The Brizantine tablets: instruction manual, price, reviews, analogs of tablets Brizantine
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Brizantine tablets instructions for use

The drug Brizantine is a combined drug that is used to treat nicotine dependence. This drug restores homeostasis (constancy of the internal environment) and improves the functional activity of the brain in conditions of withdrawal from nicotine. Stimulates the cannabidine receptors of the central nervous system.

Form of issue and composition

Brizantine is available in the form of tablets for resorption. The composition of one tablet includes several active ingredients, which include:

  • Affinely purified antibodies to the brain-specific protein S-100 (they are sorbed into lactose molecules in several dilutions of alcohol solution) - 0.006 g.
  • Affinely purified antibodies to cannabinoid receptor type 1 - 0.006 g.

Also included in the formulation are lactose auxiliaries, magnesium stearate, microcrystalline cellulose. Tablets are packaged in a cardboard package of 40 pieces, and it also contains instructions for the use of the drug.

pharmachologic effect

Resorption tablets Brizantine is a combined drug that is used in the treatment of nicotine addiction. It contains two active substances - affinity purified antibodies to the brain-specific protein S-100 and antibodies to the cannabinoid receptor type 1. They have various therapeutic effects on the central nervous system and the cerebral cortex, which include:

  • Neuroprotective - a protective effect on neurocytes (neurons) under the conditions of their adjustment to the functioning without nicotine.
  • Antioxidant - bind free radicals, whose molecules have an unpaired electron in their structure, therefore possess high chemical activity and destroy the structures and cellular membrane of the neurocytes.
  • Antihypoxic - improve energy processes in neurocytes and increase their resistance to insufficient oxygen.
  • Improving the transmission of the nerve impulse in the synapses of various structures of the brain, which was disrupted by the systematic introduction of nicotine into the body.
  • Membranotropic action - suppress the generation of excessive amounts of nerve impulses in neurocytes.
  • Increase the inhibitory effect of gamma-aminobutyric acid in the cerebral cortex, thereby reducing the feeling of discomfort, anxiety and tension during the process of weaning from nicotine.

These pharmacological effects are realized by modulating the S-100 protein and cannabinoid receptors in the limbic system of the brain. The drug stimulates the functioning of the limbic system, improves the positive mood, which helps to reduce the intensity of craving for psychoactive substances, in particular nicotine. Also, the pills reduce the intensity of emotional symptoms of withdrawal from nicotine - irritability, depression, decreased mood, internal discomfort. This leads to a decrease in the number of cigarettes smoked during the day. The drug does not have carcinogenic properties and its administration does not lead to weight gain.

In connection with the inability to accurately determine the low concentrations of the active substances of the Brizantine tablets, the pharmacokinetics of the drug remains insufficiently studied.

Indications for use

The use of Brizantine tablets is indicated to reduce symptoms of withdrawal symptoms during quitting (treatment of nicotine addiction). Their use is possible in the first hours and days of quitting. Also, the drug is effective in reducing the psychological imperative desire to smoke after a significant period of time after quitting.

Contraindications for use

The only absolute contraindication to the use of tablets for resorption of Brizantine is an individual intolerance or hypersensitivity to the main active substances or components of the drug. Also, due to the lack of reliable data on possible harm, the drug is not used for children under the age of 16, pregnant or lactating women. If necessary, use is possible for pregnant women, after assessing the ratio of the likelihood of expected benefit to the mother and the potential risk to the developing fetus.

Dosing and Administration

During the treatment of nicotinic dependence, the Bryzantine tablets dissolve (the tablet should be in the oral cavity until complete resorption). The average dose is 2-3 tablets per day. With a strong, imperative desire to smoke, resorption of 5-6 tablets during the day is allowed. As the symptoms of weaning decrease, the dose is reduced. The recommended course of use of the drug is 3 months.

Side effects

Pills for resorption Brizantine are well tolerated. Sometimes there are reactions of individual intolerance or hypersensitivity to the components of the drug in the form of skin rashes, nausea, or vomiting.

special instructions

Before you start using the drug, you should carefully study its instructions. The composition of the drug includes lactose, so with caution it is used for people with lactase deficiency, malabsorption syndrome, congenital galactosemia or other pathological conditions accompanied by an insufficient amount of lactase enzyme (responsible for digestion and digestion of lactose in the digestive tract). Brizantine tablets do not affect the speed of psychomotor reactions and concentration of attention. They also do not interact with drugs from other pharmacological groups. In pharmacies, the drug is dispensed without a prescription. In case of doubt or questions, consult a physician.


If the recommended therapeutic dose is significantly exceeded, nausea, vomiting, and abdominal pain may develop. In this case, the drug is stopped. If necessary, symptomatic therapy is performed.

Brizantine analogues

A similar pharmacological action is possessed by the drug Tabex.

Terms and conditions of storage

Shelf life of the resorption tablets is 3 years from the date of manufacture. Keep the drug in a dark place inaccessible to children at an air temperature of no higher than 25 ° C.

Brizantine price

Brizantine tablets for resorption, 40 pcs. - 280-350 rub.

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