Britomar instructions for use
The Britomar tablets of the Spanish pharmaceutical company Ferrer International are a highly effective diuretic. It has a prolonged action, which allows you to take it only once a day. However, in order to avoid side effects, the correct dosage should be chosen at the same time, and only the doctor will help with this. You can read the instructions to the drug below.
Form of issue and composition
Britomar tablets can be presented in a pharmacy in two different dosages, which differ in the amount of active ingredient - torasemide.
There are tablets containing 5 mg of torasemide. In addition to this substance, they include auxiliary components:
- Colloidal silicon dioxide - 0.42 mg;
- Guar gum - 3,4 mg;
- Corn starch - 30.77 mg;
- Lactose monohydrate - up to 85 mg;
- Magnesium stearate 0.25 mg.
Brithmore 10 mg contains 10 mg of torasemide, 0.85 mg of colloidal silicon dioxide, 6.8 mg of guar gum, 0.51 mg of magnesium stearate, corn starch - 61.54 mg and lactose monohydrate up to 170 mg.
Britomar tablets have almost white or white color, biconvex, round shape, engraving "SN" on one side.
The drug has a prolonged action.
Packed tablets in blisters of 15 pieces, which in turn are packed one or two blisters in cardboard boxes and supplied with instructions.
Indications for use
Britomar is prescribed for arterial hypertension, as well as for edematic syndrome. The latter can be of any origin: in diseases of the kidneys, liver or heart failure.
The active substance torasemide refers to loop diuretics, which, when bound to the chlorine / sodium / potassium ion transfer contractor, reduces water reabsorption and osmotic pressure of the intracellular fluid.
Approximately one hour after taking the drug, a diuretic effect is observed, which reaches a maximum mark in 3-6 hours. The action of Britomar tablets lasts from 8 to 10 hours.
The drug Britomar is not prescribed for anuria, dehydration, precoma and coma of the liver, violations of urinary drainage of various causes (including unilateral urinary tract damage), refractory hyponatremia and hypokalemia, acute glomerulonephritis, digitalis intoxication, sinoatrial and atrioventricular block 2 and 3 degrees , Deficiency of lactase, glucose-galactose malabsorption, galactose intolerance, hypersensitivity to the components of the drug.
This drug is contraindicated in pregnant women and children under 18 years old, as well as persons with allergies to sulfonylamides.
Following proper precautions, Britomar is prescribed for hypovolemia, ventricular arrhythmia in history, arterial hypotension, acute myocardial infarction, impaired urine outflow, diarrhea, diabetes mellitus, pancreatitis , various liver diseases (which can be complicated by hepatorenal syndrome, renal failure, ascites or cirrhosis ), Anemia, hyponatremia, hyperuricemia, hypokalemia, gout, concomitant use of aminoglycosides, corticosteroids, cardiac glycosides, cephalosporins, adrenocortex Icotrope hormone.
During the lactation period, the drug should be used with caution.
Dosing and Administration
Tablets are administered orally, without chewing, wholly, with a sufficient amount of liquid. You can take them at any time, regardless of food intake.
The dosage of the drug will differ depending on the disease:
- With chronic heart failure (edematous syndrome) - 10-20 mg once a day; If necessary, the doctor can increase the dose twice;
- With kidney diseases (edematic syndrome) - 20 mg once a day; The doctor may prescribe a double dose if necessary;
- With liver diseases (edematous syndrome) - 5-10 mg once a day in conjunction with potassium-sparing diuretics or aldosterone antagonists; Can be prescribed a double dose of the drug according to the indications;
- With arterial hypertension - 5 mg once a day; If the blood pressure is not reduced dosage can be increased to 10 mg per day, if necessary, an additional antihypertensive drug is assigned to another group.
For elderly patients, there is no need to adjust the dosage.
A single dose of 40 mg is not recommended to be exceeded, as there is no reliable data on its effectiveness.
If dosage has been missed, there is no need to take a double volume of the drug. Just need to use the missed pill, and the next - at the usual time.
Side effects include dizziness, drowsiness, headache, diarrhea, frequent urination, nocturia, and polyuria.
Infrequently, the patient, when taking Brimar, complains of cramps of the muscles of the lower extremities, hypertriglyceridemia, increased thirst, hypercholesterolemia, extrasystole, redness of the face, increased heart rate, tachycardia, nosebleeds, flatulence, abdominal pain, frequent urge to urinate, increased platelets in the blood , Increased fatigue, exhaustion, nervousness, weakness, hyperactivity, thirst.
The following side effects are rare:
- Numbness and tingling in the limbs;
- Arterial hypotension;
- Deep vein thrombosis;
- Vomiting and nausea;
- loss of appetite;
- Dyspeptic phenomena;
- Increase of creatine and urea in the blood;
- Retention of urine;
- Hyperglycemia and hyponatremia;
- Decrease in the number of leukocytes, erythrocytes and platelets;
- Metabolic alkalosis;
- Ringing in the ears and hearing loss;
- Impaired vision;
- Rash and itchy skin.
In case of any negative effects during taking Britomar tablets, it is necessary to consult a doctor who will adjust the dosage or suggest another medication.
Britomar tablets can be taken only after consultation with a doctor.
If patients have a hypersensitivity to sulfonylurea derivatives and sulfonamides, it can also appear in relation to this drug.
Before starting treatment, especially in the elderly, it is necessary to monitor the concentration and volume of circulating blood, as well as electrolyte balance. If treatment is carried out for a long time, such control must be done constantly. In addition to this, check the level of uric acid, glucose, cellular components of blood, lipids and creatinine.
The patient who takes Britomir for a long time and in large doses, there is no need to limit the intake of table salt. Such a measure will avoid the development of alkalosis and hyponatremia.
The development of hypokalemia is most affected by patients with diuresis, cirrhosis of the liver, taking ACTH and corticosteroids, as well as with limited consumption of electrolytes with food.
In patients with renal insufficiency, violations with a water-electrolyte balance can develop. To avoid this, you must constantly monitor the concentration of electrolytes in blood plasma, residual nitrogen, acid-base balance, the level of creatinine and uric acid. If necessary, the doctor will prescribe a corrective course of treatment.
In the case of severe disorders in the patient's body, which were identified by means of blood tests, it is necessary to completely stop receiving Britomar. After restoring normal indications, the doctor will establish a lower dosage of the drug. If oliguria is intensified or manifested, azotemia in patients with kidney diseases should be stopped.
For patients suffering from ascites with cirrhosis of the liver, the dosage of the drug is selected in a hospital. For such patients, continuous monitoring of the electrolyte level in the blood plasma is necessary.
In order not to develop hypokalemia, it is necessary to prescribe additionally potassium-sparing diuretics (spironolactone), potassium preparations, and also to recommend adherence to a diet rich in potassium.
Britomar tablets can provoke an exacerbation of gout.
Patients with diabetes need to control the level of glucose in the urine and blood.
Ballroom suffering narrowing of the ureter and hyperplasia of the prostate gland requires control of the dura.
Britomar can cause arrhythmia in people with cardiovascular problems, as well as taking cardiac glycosides.
During treatment, care must be taken for individuals whose activities are associated with a rapid reaction and increased attention.
Terms and conditions of storage
Tablets should be stored in a place protected from sunlight, at room temperature up to + 30 ° C. The drug should be in a place that is limited to children. Goodman is a Brotomar for 3 years from the date of manufacture.
Terms of leave from the pharmacy
Britomar tablets are sold from pharmacies on prescription.
Analogs of tablets Britomar include the following drugs:
- Torasemide Canon;
Britomar tablets 5 mg - 330-390 rub.
Britomar tablets 10 mg - 400-470 rub.