The Argosulfan Ointment: instruction manual, price, reviews, analogs of Argosulfan cream
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Argosulfan user's guide

Argosulfan user's guide

Argosulfan is an antiseptic and disinfectant in the form of a cream that is used to accelerate the healing of wounds, treat and prevent their infection, reduce pain, and prepare a wound for skin transplantation.

The composition of Argosulfan includes a silver salt of sulfatiazole - an antibiotic with a wide spectrum of action from the group of sulfonamides. It actively blocks the growth and multiplication of bacteria in burns, trophic, purulent and other skin lesions, and silver ions enhance the antibacterial action of sulfatiazole and reduce its allergic properties.

Due to its dosage form, the preparation perfectly moistens the wound surface, reduces burning, significantly facilitates epithelization and accelerates the complete restoration of tissues.

A significant advantage of the drug over other antiseptic and antibacterial agents is the possibility of the drug in young children (from 2 months), since children are often very mobile and prone to receiving various abrasions and burns.

Form of issue

Medicinal form of Argosulfan - cream in a tube with a volume of 15 and 40 g. It is a white mass, soft to the touch, with a pink or light gray tinge and a uniform consistency.


In 1 gram of the medicinal product contains:

  • sulfatiazole - 20 mg;
  • the basis of the cream (paraffin, petroleum jelly, glycerin, and other auxiliary substances) - up to 1 g.

Indications for use

Argosulfan is used to prevent infection and:

  • for the treatment of burns of different severity in the defeat of tissues with high temperature (thermal burns), solar or X-rays, exposure to electricity, etc .;
  • for the treatment of frostbites and their consequences, resulting from low ambient temperatures or by contact;
  • prevention of complications in bedsores, trophic ulcers that have arisen due to a decrease in the supply of tissues due to stagnation of blood in chronic venous insufficiency, damage and occlusion of vessels with obliterating endarteritis, sclerosing arterioles and capillaries in diabetes mellitus, etc .;
  • for treatment of purulent lesions of the skin and mucous membranes, prevention of wound suppuration with minor cuts and abrasions;
  • in dermatological practice for the treatment of infected skin inflammations, with contact dermatitis complicated by pustular eruptions, bacterial eczema, streptodermia, staphyloderma.


The drug is contraindicated:

  • when hypersensitivity reactions to the active ingredients or excipients included in the composition of the drug;
  • with deficiency of glucose dehydrogenase enzyme;
  • babies up to 2 months and premature babies because of the risk of developing jaundice.

Application in pregnancy is not recommended. When breastfeeding the drug can be prescribed only by a doctor with small wound surfaces and a significant benefit for the mother, exceeding the risk of negative consequences for the baby.

Dosing and Administration

You can apply Argosulfan simply externally or use under a bandage.

The drug is applied with a sterile gauze swab completely to the entire damaged surface, which must be cleaned and processed beforehand. Application is done by a thin layer 2-3 times a day. If during the day some part of the wound is left without cream, you need to add it additionally.

Before applying the drug to the infected surface, it is recommended to wash it with an antiseptic, for example, chlorhexidine solution.

Treatment is performed until the wound is fully healed or before the skin is transplanted, but not more than 2 months.

Side effects

Of the side effects can be observed only skin-allergic reactions. There is rarely a burning sensation or redness in the place of application of the cream.

With prolonged use of the drug, a change in the blood picture is possible due to the systemic effect of sulfonamide, as well as the development of desquamative erythroderma.

special instructions

  • it is necessary to monitor blood indices for long-term use, extensive wound surface and in persons suffering from hepatic or renal insufficiency;
  • when using the cream in patients with extensive burn lesions of the skin, in a state of shock, it is necessary to observe precautions because of the possible development of allergic reactions;
  • the cream does not cause darkening of the skin or clothing fabric;
  • does not affect the central nervous system (can be used for work that requires increased attention and concentration).

Terms and conditions of storage

Shelf life is 2 years. After the expiration of this period, the use of the medicinal product is prohibited. Keep the tablets in a place inaccessible to children, with a temperature range not exceeding 25 degrees. You can not freeze!

Argosulfan analogues

There are no complete analogues of Argosulfan on the basis of the silver salt of sulfatiazole. Other creams, liniments or sulfonamide-containing ointments with a similar effect are represented by such preparations:

  • Argedin (manufacturer Bosnalijek, Bosnia and Herzegovina), Dermazin (Lek, Slovenia) and Sulfargin (Tallinn Pharmaceutical Plant, Estonia) are a cream whose active ingredient is sulfadiazine silver salt. They are produced in a tube of 40, 50 grams, as well as in a 250-gram can. They are used for the same indications as Argosulfan. In addition, this sulfonamide is active against fungi of the genus Candida and dermatophytes, which can be prescribed for candidiasis and other skin mycoses;
  • Mafenide acetate ointment 10% is available in packing 50 g in a jar. The drug also has an antifungal effect against Candida;
  • Streptocide ointment and liniment 5% and 10% are produced in a can of 25 and 50 g. Indications for use are similar to Argosulfan.

The price of Argosulfan cream

Argosulphan cream for external use 2%, tube 15 g - from 278 rub.

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