Vermoxes instructions for use
Vermox tablets belong to the pharmacological group of drugs - antihelminthic drugs. The main active ingredient of the drug mebendazole leads to the death of various types of helminths, therefore these tablets are used for etiotropic therapy of the corresponding helminth infections in children and adults. The drug is most effective against pathogens trichocephalosis and enterobiosis.
Release form and composition
Vermox tablets are round and white in color. The main active ingredient is contained in an amount of 100 mg, also contains auxiliary components, which include:
- Colloidal silicon dioxide - 1.5 mg.
- Sodium lauryl sulfate - 0.5 mg.
- Magnesium stearate - 3 mg.
- Talc - 9 mg.
- Sodium Saccharinate - 5 mg.
- Corn starch - 71 mg.
- Lactose monohydrate - 110 mg.
Vermox tablets are packaged in a blister of 3 pieces. The carton pack contains 2 blisters and instructions for use of the drug.
Many people are interested in the question: how Vermox acts on the worms, how does it then go out of their body. The main active ingredient of Vermox tablets is mebendazole. This substance selectively blocks the synthesis of cellular protein tubulin helminths, which leads to disruption of the processes of absorption and adsorption of nutrients (in particular glucose) and the development of energy starvation, followed by death of the parasite and its excretion through the intestines. Mebendazole also inhibits the synthesis of ATP molecules (adenosine triphosphoric acid - the main accumulator of cell energy) of helminth cells, which aggravates their energy starvation. The active ingredient of Vermox tablets has a wide spectrum of action against the majority of helminths, pathogens of parasitosis (helminthiasis). The drug is most actively destroying the helminths pathogens of trichocephalosis and ascariasis.
After taking Vermox tablets orally, mebendazole is absorbed into the blood in a small amount, where it immediately binds to plasma proteins and is metabolized in the liver to intermediate degradation products. Most of the active substance is excreted from the intestine with feces, about 10% - by the kidneys in urine.
Indications for use
Vermox tablets are indicated for the treatment of parasitic diseases caused by various types of worms, these include:
- Ascariasis - parasitism in the intestines of ascaris (representatives of the class of roundworms).
- Trichocephalosis - intestinal worms class of roundworms.
- Enterobiasis - helminthiasis caused by pinworms (belong to the class of roundworms), which parasitize in the lower intestine, mainly in children.
- Ankilostomidoz - an intestinal parasite with a predominant localization in the duodenum, belongs to the roundworms, often leads to the development of anemia (anemia).
- Trichinosis is a helminth class of nematodes, characterized by parasitizing larvae in muscles and internal organs.
- Tenioz and cysticercosis - parasitization in the intestines of the pork tapeworm, which can be in the form of an adult or the larval stage.
- Alveococcosis - helminthiasis caused by flatworm larvae that parasitize the liver.
- Echinococcosis - has a certain similarity with alveococcosis, mainly affects the liver and lungs.
- Capillaria - pathology caused by the smallest helminths capillaries.
- Gnatostomosis is a parasitism of small nematode-class helminths that leads to the formation of characteristic nodules in the skin.
Also, the use of Vermox tablets is indicated for mixed helminthiasis caused by several parasites at once.
Vermox tablets are contraindicated in a number of pathological and physiological conditions of the body, which include:
- Individual intolerance or hypersensitivity to mebendazole or other auxiliary components of the drug.
- Crohn's disease is a chronic non-specific inflammatory process in the colon.
- Ulcerative colitis is a chronic inflammation of the mucous membrane of the colon with the formation of ulcers and erosions.
- The presence of liver failure.
- Pregnancy at any time and breastfeeding.
- Children's age up to 2 years.
Before you start using Vermox tablets, you must make sure that there are no contraindications.
Dosing and Administration
Vermox tablets are taken internally, without chewing, washed down with a small amount of water. The dosage depends on the age and type of helminth, which led to the development of pathology:
- Adults and children over 2 years old with enterobiasis - 100 mg (1 tablet) 1 time a day, with mixed helminthiasis - 100 mg 2 times a day, for 3 days. If the symptoms of helminthiasis persist, the treatment is repeated after 3 weeks.
- Children older than 14 years and adults - with mixed helminthiasis and enterobiasis, the dosage regimen is the same. With echinococcosis, the dose is significantly higher - 500 mg (5 tablets) 2 times a day for the first 3 days, then the dose is increased to an additional 500 mg 3 times a day for another 3 days. In the future, if necessary, the dose can be increased to 1000-1500 mg 3 times a day. The average course of treatment is 4-6 weeks (for parasitic echinococcus Echinococcus multilocularis, the course is long, up to 2 years).
For the treatment of trichinosis, the drug is taken according to this scheme - 1st day 200-300 mg 3 times a day, 2nd day 200-300 mg 4 times a day, and from 3rd day to 14th day 500 mg 3 times a day. For ascariasis, teniasis, hookworm, trichuriasis, strongyloidosis, the recommended regimen is 100 mg 2 times a day (morning and evening) for 3 days.
Also in parallel, it is recommended to take a prophylactic administration of the drug to family members or close people who also have the chance of getting helminthiasis.
After taking Vermox tablets, side effects may develop in the form of headache, nausea, vomiting, and abdominal pain. Also, rarely develop allergic reactions in the form of a skin rash, itching or urticaria (a characteristic skin rash and swelling, resembling a nettle burn). When using high dosages, abnormalities may develop in the liver, indicating hepatocyte damage (an increase in the level of liver transaminase enzymes in the blood). A long course of drug treatment is the cause of leukopenia (a decrease in the number of leukocytes in the blood). In the case of side effects, the drug should be stopped and seek medical help.
Before taking Vermox tablets, you should carefully read the instructions. There are several specific indications regarding the use of the drug, which include:
- When using Vermox tablets in patients with insulin-dependent diabetes mellitus, the need for insulin is reduced, it must be taken into account to prevent the development of hypoglycemia (a significant decrease in blood sugar levels).
- After completing the course of treatment, it is necessary to carry out laboratory monitoring of its effectiveness (analysis of feces on helminth eggs or other studies).
- With a long course of Vermox tablets, periodic laboratory monitoring of the functional state of the liver, kidneys and red bone marrow is carried out.
- While taking the drug in any dosage, the use of alcohol is excluded.
- It is not recommended to combine Vermox tablets with drugs that have the ability to accumulate in adipose tissue.
- Special dietary recommendations or the use of laxative medicines while taking Vermox tablets do not need to be performed.
- The drug does not affect the concentration and speed of psychomotor reactions.
In the pharmacy network, Vermox tablets are sold without a prescription. However, it is recommended to use the drug only as prescribed by a physician, in order to avoid overdose or the development of side effects.
With a significant excess of the recommended therapeutic dose may develop headache, nausea, vomiting, diarrhea, abdominal pain. In this case, the drug is stopped, the gastric and intestinal lavages are performed and symptomatic therapy is given.
Analogues for therapeutic action for Vermox tablets are Albenzene, Mebendazole, Wormil.
Terms and conditions of storage
The shelf life of the drug from the time of manufacture is 5 years. Vermox tablets should be stored in a dark, dry, out of the reach of children place at a temperature range from +15 to + 30 ° C.
The average cost of Vermox tablets in pharmacies in Moscow is 89-91 rubles.