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Budesonide for inhalation instructions for use

Budesonide is an inhaled glucocorticosteroid that has a local anti-inflammatory, antiexudative and anti-allergic effect. It is used for Crohn's disease, bronchial asthma and chronic obstructive pulmonary disease.

International drug name: Budesonide (Budesonide)

Pharmacotherapeutic group: Inhalation glucocorticosteroid

Active ingredient: Budesonide

Producers of the drug: Orion Corporation ORION PHARMA 02200 Espoo, Finland, Pharmacor Production LLC

Composition

Each dose contains 0.2 mg of active substance - budesonide.

Additive: lactose monohydrate 7.8 mg



Form of issue

Budesonde is available in the form of a dosed powder for inhalation. One dose contains 200 μg (0.2 mg) of budesonide. In the cardboard bundle there is 1 inhaler of polymer material and 200 doses in laminated packages made of aluminum foil.

Therapeutic effect of the drug

Budesonide has a local antiexudative, immunosuppressive, anti-allergic and anti-inflammatory effect on the mucous membrane of the respiratory tract. The drug improves the control of the course of bronchial asthma. Asthma attacks can occur within 24 hours of the initiation of therapy with this drug. The maximum therapeutic effect is achieved after several weeks of continuous use of the drug.

Appointment of the drug

The drug is prescribed for bronchial asthma of mild, moderate and severe form. The inhaler is used as a safe therapy, with insufficient effect of beta20adrenostimulyatorov and ketotifen, as well as to reduce the dose of oral GCS.

Budesonide is accepted for the therapy of chronic obstructive pulmonary disease.

Intranasal preparation is used during seasonal or all-the-year-round rhinitis of an allergic nature.


Contraindications

  • Hypersensitivity or individual intolerance to the active substance, lactose and other excipients of the drug;
  • Diseases of respiratory organs of fungal origin;
  • Tuberculosis at the stage of activity;
  • Children's age till 6 years;

With extreme caution and only on the recommendation of a doctor prescribe the drug:

  • With cirrhosis of the liver;
  • With glaucoma;
  • Hypothyroidism;
  • With herpes lips and eyes;
  • Persons suffering from osteoporosis;
  • With diabetes mellitus;
  • With viral infections of the respiratory tract;
  • With hypertrophic obstructive cardiomyopathy;
  • Patients suffering from ischemic heart disease;
  • With chronic decompensated heart failure;
  • With severe form of hypertension;
  • During lactation;
  • At all stages of pregnancy;
  • With aneurysm;
  • With tachyarrhythmia;
  • With pronounced pheochromocytosis.

Instructions for use Budesonide

The regimen is prescribed by a specialist depending on the type of disease and age of the patient.

Usually inhaled budesonide is used by adults at 200-800 micrograms per day for 2-4 inhalations. Children older than 6 years take 1 inhalation (200 micrograms) per day, maximum allowed 2 inhalations per day.

Basic rules for using the inhaler:

  1. Open the packaging, store the can in the protective case;
  2. Shake the can and test spray the powder before use as directed;
  3. In the standing or sitting position, one must inhale through the mouthpiece deeply and actively (to receive the necessary dose of the substance in the bronchi);
  4. Do not exhale through the mouthpiece, but if this happens, you must tap the can on the hard surface carefully;
  5. Close the protective cover after the use of the inhaler has ended;
  6. Often clean the mouthpiece with a dry cloth. For purification use of water is strictly prohibited.

Caveats and Recommendations

When treating with Budesonide powder for inhalations, special instructions should be observed:

  • Avoid getting the drug in the eyes;
  • Children should be taken with caution and under the supervision of a doctor. High doses of the drug may slow the rate of growth and decrease hydrocortisone. It is recommended to monitor these indications;
  • After the application of budesonide, it is recommended to rinse the oral cavity with water to reduce the risk of candidal stomatitis;
  • When a dose is missed, inhalation should be applied as soon as possible, the remaining doses should be taken on the same day, sharing the intake at regular intervals;
  • Budesonide can not be exposed to direct sun rays or frozen. Observe all handling and disposal regulations;
  • When cooling the bottle, it is recommended to get it from the polymeric body and warm it in the hands, since at low temperatures the effectiveness of the drug decreases;
  • After discontinuation of the drug, a long observation of the patient and his respiratory function is necessary.

Side effects

In most cases Budesonide for inhalations is well tolerated by the body, but there are data on the appearance of such undesirable effects:

  • Tachycardia ;
  • tremor;
  • Muscle cramps ;
  • cough;
  • Headache and dizziness;
  • Irritation of the oral mucosa and pharynx;
  • Oral candidiasis;
  • anxiety;
  • hoarseness;
  • nausea;
  • sleep disturbance;
  • With increased sensitivity to the composition of the drug bruises and bruising arose;
  • In rare cases, itching, bronchospasm, depression, urticaria , cataracts, exanthema, increased pressure of the eyeball, stunted growth in children.

If they begin to disturb the above symptoms, then it is urgent to interrupt the treatment with budesonide and seek advice from a doctor.

An overdose of the drug

Toxic reactions in case of an overdose with budesonide are noted rarely. But with long-term use of the drug in high doses, a systemic reaction to glucocorticosteroids may develop:

  • Sensitivity to infections;
  • Development of hypercortisy;
  • Decreased adrenal function;
  • Atrophy of the cortex of the adolescents.

Compatibility of budesonide for inhalations with other drugs and alcohol

Information on the interaction of drugs with the inhalation form of budesonide is absent. Although it should be expected that Phenobarbital, Phenytoin, Rifampicin and other similar drugs reduce the effectiveness of Budesonide. The estrogens and methandrostenolone increase the action of budesonide.

Storage conditions and expiration dates

Budesonide for inhalations should be stored in a dry place away from children's access. The air temperature should not exceed 30 degrees Celsius. Protect the can from freezing or direct sunlight. Shelf life - 3 years from the date of release, after the discovery it is necessary to use the drug for 6 months.

Budesonide for inhalation analogues

Structural analogues of Budesonide powder for inhalation: Benacort, Pulmacort Turbuhaler, Cyclocaps, Tafen Novolayzer, Tsikortid, Novopulmon E Novolayzer.

Budesonide price

The average price of Budesonide powder for inhalation is 1100 rubles.

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