Budenit Steri-Neb user guide
Primary substance: budesonide 0.5 mg or 0.25 mg
Additional components: sodium chloride, citric acid, water for injection, sodium citrate.
Milk suspension, without a pronounced odor.
Pharmacological group: hormones of the adrenal cortex for topical application.
This drug has a pronounced anti-inflammatory and anti-allergic effect. Budesonide increases the formation of lipocardin, inhibits the release of blood through the vascular wall into the inflamed tissue.
Budesonide increases the sensitivity of the patient to drugs that relax the bronchial wall, which can reduce their intake or dose. Also reduces swelling of the bronchi, removes the inflammatory process, inhibits the formation of mucus.
It protects the bronchial mucosa from negative external influences, including respiratory infections. It is well tolerated even with prolonged therapy.
Therapeutic effect after the first application can be observed after a couple of hours. The maximum effectiveness of the drug will be achieved 10-12 days after the start of treatment. Helps to cope with the manifestation of bronchial asthma.
Absorption of the drug is fast enough, after the first inhalation bioavailability of 15-20% of the dose.
The main part is excreted through the kidneys, a little less through the intestines.
Half-life is about 3 hours.
Indications for use
The drug based on budesonide is prescribed for the following diseases:
- for the treatment of bronchial asthma, as a main therapy or as an additional drug for reducing the dose of oral agents;
- as a therapy for obstructive pulmonary disease.
Contraindicated under the following conditions:
- presence of an allergy to budesonide or other additional substances of the drug;
- contraindicated for children up to 12 months.
With extreme caution to take with: pulmonary tuberculosis, fungal infections, bacterial type, during pregnancy and lactation.
Pregnancy and breastfeeding
The use of the drug during pregnancy is allowed when the risk to the fetus is minimal or absent, i. E. The benefits exceed the possible negative effects. Also, during the period of gestation, the minimum dose of this medication is recommended. Whether budesonide is able to penetrate into breast milk is not established.
Mode of application
Budenitis Steri-neb is inhaled inhaler.
In the treatment of bronchial asthma or with the cancellation of oral medications, the following doses are recommended:
- Adults, elderly people and children over 12 years of age take 1-2 mg of the drug 2 times a day. The dose for maintenance can be from 1 mg to 4 mg per day.
- Children from 1 year to 12 years: 0.25 mg or 0.5 mg 2 times a day. The maintenance dose is not more than 2 mg of the drug per day.
The maintenance dose is selected individually for each patient, depending on the complexity of the disease. When the therapeutic effect is achieved, the maintenance dose is reduced to a minimum, provided that the patient has no symptoms.
To improve the effect of therapy Budenit Steri-Neb, its dose can be increased, but in this case, oral intake should be canceled.
The drug Budenit Steri-Neb can cause the following side effects:
- dryness of the mucous membrane of the pharynx;
- a slight cough;
- change in taste;
- hoarseness of voice.
In more rare cases, the occurrence may occur: sleep, nervousness, urticaria, headache, redness and rash on the skin.
With prolonged treatment with large doses, there may be increased side effects. Children may experience growth retardation or a malfunction in the hormones of the adrenal cortex.
In most cases, an overdose of the drug does not occur. In case of side effects or overdose - the drug is canceled, prescribe funds with a short bronchodilating effect.
Interaction with other medicinal products
Budenit Steri-Neb is allowed to mix with 0.9% sodium chloride solution.
When taking antifungal preparations of imidazole derivatives, the concentration of budesonide in the blood increases. However, this effect can not be attributed to inhalant forms of the drug, as today there have been no similar studies.
Medications related to left-side anabolic steroids and estrogens can significantly enhance the effect of Budenit Steri-Neb.
It was noted that the therapeutic effect of the medicine comes within 10-12 days. If the patient suffers from increased mucus secretion, then oral therapy with a duration of 10-14 days can be previously performed. Further, it is possible to prescribe GCS in inhalers.
Before transferring the patient from oral treatment to Budenit Steri-Neb, it is necessary to ensure the stability of the patient's condition.
In some cases, after transferring to the Budenite Steri-Neb, muscle pain, fatigue or a headache was observed. Such symptoms can occur by themselves or cause a temporary increase in the oral dose of GCS.
After each use of the inhaler, rinse the mouth with water or chamomile to avoid the occurrence of fungal stomatitis.
Avoid contact with eyes.
Form of issue
Suspension for inhaler (inhalation) of 0.25 mg or 0.5 mg.
Produced in an ampoule of 2 ml.
Keep in a cool and dark place out of the reach of children.
Shelf life 2 years from the date of manufacture.
It is released strictly according to the prescription of the attending physician.
Reviews about the drug
The drug received a lot of positive feedback about its effectiveness. Patients claimed that the therapeutic effect comes quickly, does not cause side effects. Plus, it is also that Budenit Steri-Neb can be taken by children from 1 year old.
The minus of the drug was attributed to its high cost and the fact that the drug is hormonal.
Budenit Steri-Neb price
Budenit Steri-Neb suspension for inhalations of 0.25 mg / ml 2ml № 20 - 700-760 rub.