Budenit Steri-Neb instructions for use
Base material: budesonide 0.5 mg or 0.25 mg
Additional components: sodium chloride, citric acid, water for injection, sodium citrate.
Suspension milky, no pronounced smell.
Pharmacological group: adrenal cortex hormones for local use.
This drug has a pronounced anti-inflammatory and antiallergic effect. Budesonide increases lipocartine formation, inhibits the release of blood through the vascular wall into the inflamed tissue.
Budesonide increases the patient's sensitivity to drugs that relax the bronchial wall, which reduces their intake or dose. Also reduces swelling of the bronchi, relieves inflammation, inhibits the formation of mucus.
It protects the bronchial mucosa from negative external influences, including infections of the respiratory type. Well tolerated even with long-term therapy.
The therapeutic effect after the first application can be observed after a couple of hours. The maximum effectiveness of the drug will be achieved in 10-12 days after the start of treatment. Helps to cope with the manifestation of bronchial asthma.
Absorption of the drug is quite fast, after the first inhalation bioavailability of 15-20% of the dose.
The main part is excreted through the kidneys, a little less through the intestines.
The half-life is about 3 hours.
Indications for use
The drug on the basis of budesonide is prescribed for the following diseases:
- for the treatment of bronchial asthma, as a primary therapy or as an additional drug to reduce the dose of oral agents;
- as therapy for obstructive pulmonary disease.
Contraindicated in the following conditions:
- allergy to budesonide or other additional drug substances;
- contraindicated in children up to 12 months.
Take extra caution when: pulmonary tuberculosis, fungal infections, bacterial type, during pregnancy and lactation.
Pregnancy and breastfeeding
The use of the drug during pregnancy is permitted when the risk to the fetus is minimal or absent, i.e. the benefits outweigh the possible negative effects. Also, during the gestation period, a minimum dose of this medicine is recommended. Whether budesonide is able to penetrate into breast milk has not been established.
Mode of application
Budenitis Steri-Neb is taken by inhalation using an inhaler.
When treating bronchial asthma or withdrawing oral agents, the following doses are recommended:
- Adults, the elderly and children over 12 years old take 1-2 mg of the drug 2 times a day. The maintenance dose may be from 1 mg to 4 mg per day.
- Children from 1 year to 12 years: 0.25 mg or 0.5 mg 2 times a day. Maintenance dose of no more than 2 mg of the drug per day.
Maintenance dose is selected individually for each patient, depending on the complexity of the disease. When the therapeutic effect is reached, the maintenance dose is reduced to the minimum, provided that the patient has no symptoms.
To improve the effect of therapy with Budenit Steri-Neb, its dose can be increased, but in this case, oral administration should be canceled.
Budenit Steri-Neb may cause the following side effects:
- dry pharyngeal mucosa;
- slight cough;
- change in taste;
In more rare cases, the occurrence of: sleep disturbance, nervousness, urticaria, headache, redness and rash on the skin.
With long-term treatment with large doses, increased side effects may occur. Children may experience stunted growth or failure of the adrenal cortex hormones.
In most cases, drug overdose does not occur. In the event of side effects or overdose - the drug is canceled, prescribe funds with a short bronchodilator effect.
Interaction with other drugs
Budenit Steri-Neb is allowed to mix with 0.9% sodium chloride solution.
When taking antifungal preparations of imidazole derivatives, the concentration of budesonide in the blood increases. However, such an effect cannot be attributed to inhaler forms of the drug, as there has been no similar research to date.
Drugs for left-sided anabolic steroids and estrogens can significantly enhance the effect of Budenit Steri-Neb.
It was noted that the therapeutic effect of the drug occurs within 10-12 days. If the patient suffers from an increased secretion of mucus, then oral therapy can be preformed for a duration of 10-14 days. Further, it is possible to appoint GKS in inhalers.
Before transferring a patient from oral treatment to Budenit Steri-Neb, it is necessary to make sure that the patient’s condition is stable.
In some cases, after transferring to Budenit Steri-Neb, muscle pain, fatigue or headache was observed. Such symptoms can go away by themselves or cause a temporary increase in the oral dose of GCS.
After each use of the inhaler, it is necessary to rinse the mouth with water or chamomile, in order to avoid the occurrence of fungal stomatitis.
Avoid contact with eyes.
Suspension for inhaler (inhalation) at 0.25 mg or 0.5 mg.
Available in 2 ml ampoule.
Store in a cool and dark place out of the reach of children.
Expiration date 2 years from the date of manufacture.
It is released strictly according to the prescription of the attending physician.
The drug received a lot of positive feedback about its effectiveness. Patients claimed that the therapeutic effect comes quickly, does not cause side effects. A plus is also the fact that Budenit Steri-Neb can be taken by children from 1 year old.
By cons of the drug was attributed to its high cost and the fact that the agent is hormonal.
Budenit Steri-Neb Price
Budenit Steri-Neb suspension for inhalation 0.25 mg / ml 2 ml № 20 - 700-760 rub.