Beloderm instructions for use
Beloderm is a drug of the glucocorticosteroid group intended for the treatment of various inflammatory processes of the skin.
Release form and composition
Beloderm is produced in the form of ointment and cream, in aluminum tubes of 15 g and 30 g each. The tube is placed in cardboard packaging with instructions.
Beloderm ointment for external use of 0.05%
The main active ingredient is betamethasone dipropionate. 1 g of ointment contains 640 mcg betamethasone dipropionate, which corresponds to 500 mcg betamethasone.
Auxiliary components: Vaseline, mineral oil.
Beloderm cream for external use 0.05%
The main active ingredient is betamethasone dipropionate. 1 g of cream contains 640 mcg betamethasone dipropionate, which corresponds to 500 mcg betamethasone.
Excipients: sodium dihydrogen phosphate monohydrate, chlorocresol, mineral oil, petrolatum, phosphoric acid, macrogol cetostearate, cetostearyl alcohol, sodium hydroxide, water.
Pharmacodynamics. Betamethasone belongs to the group of synthetic glucocorticosteroids. It has anti-inflammatory and anti-allergic, antipruritic and immunosuppressive effects. It also has vasoconstrictor, antiexudative and antiprofilerative properties.
When applied to the skin, betamethasone inhibits the production and release of histamine, prostaglandins and lysosomal enzymes - substances involved in the development of inflammatory and allergic reactions. Also, the active ingredient slows the development of edema.
When applied to the skin, the drug has a rapid local effect in the focus of inflammation, reducing erythema, swelling, itching and irritation, pain.
Pharmacokinetics. Betamethasone absorption into the blood varies depending on the general condition of the skin, the presence of mechanical damage and inflammatory processes (when applied to damaged and inflamed skin, the product is absorbed faster). Systemic absorption after topical administration is 12–14%. About 64% of betamethasone binds to plasma proteins. The metabolism of the active substance occurs in the liver. Betamethasone is excreted mainly with bile, in small quantities (up to 5%) - with urine.
Indications for use
Beloderm is prescribed for various skin pathologies requiring anti-inflammatory therapy with topical glucocorticosteroids. It:
- allergic contact dermatitis;
- contact dermatitis, including professional;
- non-allergic dermatitis, including solar, radiation;
- atopic dermatitis ;
- bullous dermatosis;
- neurodermatitis ;
- various forms of eczema;
- psoriasis ;
- exudative erythema multiforme;
- lichen planus ;
- discoid lupus erythematosus;
- reaction to insect bites;
- pruritus of various nature.
Beladerm does not apply to:
- infectious skin inflammations of a bacterial, viral or fungal nature;
- open wounds;
- trophic ulcers;
- varicose veins;
- acne vulgaris;
- perioral dermatitis;
- chicken pox;
- skin tuberculosis;
- skin manifestations of syphilis;
- skin reactions to vaccine administration;
- cancer of the skin and subcutaneous structures;
- individual intolerance or hypersensitivity to betamethasone or any auxiliary component;
- children under 6 months.
Beloderm should not be applied to the skin in the eye area, since betamethasone on the eyeball mucosa may trigger the development of glaucoma, cataracts, fungal infections or exacerbation of herpes.
Dosing and Administration
Both cream and ointment are applied externally. The tool is applied in a thin layer on dry clean skin, lightly rubbed. Frequency of use - twice a day. On areas with hardened and denser skin (on the feet, knees, elbows) or in places where the product is quickly erased, Beloderm can be applied more often. The full therapeutic course should not exceed 4 weeks. Repeated treatment courses are possible throughout the year.
In the treatment of chronic diseases to prevent relapse, ointment should be applied for some time after the symptoms disappear.
Occlusive dressings are used only as prescribed by a physician, since their use enhances both the therapeutic effect of the cream and its toxic effect on the body.
Beloderm cream is used to treat acute inflammatory processes in the skin (including weeping).
Beloderm ointment is recommended for the treatment of subacute and chronic dermatoses, including dry and scaly lesions. Also means is applied if necessary occlusal action.
In some situations, the use of Beloderma can cause the development of undesirable side effects:
- hypersensitivity reactions - burning, itching, redness of the skin;
- acne-like changes;
- skin atrophy (due to collagen reduction);
- stretch marks (stretch marks);
- hyperpigmentation / hypopigmentation;
- hypertrichosis (excessive hair growth);
- telangiectasia (dilation of small vessels of the skin, manifested by vascular networks or asterisks);
- decrease in functions of sweat glands;
- secondary skin infections.
The resulting side effects are often mild. The reason for their appearance is considered to be suppression or insufficiency of the function of the adrenal cortex. The provoking factors include:
- long-term use of Beloderma (longer than 3 weeks);
- treatment of large areas of skin;
- the use of large doses of funds;
- application of the product to the skin with mechanical damage (scratches, abrasions);
- use of the drug under the occlusive dressing;
- use of funds in childhood.
At occurrence of side effects it is necessary to cancel the use of Beloderma and conduct symptomatic treatment.
Symptoms of systemic overdose are metabolic glucose, headaches. If there are signs of overdose, the drug should be discontinued, restoration of water-salt balance, symptomatic therapy.
During treatment with Beloderm, it is important to take into account the following points:
- you can not use the treatment for the skin of the face for longer than 7 days, as side effects may develop - perioral dermatitis, acne , rosacea;
- Treatment of the skin in the folds (inguinal folds, armpits) should be short-lived (natural occlusion occurs, resulting in an increased risk of stretch marks);
- when attaching a secondary bacterial or fungal infection, additional prescription of local antibiotics and antifungal drugs is required;
- in case of liver failure, you can apply small doses of the cream without using a bandage, use the tool in short courses;
- Beloderm does not affect the ability to concentrate attention, drive vehicles and other mechanisms;
- use of the drug Beloderm during pregnancy is possible only in situations where the expected benefit to the mother outweighs the potential risks to the fetus;
- it is possible to use the drug during lactation, but only under strict indications (it is not possible to apply an ointment on the skin of the mammary gland immediately before feeding);
- Beloderm can be used to treat children older than 6 months, but with caution and the lowest possible course (in children there is a greater absorption of the drug due to the larger ratio of skin surface area to body weight, resulting in increased toxicity);
- it is impossible to apply the remedy for the bandages and diapers for children, since the absorption of the drug increases and the risk of side effects increases.
Similar preparations with the same active ingredient include: Akriderm cream, Betliben cream, Celestoderm-B cream.
Terms and conditions of storage
The drug is stored at a temperature of 15 ° C to 25 ° C, protected from sunlight and moisture, inaccessible to children. Do not freeze. The shelf life of the cream and ointment Beloderm is 4 years. Do not use the tool after the expiration date indicated on the package.
The price of Beloderm ointment and Beloderm cream
Beloderm ointment for external use 0.05%, tube 15 g - from 127 rubles.
Beloderm cream for external use 0.05%, tube 15 g - from 127 rubles.