Britomar instructions for use
Britomar tablets of the Spanish pharmaceutical company Ferrer Internationale are a highly effective diuretic. It has a prolonged action, which allows its reception only once a day. However, in order to avoid side effects, the correct dosage should be selected at a time, and only a doctor will help with this. Read the instructions to the drug below.
Release form and composition
Britomar tablets can be presented in a pharmacy in two different dosages, which differ in the amount of the active substance - torasemide.
There are tablets containing 5 mg of torasemide. In addition to this substance, they contain auxiliary components:
- colloidal silicon dioxide - 0.42 mg;
- guar gum - 3.4 mg;
- corn starch - 30.77 mg;
- lactose monohydrate - up to 85 mg;
- magnesium stearate - 0.25 mg.
Britomar 10 mg contains 10 mg of torasemide, 0.85 mg of colloidal silicon dioxide, 6.8 mg of guar gum, 0.51 mg of magnesium stearate, corn starch - 61.54 mg and lactose monohydrate to 170 mg.
Britomar tablets have almost white or white color, biconvex, round shape, engraving "SN" on one side.
The drug has a prolonged action.
Tablets are packaged in blisters of 15 pieces, which in turn are packaged in one or two blisters in cardboard boxes and supplied with instructions.
Indications for use
Britomar is prescribed for arterial hypertension, as well as for edema syndrome. The latter can be of any origin: in diseases of the kidneys, liver or heart failure.
The active ingredient torasemide refers to loop diuretics, which, by contacting the chlorine / sodium / potassium ion transporter, reduces water rearbsorption and the osmotic pressure of the intracellular fluid.
About an hour after taking the drug, a diuretic effect is observed, which reaches a maximum mark in 3-6 hours. The action of Britomar tablets lasts from 8 to 10 hours.
The medicament Britomar not prescribed for anuria, dehydration precoma and coma liver, disturbances of the flow of urine various reasons (including the unilateral urinary tract lesion), refractory hyponatremia and hypokalemia, acute glomerulonephritis, digitalis intoxication, sinoatrial and atrioventricular block 2 and 3 degrees , lactase deficiency, glucose-galactose malabsorption, galactose intolerance, hypersensitivity to the drug.
This drug is contraindicated for pregnant women and children under 18 years of age, as well as for persons with allergies to sulfonylamides.
By following the necessary precautions Britomar assigned hypovolemia, ventricular arrhythmia history, hypotension, acute myocardial infarction, tackle urinary outflow, diarrhea, diabetes, pancreatitis , various liver diseases (which may be complicated by hepatorenal syndrome, renal insufficiency, ascites or cirrhosis a), anemia, hyponatremia, hyperuricemia, hypokalemia, gout, simultaneous use of aminoglycosides, corticosteroids, cardiac glycosides, cephalosporins, adrenocort Icotropic hormone.
During lactation, the drug is used with caution.
Dosing and Administration
Tablets are prescribed inside, without chewing, entirely, washing down with a sufficient amount of liquid. You can take them at any time, regardless of the meal.
The dosage of the drug will vary depending on the disease:
- In chronic heart failure (edematous syndrome) - 10-20 mg once a day; if necessary, the doctor can double the dose;
- For kidney disease (edematous syndrome) - 20 mg once a day; the doctor may prescribe a double dose if necessary;
- In case of liver diseases (edematous syndrome) - 5-10 mg once a day together with potassium-sparing diuretics or aldosterone antagonists; a double dose of the drug may be prescribed if indicated;
- With hypertension - 5 mg once a day; if the blood pressure is not reduced, the dosage can be increased to 10 mg per day, if necessary, an additional antihypertensive drug is assigned that belongs to another group.
For elderly patients there is no need to adjust the dosage.
A single dose of 40 mg is not recommended to exceed, since there is no reliable data on its effectiveness.
If the dosage was missed, there is no need to take a double volume of the drug. You just need to use the missed pill, and the next one - at the usual time.
Among the side effects often occur dizziness, drowsiness, headache, diarrhea, increased urination, nocturia and polyuria.
Infrequently a patient when taking Brimara complain of cramping of the lower limb muscles, hypertriglyceridemia, increased thirst, hypercholesterolemia, arrhythmias, flushing, palpitation, tachycardia, nasal bleeding, bloating, abdominal pain, frequent urination, increasing the number of platelets in the blood , fatigue, exhaustion, nervousness, weakness, hyperactivity, thirst.
The following side effects are quite rare:
- numbness and tingling in the limbs;
- deep vein thrombosis;
- vomiting and nausea;
- loss of appetite;
- dyspeptic symptoms;
- increased creatine and urea in the blood;
- urine retention;
- hyperglycemia and hyponatremia;
- decrease in the number of leukocytes, erythrocytes and platelets;
- metabolic alkalosis;
- tinnitus and hearing loss;
- visual impairment;
- rash and pruritus.
For any negative effects while taking Britomar tablets, you should consult with your doctor, who will adjust the dosage or suggest another drug.
Britomar tablets can be used only after consulting a doctor.
If patients have an increased sensitivity to sulfonylurea derivatives and sulfonamides, then it can also manifest itself in relation to this drug.
Before starting treatment, especially in the elderly, it is necessary to monitor the concentration and volume of circulating blood, as well as electrolyte balance. If the treatment is carried out for a long time, such monitoring must be done constantly. In addition, the levels of uric acid, glucose, cellular blood components, lipids and creatinine are checked.
Patients who take Britomir for a long time and in large doses, there is no need to limit the use of salt. Such a measure will avoid the development of alkalosis and hyponatremia.
The development of hypokalemia is most susceptible to patients with diuresis, cirrhosis of the liver, taking ACTH and corticosteroids, as well as with limited consumption of electrolytes with food.
Patients with renal insufficiency may develop disorders with water and electrolyte balance. To avoid this, it is necessary to continuously monitor the concentration of electrolytes in the blood plasma, residual nitrogen, acid-base balance, creatinine and uric acid levels. If necessary, the doctor will prescribe a corrective course of treatment.
In the case of severe violations in the patient's body, which were identified by blood tests, it is necessary to completely stop taking Britomar. After the restoration of normal indications, the doctor will install a lower dosage of the drug. If oliguria increases or is manifested, azotemia in patients with kidney disease should be stopped.
For patients suffering from ascites with cirrhosis of the liver, the dosage of the drug is selected in the hospital. For such patients, constant monitoring of the level of electrolytes in the blood plasma is necessary.
In order not to develop hypokalemia, it is necessary to prescribe an additional potassium-sparing diuretics (spironalactone), potassium preparations, and also recommend adhering to a diet rich in potassium.
Britomar tablets can cause an exacerbation of gout.
Patients with diabetes need to control the level of glucose in the urine and blood.
Ballroom sufferers with ureteral narrowing and prostatic hyperplasia need control of duresis.
Britomar may cause arrhythmias in persons with cardiovascular problems, as well as those receiving cardiac glycosides.
During treatment, care must be taken by persons whose activity is related to quick response and increased attention.
Terms and conditions of storage
Tablets should be stored in a place protected from sunlight at room temperature up to + 30 ° C. The drug should be in a restricted place for children. Valid Britomar within 3 years from the date of manufacture.
Pharmacy vacation terms
Britomar tablets are sold from pharmacies by prescription.
The following drugs are related to Britomar tablets:
- Torasemid Canon;
Britar tablets 5mg - 330-390 rubles.
Britomar tablets 10 mg - 400-470 rubles.