrane.
How and where to store?
Vibrocil gel is stored at a temperature of up to 30 ° C. Do not use the drug for more than 3 years from release. Keep away from children.
Conditions of leave from pharmacies
Vibrocil gel belongs to the list of non-prescription drugs.
Vibrocil Gel price
Vibrocil Gel 12g - 220-280 rub.