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Betaxolol instructions for use

Betaxolol instructions for use

Betaxolol eye drops is a drug used in the treatment of glaucoma.

Release form and composition

The drug is produced in the form of eye drops, with a drug concentration of 0.5%. The main active ingredient is betaxolol, belonging to the cardio-selective group - beta -1-adrenergic blockers.

pharmachologic effect

The drug has antiglaucoma, antianginal, hypotensive and antiarrhythmic effects. Antianginal effect is manifested in a decrease in myocardial oxygen demand. The effect of the drug appears 2-3 hours after administration, the maximum is reached after 3-4 hours, the duration of the effect is 12-24 hours. From the body is excreted in the urine.

Indications for use

Betaxolol (eye drops) is used in ophthalmology for local use in the following diseases:

  • chronic open-angle glaucoma;
  • condition after laser trabeculoplasty;
  • increased intraocular pressure.

Dosing regimen

For adults, it is recommended to dig in 1 drop in the affected eye with a 0.5% solution 2 times a day.

To normalize the indices of intraocular pressure, you will need to use Betaxolol for several weeks, so the evaluation of the effectiveness of the drug is carried out after 4 weeks.


Drug interactions

The effectiveness of Betaxolol decreases when taken together with adrenomimetics.

Co-administration with antidiarrheal drugs and antacids leads to a decrease in the absorption of the active substance of the drug.

Simultaneous use with other antihypertensive drugs enhance the antihypertensive effect of Betaxolol.

The use of halogen-containing agents in inhalation anesthesia increases the negative inotropic effect.

Estrogens, glucocorticoids, NSAIDs, the hypotensive effect of the drug is weakened.

Cardiac glycosides can enhance bradycardia.

The use of antidepressants lowers blood pressure and leads to the risk of hypotension.

Diltiazem, amiodarone, verapamil and quinidine drugs increase the possibility of conduction disorders, contractility and heart automatism.

The combined use of lidocaine increases its concentration in the blood.

The simultaneous use of sulfasalazine increases the amount of betaxolol in the blood.

Contraindications

Sinus bradycardia, cardiogenic shock, sinoatrial blockade, severe chronic heart failure, significant impairment of peripheral circulation, AV block 2 and 3 degrees, sick sinus syndrome, individual intolerance to the components of the drug.

Side effects

On the part of the digestive system are rarely nausea, vomiting, abdominal pain.

On the part of the cardiovascular system at the early stage of treatment, AV-blockade, arterial hypotension, sinus bradycardia, Raynaud's syndrome , heart failure are possible.

On the part of the respiratory system: bronchospasm.

On the part of the nervous system: sleep disturbance, drowsiness, depression, dizziness, limb perestesiya, asthenia.

Local reactions: immediately after instillation, occasional discomfort in the eyes, lacrimation; decreased corneal sensitivity, itching, erythema, keratitis, photophobia, anisocoria, staining of the cornea in the form of spots.

Allergic reactions: skin manifestations similar to psoriasis .


Pregnancy and lactation

During pregnancy and breastfeeding, taking Betaxolol is permitted only in situations where the potential benefit to the patient is significantly higher than the perceived risk to the baby or fetus.

special instructions

It is not advisable to use in chronic bronchitis, bronchial asthma. Caution should be taken with diabetes, thyrotoxicosis, bronchial hyperactivity.

In the presence of renal failure, it is possible not to adjust the dosage, but at the early stage of treatment, constant clinical observation is necessary.

At the beginning of treatment, symptoms of heart failure may appear in predisposed patients.

Cancel the drug should be gradually, especially in the presence of angina and ischemic heart disease.

In case of angle-closure glaucoma, Betaxolol should be used together with miotikami, since the drug does not affect the size of the pupil. After treatment with other antiglaucoma drugs, they are gradually discontinued (1 week per drug) and only then transferred to Betaxolol.

Conducting a planned surgery requires the abolition of the drug

During the application of Betaxolol in the form of eye drops, contact lenses should not be worn.

In pediatric practice, Betaxolol is not recommended.

Care should be taken in applying to persons whose activities require quick reactions and high attention.

Overdose

When using the drug in a dose above the therapeutic norm, the following symptoms may appear: hypotension, arrhythmia, bradycardia, acute heart failure, hypoglycemia, bronchospasm, convulsions , collapse.

The treatment is carried out with the help of gastric lavage and the appointment of adsorbing substances.

Pharmacy holidays

The drug is released from pharmacies only by prescription.

Storage

The drug Betaxolol refers to List B, which must be stored at a temperature of 30 grams C, in a dry place.

Betaxolol analogues

Analogs on the active substance: Betalmik EU, Betoptik, Betoftan, Ksonef, Lokren.

Betaxolol price

Betaxolol eye drops 0.5% 5ml - from 98 rubles.

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