Binelol instructions for use
- Binelol instructions for use
- Release form and composition of the drug
- Pharmacological properties of the drug
- Indications for use
- Dosage and administration
- Use of the drug during pregnancy and lactation
- Side effects
- In rare cases, the patient may develop bronchospasm.
- Interaction with other drugs
- special instructions
- Conditions of storage and release of the drug
- Binafin analogues
- Binafin price
The drug Binelol belongs to the group of beta-blockers, whose therapeutic effect is to eliminate violations of the cardiovascular system, blood pressure indicators, prevention of stroke in patients at risk.
Release form and composition of the drug
The drug Binelol is available in the form of white tablets, with a notch in the form of a cross on one side. Each tablet contains 5 mg of the active active ingredient - nebivolol hydrochloride and auxiliary components.
Pharmacological properties of the drug
When ingested, the main active ingredient of the drug is rapidly absorbed through the mucous membranes of the gastrointestinal tract and enters the general bloodstream. The drug has a pronounced hypotensive property, eliminates the phenomenon of cardiac arrhythmia, normalizes the activity of the cardiovascular system. Patients noted that with the regular use of tablets of this drug, the symptoms of hypertension disappeared, and not only in a state of complete rest, but also during exercise.
The main active ingredient of the drug has a mild vasodilator property, which favorably affects the work of the central nervous system and the brain in particular. Regular use of this drug eliminates strokes and prevents the development of ischemic stroke or myocardial infarction. In these cases, patients are better tolerated exercise and any excitement.
Indications for use
Binelol tablets prescribe a patient with a therapeutic and prophylactic purpose for such conditions:
- Severe arterial hypertension;
- As part of complex therapy for diagnosed heart failure;
- Coronary heart disease;
- As part of complex therapy in atherosclerosis of the cerebral arteries;
- Prevention of attacks of stenocardia and myocardial infarction in patients at risk (overweight, smokers, patients whose cases were cases of heart attack, ischemic stroke).
Binelol tablets are contraindicated in patients with such conditions and pathologies:
- Disorders in the liver and kidneys in the stage of decompensation;
- Myocardial infarction, accompanied by cardiogenic shock;
- Acute heart failure, as well as failure of the chronic course in the stage of decompensation;
- Bronchial asthma or bronchial obstruction;
- Prolonged depression with suicidal tendencies;
- Untreated pheochromocytoma;
- The change in blood pH in the acidic side;
- Low blood pressure;
- Myasthenia gravis;
- Individual intolerance to the components of the drug;
- Raynaud's disease;
- Age up to 18 years;
- Lactase deficiency or complete lactose intolerance.
This drug should be used with caution in patients with diabetes mellitus and other diseases of the organs of the endocrine system, psoriasis, systemic blood diseases, burdened with an allergic history, chronic obstructive pulmonary disease, as well as elderly patients.
Dosage and administration
The drug Binelol is intended for oral administration. The pill should be taken strictly at one and the same time 1 time per day, regardless of meals. The drug is not chewed and washed down with a sufficient amount of water.
The daily dose of the drug is determined by the doctor, depending on the diagnosis, the severity of the clinical symptoms of the disease, the presence of concomitant pathologies and the individual characteristics of the patient. The initial therapeutic dose of Binelol is 2.5 mg per day; this dosage is no longer increased in patients with hepatic impairment. In the absence of a therapeutic effect or the presence of concomitant serious diseases, the daily dose of the drug to patients who do not have abnormalities in the liver can be increased to 10 mg. The duration of the course of therapy is determined by the doctor.
Use of the drug during pregnancy and lactation
In the first trimester of pregnancy, this drug is not prescribed to women due to the lack of reliable data on its safety for the intrauterine development of the fetus.
In the second and third trimesters of pregnancy, drug treatment is possible only if there are serious indications and if the potential benefit to the mother is higher than the likely harm to the fetus.
Treatment with the drug shortly before birth increases the risk of developing bradycardia and paralysis of the respiratory tract in a newborn baby, therefore, about one week before the expected date of birth, Binelol therapy should be interrupted.
Studies on animals have shown that the active ingredients of the drug easily penetrate into breast milk and are passed to the child, so if a woman needs to undergo a course of treatment with Binelol, then breastfeeding will have to stop.
The drug is generally well tolerated, but with increasing patient dose or uncontrolled long-term use, side effects quickly develop:
- On the part of the nervous system: dizziness and headaches, increasing weakness, drowsiness, in rare cases depression, decreased concentration, convulsions , paresthesias;
- On the part of the digestive canal organs: abdominal pain, constipation, increased gas formation, nausea, dry mouth;
- From the side of the heart and blood vessels: the development of acute heart failure, bradycardia, shortness of breath, weakening of the pulse, a sharp decrease in blood pressure, heart pain;
- Allergic skin reactions - erythema, itchy skin;
In rare cases, the patient may develop bronchospasm.
With an overdose of the drug, the above phenomena appear acute. To the listed symptoms adds cyanosis of the limbs, cardiac arrhythmias, cardiogenic shock, loss of consciousness, coma.
With the development of similar symptoms of drug overdose, the patient should lie down with a raised foot end, give activated carbon or another enterosorbent to drink, and call an ambulance.
Treatment of an overdose with beta-blockers is gastric lavage and symptomatic therapy. With the development of bronchospasm, beta2-adrenomimetics is administered to the patient intravenously, with marked bradycardia, intravenous atropine is indicated. With the development of AV-blockade (II and III degrees) beta-adrenostimulants are injected intravenously. With the development of heart failure, the patient is administered cardiac glycosides and diuretics. When convulsions - intravenous diazepam.
Interaction with other drugs
With the simultaneous use of Binelol with nitroglycerin or antihypertensive drugs, the patient rapidly develops a sharp decrease in blood pressure, which can lead to collapse.
With the simultaneous use of this drug with general anesthesia in a patient, the risk of arterial hypotension significantly increases.
With the simultaneous use of Binelol with antidepressants or barbiturates, the hypotensive effect of beta-blockers increases, which should be considered when prescribing these pills.
This drug, like any other agent from the group of beta-blockers, cannot be canceled abruptly, as this can lead to the development of heart failure or myocardial infarction.
At the beginning of the course of therapy, the patient needs to daily monitor blood pressure and heart rate. In elderly patients, once every 4 months, it is necessary to check the condition of the organs of the urinary system and their function.
With the development of bradycardia, the drug can not be canceled, but simply reduce the daily dose.
If surgery is necessary, the patient should warn the surgeon that he is undergoing treatment with beta-blockers.
The drug with special care should be prescribed to patients with diabetes mellitus, since the active ingredient Binelol can affect the level of glucose in the blood.
Allergy sufferers may increase the risk of allergic reactions and bronchospasm.
If the patient is an active smoker and takes Binelol tablets, then he may experience a decrease in the therapeutic effect of the drug.
Conditions of storage and release of the drug
The drug is released in pharmacies by prescription. The storage time of tablets is 2 years from the date of manufacture. The drug should be kept out of the reach of children, avoiding direct sunlight at a temperature not higher than 25 degrees.
Analogs on the active substance (Nebivolol): Nebivator, Nebivolol, Nebilet, Nebilong, Nevotenz
Prices for Binafin tablets vary greatly in different pharmacies in Moscow. Price range - from 300 to 504 rubles