Atrovent inhalation solution
Solution for inhalation Atrovent is a drug that has proven itself in the treatment of bronchial asthma, both acute its conditions, and with maintenance therapy. Dosages of this drug and the course of treatment is established only by the attending physician.
Form of issue and composition
The drug Atrovent is released in the form of a solution for inhalation. The active substance, which is responsible for the pharmacological properties, is represented by ipratropium bromide monohydrate in an amount of 261 μg per 1 ml of solution, which is approximately equal to 250 μg of ipratropium bromide anhydrous. In addition, Atorent includes disodium edetate, benzalkonium chloride, purified water, sodium chloride and hydrochloric acid.
The inhalation solution is a colorless liquid, without additional inclusions.
This preparation is produced in amber bottles in volume of 20 ml, with a screw cap. They are supplied with instructions and packed in a cardboard box.
Indications for use
Atrovent is prescribed for chronic obstructive pulmonary disease, which causes bronchospasm (including chronic obstructive bronchitis, as well as pulmonary emphysema), with mild or moderate bronchial asthma. In these cases, the inhaler plays the role of maintenance therapy.
In acute attacks of bronchospasm, Atrovent is combined with inhaled beta2-agonists.
A solution for inhalation is not recommended for persons with closed-angle glaucoma and pregnant women in the first trimester.
Do not apply Atrovent if the patient has allergies to atropine, ipratropium bromide and their derivatives, as well as to other components of the drug.
Dosing and Administration
In each specific situation, the doctor selects the dosing regimen individually, proceeding from the fact that 1 drop of the drug contains 0.0125 mg of anhydrous ipratropium bromide, and 1 ml is 20 drops.
Do not exceed the prescribed daily dose. During the course of treatment the patient should be observed by a doctor.
In the absence of improvements or deterioration of the patient's health, an urgent consultation with the attending physician is required, which will suggest new methods of treatment. If there is shortness of breath or difficulty in breathing, you should consult a specialist.
According to the dosage instructions the following:
- With maintenance therapy
- adults 2 ml (which is 0.5 mg of active ingredient) 3-4 times a day; the maximum daily dose of 8 ml (or 2 mg);
- children from 6 to 12 years of 1 ml (0.25 mg); the maximum daily dose of 8 ml;
- children under 6 years of age 0.4 - 1 ml; the maximum dose of 4 ml.
The treatment of children is conducted under medical supervision.
- In acute bronchospasm
- adults and children over 12 years of 2 ml once, but can be prescribed repeated inhalation, until the condition does not stabilize. How often procedures are performed, the doctor recommends. Sometimes complex treatment with inhaled beta2-adrenomimetics is prescribed;
- children 6-12 years of age per 1 ml. Recommendations are the same as in adult patients.
- children under 6 years of 0.4-1 ml. The recommendations are the same.
The prescribed dose of the solution for inhalation Atrovent is diluted in 0.9% sodium chloride solution to 3-4 ml and inhaled with a nebulizer. Do not use the prepared solution again.
The dosage regimen will depend on the type of nebulizer, as well as the inhalation method. By spending the amount of diluted drug, you can control the duration of the inhalation.
If a centralized oxygen system is used, the flow rate should be 6-8 liters per minute.
Among the side effects of the drug can be isolated irritation, which appears in connection with the features of the application. Most often, patients receiving inhalation with Atrovent complained of coughing, headache, dry mouth, constipation or diarrhea, throat irritation, dizziness, or nausea.
If you try to distribute the side effects into groups, you get the following:
- Pathologies of the immune system:
- anaphylactic shock;
Urticaria , itching;
- Pathologies of the nervous system:
- Pathology of the organs of vision:
- clouding and visual impairment;
Pain and pain in the eyes;
Reddening of the conjunctiva;
- Pathology of the cardiovascular system:
- atrial fibrillation;
- palpitations and increased heart rate;
Supraventricular tachycardia .
- Pathology of the respiratory system:
- irritation and dryness of pharynx;
Swelling of the pharynx;
- Pathologies of the gastrointestinal tract:
- dry mouth;
- edema of the mouth.
- Kidney pathology:
- worsening of urinary retention.
At treatment in any case it is impossible to exceed recommended daily doses, even for a cupping of acute conditions.
With due care, Atrovent is prescribed for obstruction of the urinary tract and benign prostatic hyperplasia.
Disodium edetate and benzalkonium chloride, which are part of the solution, can lead to a narrowing of the lumen of the bronchi.
Patients suffering from cystic fibrosis may develop a slowing down of the peristalsis of the gastrointestinal tract.
If you get a solution for inhalation in the eyes, there may be a halo or colored spots, discomfort and pain in the eye, visual impairment, and reddening of the conjunctiva. In this situation, after examining the ophthalmologist, vasoconstricting drops are prescribed.
The drug is used with a nebulizer with a special tip for the mouth, or a mask matched to the size.
When administering the Atrovent inhalation solution, pregnant women are weighed against all possible risks to the child and the benefits of using the medication for the mother.
During the period of breastfeeding the drug is prescribed with caution, despite the fact that there is no data on the ingestion of active ingredient Atrovent into breast milk.
Care must be taken by patients engaged in driving a car, as well as other activities requiring increased attention.
To Atorvent analogues having the same active substance are:
- Atrovet N;
- Ipratropium bromide monohydrate;
- Ipratropium Steri-Neb.
Among drugs with a similar indication for use, primarily in the treatment of bronchial asthma, there are:
- Seredid Multidisk;
- Symbicort Turbuhaler;
- Solutan et al.
Terms and conditions of storage
Atrovent should be stored in a place inaccessible to children, at a temperature of less than +30 ° C. Do not freeze the solution.
Shelf life is 3 years from the date of manufacture. At the end of this period, the drug should not be used.
Vacation from pharmacies
The described solution for inhalations is released by prescription.
Atrovent solution for inhalations, vial-dropper 20 ml. - from 225 rubles.