Bromhexin 8 Berlin-Chemie user manual
Dragee Bromgexin 8 Berlin-Chemie is a known remedy with a small antitussive and powerful expectorant, as well as mucolytic action. Significantly reduces the viscosity of contained sputum in the bronchi. The drug is designed to quickly improve sputum discharge and increase its volume. The effect of the application comes after 2 - 5 days. With the parallel administration of the drug with antibiotics, their concentration in the mucrotic secretions increases. After oral administration of bromhexine, it is rapidly absorbed. The components of the drug do not accumulate in the human body. Bromhexine is able to penetrate the milk of lactating women and into the placenta during pregnancy.
Form of issue and composition
Bromhexine 8 Berlin-Chemie is available in the form of a pellet with an active ingredient of bromhexine hydrochloride 8 mg. The blister contains 25 tablets. It is packed in a cardboard box, which also has instructions for this preparation. In addition to the active ingredient, the composition includes additional components represented by corn starch, lactose monohydrate, sucrose, glucose syrup, magnesium stearate, macrogol 6000, titanium dioxide, talc and some other auxiliaries.
Indications for use
The drug should be administered in such painful conditions:
- Diseases of the bronchi, as well as of the lungs, which occur both in chronic and acute form;
- Formation in the bronchi of sputum, which have a difficult to separate consistency and is poorly excreted from the body.
This medication should not be prescribed in the presence of these diseases:
- Presence of any reactions of hypersensitivity to the main active ingredient or to any additional substance;
- The period of breastfeeding;
- State of pregnancy.
There are some limitations. Relative contraindications can be considered:
- Diseases of the respiratory system, in which there is an excessive accumulation of bronchial secretions;
- Peptic ulcers in the organs of the digestive tract;
- Hepatic and renal diseases.
Dosing and Administration
As a dragee, Bromhexine 8 Berlin-Chemie should be taken only after meals, while washing them with a sufficient volume of liquid. In pediatrics: children, whose age does not exceed 6 years, as well as patients with a body weight of up to 50 kg, should take 4-8 mg of Bromhexine 8 Berlin-Chemie 3 times per day. The daily dose in this case should be from 12 to 24 mg of bromhexine per day. Up to 6 years, it is better not to use the form of the agent in the form of a dragee. Dosage for children of the 6-14 age group is recommended at 8 mg three times a day. Adolescents from 14 years old, as well as adults, need to take 1 or 2 tablets 3 times a day. The course of therapy should be set individually. It depends on the severity of the manifestations of the underlying disease and the observed effect of the therapy. Without medical advice, Bromgexin 8 Berlin-Chemie should not be consumed for more than 5 days. The dose should be reduced if the patient has a history of severe liver disease or kidney failure.
There may be allergic manifestations of varying severity: skin itch accompanied by a rash (usually in the form of urticaria), febrile conditions, malfunction in the work of respiratory function, angioedema edema, sudden appearance of bronchospasm. Anaphylactic shock can be observed very rarely. Sometimes the drug causes nausea and unexplained pain in the epigastric region, diarrhea, various dyspeptic manifestations. The analysis of blood may increase the activity of aminotransferases. In individual cases, the development of Lyell's syndrome and Stevens-Johnson syndrome is possible.
When Bromgexin 8 is administered to Berlin-Chemie patients who have a history of peptic ulcer of the gastrointestinal tract or bleeding, caution is required. The sudden or gradual development of any changes on the skin requires immediate withdrawal of the selected therapy with bromhexine. Also, special attention is paid to people with violations of bronchial motility, which produce an increased amount of sputum viscous consistency. Reducing the dosage of Bromhexine 8 Berlin-Chemie or increasing the gap between medication is needed for patients with kidney disease or liver damage. If a long course is required, it is important to periodically conduct laboratory monitoring of the biochemical parameters of the patient's blood. Contraindicated bromheksin with a known intolerance to fructose, malabsorption syndrome. In nursing women and women bearing a child, the drug is taken strictly after the benefit-risk relationship. Reception dragee is recommended from the age of 6 years. The agent has no effect on the reaction rate when controlling complex mechanisms.
The drug Bromhexine 8 Berlin-Chemie, when used with medicinal substances that have an irritant ability on the gastric mucosa, enhances this effect. The combination with antitussive substances is not allowed because of the possible development of sputum stagnation in the bronchi due to the pronounced suppression of the cough reflex. When bromhexine is combined with various antibiotics, they penetrate more fully into the lung tissue.
Data on overdose are unknown. It can indicate such symptoms: vomiting, metabolic acidosis, double vision. In the treatment it is necessary to constantly control the work of the heart, to carry out therapy aimed at the maximal relief from symptoms.
Bromhexine 8 Berlin-Chemie analogues
Bromhexine 8 Berlin-Chemie has many analogues. This drug can be found under the name "Bromgexin" in different dosages, manufactured by various manufacturers. Solvin and Bronchohex are also analogues.
Terms and conditions of storage
It is allowed to store in a dry place, which is well ventilated, at a temperature of 15 to 30 degrees. The expiration date is 5 years.