Binafin instructions for use
- Binafin instructions for use
- Release form and composition of the drug
- Pharmacological properties of the drug
- Indications for use
- Contraindications to use
- Dosage and administration
- Use of the drug during pregnancy and lactation
- Side effects and drug overdose
- Interaction with other drugs
- Conditions of release and storage of the drug
- Binafin analogues
- Binafin price
The drug Binafin belongs to the group of antifungal agents intended for the treatment of skin diseases. The international name of this drug is Terbinafine.
Release form and composition of the drug
The drug Binafin is available in tablet form with a dosage of 125 mg and 250 mg. The main active ingredient of the drug is terbinafine hydrochloride, as well as additional auxiliary components.
Pharmacological properties of the drug
This drug belongs to the group of antifungal drugs and has a high therapeutic activity against infections caused by fungi. The active ingredient of the drug has a negative effect on the cells of the fungus, inhibiting their metabolic processes and vital processes, thereby causing their death.
The active ingredient of the drug is highly effective against many varieties of fungi that cause various diseases of the hair, skin and nail plate.
When taking the drug inside the main active substance for 2 hours is absorbed into the general bloodstream and deposited on the tissues of the skin, nails, hair structures. The maximum concentration of the drug is observed precisely in the areas of damage, thereby causing the destruction of fungal cells. The active substance penetrates the nail plate only a week after the start of the drug.
Indications for use
Binafin tablets prescribed to patients with the following conditions:
- Treatment of diseases of the skin of fungal origin (ringworm);
- Fungal diseases of the scalp;
- Fungal lesions of the nail plate, provoked by dermatophytes (onychomycosis);
- Generalized skin lesions caused by Candida fungi.
Contraindications to use
The main contraindication to the use of Binafine tablets is an individual intolerance to the components of the drug or past allergic reactions in a patient.
The study of the effect of active ingredients on liver function in patients with liver failure has not been conducted, therefore, one should be very careful or not to prescribe Binafin to such patients.
Dosage and administration
The dosage of the drug and the duration of the course of therapy are determined by the doctor, depending on the diagnosis of the patient, the severity of the clinical symptoms, age, body weight and many other factors. According to the instructions for the preparation of tablets recommended to take 1 per day. If necessary, a single use in order to prevent the dose is calculated depending on the patient's body weight.
The drug can be used in pediatric practice for the treatment of fungal skin diseases in children older than 2 years. The dosage for children is as follows: with a child’s body weight from 20 to 40 kg, the daily dose of the drug is no more than 125 mg, for children weighing more than 40 kg, the recommended daily dose is 250 mg. If the child weighs less than 20 kg, then the drug is shown in the amount of 62 mg per day, that is, half the tablet with a dosage of 125 mg.
The duration of treatment depends largely on the severity of the pathological process. According to the instructions for the preparation, tablets for fungal skin diseases are prescribed for a period of at least 2 weeks. If necessary, the course of therapy can be continued up to 1.5 months. Constantly monitoring the effectiveness of treatment by a doctor. For fungal lesions of the scalp and hair, the duration of therapy is at least 1 month. For fungal diseases of the nail plate, the minimum course of treatment is 1 month, the maximum - 3 months.
Patients with chronic liver or renal failure require dose adjustment.
Use of the drug during pregnancy and lactation
In medicine, there is no reliable data on the safety of Binafine tablets in the first trimester of pregnancy, so the drug is not prescribed for the treatment of expectant mothers at this time. In the 2 and 3 trimesters of pregnancy, the indications for using this drug are very limited. Expectant mothers can drink these pills only when the expected benefit is higher than the potential risk to the fetus.
Binafin tablets during breastfeeding is prescribed to women only if she agrees to stop feeding and transfer the baby to the formula. This is due to the ability of the main active ingredient of the drug to penetrate into breast milk, and then into the body of a child with food.
Side effects and drug overdose
In most cases, tablets of this drug are well tolerated by patients. Side effects occur only in rare cases and are mild. The most common side effects are as follows:
- Disturbed appetite;
- Change stool (diarrhea);
- Stomach ache.
In rare cases, allergic rashes on the skin, itching and flushing of the skin are observed.
If these symptoms appear, treatment with the drug should be stopped and consult a doctor.
An overdose of the drug occurs in rare cases and is accompanied by allergic rashes on the skin, diarrhea and headaches. In these cases, the patient is canceled a course of therapy and enterosorbents are prescribed. Very rarely, patients require gastric lavage.
Interaction with other drugs
With the simultaneous use of Binafina tablets with combined oral contraceptives significantly reduces the effect of the latter, as the doctor must necessarily warn women.
With the simultaneous use of this drug with drugs from the group of beta-blockers may be a decrease in their therapeutic effect. If necessary, treatment with beta-blockers should observe certain intervals between taking the medication.
Conditions of release and storage of the drug
The tablets are available in pharmacies without a prescription. The shelf life of the drug is 3 years from the date of manufacture indicated on the package. Tablets should be kept out of reach of children at a temperature not exceeding 25 degrees.
Analogs on the active substance (Terbinafin): Atifin, Binafin, Lamisil, Lamitele, Terbizil, Terbinafin, Terbinox, Terbifin, Termikon, Ungusan, Fungerbin, Exiter, Exifin
Prices for Binafin tablets vary greatly in different pharmacies in Moscow. Price range - from 450 to 700 rubles.