Valaciclovir instructions for use
- Valaciclovir instructions for use
- Form of formulation and composition of the preparation
- Pharmacological properties of the drug
- Indications for use
- Contraindications for use
- Method of administration and dosage
- Side effects
- Use of the drug during pregnancy and lactation
- special instructions
- Storage and dispensing conditions
- Valaciclovir price
Valaciclovir is a drug for use within the antiviral effect. The drug is especially effective against herpesviruses 1 and 2 types, cytomegalovirus, Epstein-Barr virus and others, with the exception of HIV.
Form of formulation and composition of the preparation
The drug valaciclovir is available in the form of tablets for ingestion of white color, covered with a protective film shell. Tablets are packed in a cardboard package in a blister for 10 pieces. Each tablet contains 500 mg of active active substance valacyclovir, as well as auxiliary components.
Pharmacological properties of the drug
Tablets are for oral use. After taking the drug inside active substance under the influence of certain chemical processes is completely converted into acyclovir. Acyclovir easily penetrates into the cells and tissues infected by viruses and has a harmful effect on them. The activity of the active ingredient can be called highly selective, since the drug penetrates only into the affected structures without affecting healthy tissues and cells. Acyclovir exerts a high therapeutic effect on herpes simplex virus type 1 and 2, cytomegalovirus , Epstein-Barr virus.
Indications for use
This drug is prescribed to patients for the purpose of treatment or prevention of such conditions:
- Herpetic eruptions on the skin and mucous membranes of the lips;
- Genital herpes;
Contraindications for use
This drug is not used in patients with an individual intolerance to the main active ingredient or the auxiliary components of the tablet. The drug is also not prescribed for the treatment of children less than 12 years of age.
Method of administration and dosage
Depending on the diagnosis, the age of the patient and the individual characteristics of the body, the daily dosage of the drug is determined by the doctor.
According to the instructions to the drug, Valaciclovir tablets are prescribed to patients for treatment of shingles at a rate of 1-2 tablets 3 times a day. The duration of the course of therapy is at least 1 week.
For the treatment of herpetic infection of the skin or genital herpes, the drug is prescribed 1 tablet 2 times a day. In order to prevent the development of recurrence of herpes or in direct contact with the patient should take 1 tablet of Valaciclovir 1 time per day for 1 week. If necessary, the preventive course of treatment lasts up to 10 days.
Patients with severe violations of the liver and kidney function daily dose of the drug is slightly corrected. Such patients on the background of drug therapy constantly monitor the clinical picture of blood and general condition.
In most cases, the drug Valocyclovir is well tolerated by patients, but with individual hypersensitivity, the following side effects may develop:
- On the part of the organs of the digestive canal - pain in the stomach, nausea, vomiting, decreased appetite, diarrhea;
- From the side of the nervous system - dizziness and headaches, fatigue and general weakness, sleep disturbances and psychoemotional excitability;
- On the part of the clinical picture of blood - a decrease in the number of platelets, hemolytic anemia, an increase in hepatic transmnaz;
- Development of renal failure.
When an overdose of the drug in patients observed deposition of the active substance in the tubules of the kidneys, as a result of which they begin to work inadequately. Treatment of an overdose consists in carrying out hemodialysis - provided the development of anuria and renal failure.
Use of the drug during pregnancy and lactation
Valaciclovir tablets are not prescribed for the treatment of pregnant women in the first trimester, due to the lack of reliable data on the safety of the drug for the fetus. In addition, in the first 12 weeks of pregnancy, gynecologists do not recommend that women take any medications, as during this period, all organs and systems are laid, and the impact of medications can roughly break this delicate process.
The use of Valaciclovir tablets in the 2nd and 3rd trimesters of pregnancy is possible if the expected benefit to the mother is higher than the possible risk to the fetus. The drug is administered strictly under the supervision of the doctor in the lowest effective dosage.
The active substance of the drug easily penetrates into breast milk, and then into the body of the child with food. Although there are no facts about the toxicity of acyclovir on the baby, it is not recommended to prescribe this drug during lactation. If it is necessary to use tablets during breastfeeding, a woman should decide on the transfer of the child to an adapted milk formula.
If you need to use this medication in the elderly, you should ensure that the amount of fluid consumed per day is slightly higher than normal. This is necessary in order to prevent the deposition of the drug components in the tubule of the kidneys.
In the treatment of this drug of genital herpes, patients during this period should be excluded from sexual intercourse in order to prevent transmission of infection to the partner. It is also advisable for a sexual partner to undergo a course of treatment with the drug, otherwise the infection will be transmitted to each other in the future.
Storage and dispensing conditions
Valaciclovir tablets are dispensed in pharmacies without a doctor's prescription. Keep the drug in a safe, inaccessible place for children, at a temperature of not more than 25 degrees. Shelf life of the drug is 3 years from the date of manufacture, indicated on the package. After this period, tablets should not be taken orally.
The cost of tablets Valaciclovir in pharmacies in Moscow is an average of 500-580 rubles per package.