Valaciclovir instructions for use
- Valaciclovir instructions for use
- Form of formulation and composition of the preparation
- Pharmacological properties of the preparation
- Indications for use
- Contraindications for use
- Method of administration and dosage
- Side effects
- Use of the drug during pregnancy and lactation
- special instructions
- Storage and dispensing conditions
- Valaciclovir price
Valaciclovir is a drug for use within the antiviral effect. The drug is particularly effective against herpesviruses 1 and 2 types, cytomegalovirus, Epstein-Barr virus and others, with the exception of HIV.
Form of formulation and composition of the preparation
The drug valaciclovir is available in the form of tablets for ingestion of white color, covered with a protective film shell. Tablets are packed in a cardboard package in a blister for 10 pieces. Each tablet contains 500 mg of active active substance valacyclovir, as well as auxiliary components.
Pharmacological properties of the preparation
Tablets are for oral use. After taking the drug inside the active substance under the influence of certain chemical processes is completely converted into acyclovir. Acyclovir easily penetrates into cells infected by viruses and tissues and has a disastrous effect on them. The activity of the active ingredient can be called highly selective, since the drug penetrates only into the affected structures without affecting healthy tissues and cells. Acyclovir has a high therapeutic effect on herpes simplex virus type 1 and 2, cytomegalovirus , Epstein-Barr virus.
Indications for use
This drug is prescribed to patients for the purpose of treatment or prevention of such conditions:
- Herpetic eruptions on the skin and mucous membranes of the lips;
- Genital herpes;
Contraindications for use
This drug is not used in patients with an individual intolerance to the main active ingredient or the auxiliary components of the tablet. The drug is also not prescribed for the treatment of children less than 12 years of age.
Method of administration and dosage
Depending on the diagnosis, age of the patient and individual characteristics of the body, the daily dosage of the drug is determined by the doctor.
According to the instructions to the drug, Valaciclovir tablets are prescribed to patients for treatment of shingles at a rate of 1-2 tablets 3 times a day. The duration of the course of therapy is at least 1 week.
For the treatment of herpetic infection of the skin or genital herpes, the drug is prescribed 1 tablet 2 times a day. In order to prevent the development of recurrence of herpes or with direct contact with the patient should take 1 tablet of Valaciclovir 1 time per day for 1 week. If necessary, the preventive course of treatment lasts up to 10 days.
Patients with severe violations of the liver and kidney function daily dose of the drug is corrected somewhat. Such patients on the background of drug therapy constantly monitor the clinical picture of blood and general condition.
In most cases the preparation Valocyclovir is well tolerated by patients, however, with individual hypersensitivity, the following side effects may develop:
- On the part of the organs of the digestive canal - pain in the stomach, nausea, vomiting, decreased appetite, diarrhea;
- From the side of the nervous system - dizziness and headaches, fatigue and general weakness, sleep disturbances and psychoemotional excitability;
- On the part of the clinical picture of blood - a decrease in the number of platelets, hemolytic anemia, an increase in liver transaminases;
- Development of renal failure.
When an overdose of the drug in patients observed deposition of the active substance in the tubules of the kidneys, as a result of which they begin to work inadequately. Treatment of an overdose consists in the conduct of hemodialysis - provided the development of anuria and renal failure.
Use of the drug during pregnancy and lactation
Valaciclovir tablets are not prescribed for the treatment of pregnant women in the first trimester, due to the lack of reliable data on the safety of the drug for the fetus. In addition, in the first 12 weeks of pregnancy, gynecologists do not recommend that women take any medications, as during this period, all organs and systems are laid, and the effects of medications can roughly break this delicate process.
The use of valacyclovir tablets in the 2nd and 3rd trimester of pregnancy is possible if the expected benefit for the mother is higher than the possible risk to the fetus. The drug is administered strictly under the supervision of the doctor in the lowest effective dosage.
The active substance of the drug easily penetrates into breast milk, and then into the body of the child with food. Although there are no facts about the toxicity of acyclovir on the infant, it is not recommended to prescribe this drug during lactation. If it is necessary to use tablets during breastfeeding, a woman should decide whether to transfer the baby to an adapted formula.
If you need to use this medication in the elderly, you should ensure that the amount of fluid consumed per day is slightly higher than normal. This is necessary in order to prevent the deposition of the drug components in the tubule of the kidneys.
When treating this drug with genital herpes, patients should be excluded from sexual intercourse during this period in order to prevent transmission of infection to the partner. It is also advisable for a sexual partner to undergo a course of treatment with the drug, otherwise the infection will be transmitted to each other in the future.
Storage and dispensing conditions
Valaciclovir tablets are dispensed in pharmacies without a doctor's prescription. Keep the drug in a safe, inaccessible place for children, at a temperature of not more than 25 degrees. Shelf life of the drug is 3 years from the date of manufacture, indicated on the package. At the end of this period, tablets should not be taken orally.
The cost of tablets Valaciclovir in pharmacies in Moscow is an average of 500-580 rubles per package.