Bifidumbacterin dry instruction for use
Bifidumbacterin (Bifidobacterium bifidum) refers to the means that normalize the intestinal microflora, and is used to treat pathologies caused by pathogenic bacteria.
Form of issue and composition
Bifidumbacterin dry is released as a lyophilized dried microbial mass of live bifidobacteria, sealed in glass bottles of 5 doses in a cardboard box of 10 pieces. The crystalline or porous microbial mass can be light gray, beige, dark brown or marbled. Has a specific, fuzzy smell. After dissolving the contents of the ampoule, an opaque suspension forms.
For the stability of the dosage form, live bifidobacteria are lyophilized in a sucrose-gelatin-lactic medium. The environment where bacteria are cultivated consists of yeast autolysate, food agar, lactose monohydrate, sodium chloride, enzymatic hydrolyzate casein, L-cystine, purified water.
Mechanism of action
Bifidumbacterin, due to its antagonistic properties against pathogens (staphylococcus, shigella, protea, enteropathogenic E. coli, yeast-like fungi) normalizes the intestinal microflora. This allows us to normalize the digestive and protective function of the intestine, optimize metabolic processes, increase the nonspecific resistance of the organism to infections. Bifidobacteria are involved in the synthesis of important B vitamins, as well as digestive enzymes.
Indications for use
- dysbiosis after treatment with antibiotics, hormonal drugs, as well as radiation therapy;
- treatment of acute and chronic intestinal infections (dysentery, viral diarrhea, salmonellosis, escherichiosis);
- diarrhea caused by a stressful situation, unusual food, extreme conditions;
- purulent-infectious diseases in children (sepsis, pneumonia);
- allergic reactions, including diathesis in children;
- dysfunction of the intestine in newborns;
- chronic and acute inflammatory bowel diseases (colitis, enterocolitis).
Bifidumbacterin can be used alone or in combination with other medicines.
Bifidumbacterin can not be used if there is an increased sensitivity to the components of the drug.
Dosing and Administration
Bifidumbacterin is used inside. Before use, the bottle is opened and dissolved with boiled water at room temperature at a rate of 1 teaspoon (5 ml) per 1 dose of the substance. Since the vial contains 5 doses, 5 ml of water is added to the vial first, and then the solution is transferred to a beaker and is topped up with 20 ml (4 teaspoons) of water.
The prepared solution is drunk 20-30 minutes before meals. Breast children can be given the drug just before they are fed. Dissolved Bifidumbacterin is not subject to storage.
Newborn Bifidumbacterin is recommended to give 1-2 doses 3 times a day, starting from the first day of discharge from the maternity hospital.
Children under 6 months of the drug give 3 doses 3 times a day.
From 6 to 12 months, Bifidumbacterin children are prescribed 5 doses 2 times a day.
Children from 1 year and adults take the drug 5 doses 3 times a day.
The course of treatment is determined by the severity of the disease and can range from one week to three months.
There are practically no side effects of Bifidumbacterin. At the beginning of treatment there may be a temporary relaxation of the stool.
Probifor, Bifiform, Bifikol.
Terms and conditions of storage
Bifidumbacterin is stored in the original packaging in the refrigerator at a temperature of 2 to 8 0 C. Shelf life - 1 year.
Bifidumbacterin dry price
Bifidumbacterin dry powder lyophilized, 5 doses in glass bottles - 80-90 rub.