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Betadine solution instructions for use

Betadine solution instructions for use

Betadine solution refers to a broad-spectrum drugs and is used as an antiseptic for local and external use.

Release form and composition

The drug Betadine released in the form of a 10% dark brown solution with a volume of 30 ml, 120 ml and 1000 ml. The drug should not contain precipitated or suspended particles.

1 ml of the solution contains as active substance 100 mg of povidone-iodine.

Glycerol, citric acid, nonoxyl 9, sodium hydroxide pp 10%, disodium hydrogen phosphate, purified water are used as excipients.

pharmachologic effect

Disinfectant and antiseptic properties of the drug is manifested due to iodine, which is released from the complex with polyvinylpyrrolidone when interacting with the skin and mucous membranes. As a result, iodine binds to the proteins of bacteria cells and leads to the death of microorganisms. It has a high bactericidal effect on gram-negative and gram-positive bacteria. It also has a devastating effect on viruses, fungi, spores and protozoa.


Prolonged use of the drug Betadine in large areas of the skin with extensive wounds and burns, leads to the absorption of large amounts of iodine. The increased content of iodine in the blood passes 7-14 days after the last dose of the drug. In people with a healthy thyroid gland, such an increase in iodine does not affect the hormones. From the body iodine excreted only by the kidneys.


Iodine that reacts with proteins of microorganisms loses its color. Accordingly, an indicator of the effectiveness of the drug is the intensity of brown staining. After the disappearance of color, you can re-apply the drug. Betadine solution is easily washed off and dissolved in water.

Indications for use

  • treatment of viral, fungal and bacterial infections of the skin, prevention of superinfection with dermatological diseases;
  • prevention and treatment of wound infections in traumatology, surgery, dentistry, combustiology;
  • disinfection of mucous membranes and skin before invasive studies (biopsy, puncture, injection) and before surgical operations;
  • treatment of trophic ulcers, bedsores, diabetic foot;
  • disinfection of the skin around the catheters, drains, probes;
  • antiseptic treatment of the oral cavity during dental operations;
  • disinfection of the birth canal during simple gynecological operations (introduction of the intrauterine device, artificial termination of pregnancy), a polyp, erosion coagulation;
  • Betadine diluted solution is used in the prevention of ophthalmia in newborns.

Mode of application

Betadine solution is used undiluted and diluted for external application to the skin. The drug should not be diluted with hot water. Not prolonged heating of the solution and temperature of 36-37 ° C is allowed. During the preoperative treatment, care must be taken to ensure that no excess solution remains under the patient, which can lead to skin irritation.


When treating burns and wounds, skin and hands before surgery, catheterization of the bladder, before punctures and injections, an undiluted Betadine solution is used.

Allowed to use Betadine solution several times a day.

Observe the following rules when handling hands:

Hygienic disinfection of hands: 3 ml of undiluted solution 2 times - each portion of the liquid should remain on the skin of the hands for 30 seconds.

Surgical disinfection of hands: 5 ml of undiluted solution 2 times - each portion of the liquid should be in contact with the skin for 5 minutes.

For the full effect of disinfecting the skin, the applied solution is left to dry.

For the above indications, Betadine solution diluted with tap water is used. In surgical procedures, when treating wounds and burns for breeding, isotonic sodium chloride solution or Ringer's solution is used. The diluted solution is prepared immediately before use.


  • individual intolerance to the components of the drug;
  • pregnancy and lactation;
  • adenoma or dysfunction of the thyroid gland;
  • hyperthyroidism;
  • renal failure;
  • Herpetiformis dermatitis Dühring;
  • children up to 1 year.

Side effects

In case of hypersensitivity to the components of the drug, an allergic reaction is possible in the form of edema, itching, burning or redness. Such manifestations require discontinuation of the drug.

With prolonged use of the drug in predisposed persons hyperthyroidism may occur.

Intensive application of the solution to large areas with burns can lead to electrolyte imbalance, serum osmolarity, metabolic acidosis, and renal dysfunction.

In rare cases, acute generalized reactions are possible, accompanied by suffocation or hypotension.

Application features

Use of the drug during pregnancy or lactation is allowed only on condition of absolute indications and in small doses.

Newborns and children up to 6 months are allowed to use Betadine solution only with strict indications. In the future, it is necessary to monitor the activity of the thyroid gland.


With excessive use of the drug, the following symptoms of intoxication are possible: taste of metal in the mouth, increased salivation, pain in the mouth and throat, eye irritation, heartburn, skin reactions, gastrointestinal disturbances, anuria, pulmonary edema.

The treatment is carried out by the immediate introduction of foods containing protein or starch (starch solution in milk or water). The stomach is washed with sodium thiosulfate solution or injected intravenously. It is necessary to carefully monitor the activity of the thyroid gland for the early detection or elimination of hyperthyroidism.

Drug interactions

The drug is not compatible with other antiseptics containing enzymes, alkalis and mercury.

Storage conditions

The drug should be stored in a dry, dark, cool and out of reach of children.

Analogs of Betadine Solution

Analogs on the active substance: Akvazan, Braunodin B. Brown, Povidone-iodine

Betadine solution Price

Betadine solution 10% 30 ml - from 170 rubles.

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