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Argosulfan instructions for use

Argosulfan instructions for use

Argosulfan is an antiseptic and disinfecting drug in the form of a cream that is used to accelerate wound healing, treat and prevent their infection, reduce pain, and prepare wounds for skin grafts.

The composition of Argosulfan includes the silver salt of sulfathiazole - an antibiotic with a broad spectrum of action from the group of sulfonamides. It actively blocks the growth and reproduction of bacteria in case of burns, trophic, purulent and other skin lesions, and silver ions enhance the antibacterial effect of sulfathiazole and reduce its allergic properties.

Due to its dosage form, the drug perfectly moisturizes the wound surface, reduces burning, significantly facilitates epithelization and accelerates the full recovery of tissues.

A significant advantage of the drug over other antiseptic and antibacterial agents is the possibility of the drug in young children (from 2 months), since children are often very mobile and prone to getting various abrasions and burns.

Release form

Dosage form Argosulfan - cream in a tube with a volume of 15 and 40 g. It is a white mass, soft to the touch, with a pink or light gray tint and a uniform consistency.


1 gram of the drug contains:

  • sulfathiazole - 20 mg;
  • cream bases (paraffin, vaseline, glycerin, and other excipients) - up to 1 g.

Indications for use

Argosulfan is used to prevent infection and:

  • for the treatment of burns of varying severity with the defeat of tissue with high temperature (thermal burns), sun or X-rays, exposure to electricity, etc .;
  • for the treatment of frostbite and their effects resulting from low ambient temperature or by contact;
  • prevention of complications of pressure sores, trophic ulcers, arising from the reduction of tissue nutrition due to blood stagnation in chronic venous insufficiency, vascular lesion and occlusion during obliterating endarteritis, hardening of arterioles and capillaries in diabetes mellitus, etc .;
  • for the treatment of purulent lesions of the skin and mucous membranes, prevention of wound suppuration with small cuts and abrasions;
  • in dermatological practice for the treatment of infected inflammation of the skin, with contact dermatitis, complicated by pustular rash, bacterial eczema, streptoderma, staphylodermia.


The drug is contraindicated:

  • in case of hypersensitivity reactions to the active or auxiliary substances included in the composition of the medicinal product;
  • with deficiency of the enzyme glucose dehydrogenase;
  • babies up to 2 months and premature babies because of the risk of jaundice.

Use during pregnancy is not recommended. When breastfeeding the drug can be prescribed only by a doctor with small wound surfaces and significant benefits to the mother, exceeding the risk of negative consequences for the baby.

Dosing and Administration

Argosulfan can be applied externally or used under the bandage.

The drug is applied with a sterile gauze pad completely on the entire damaged surface, which must be pre-cleaned and processed. Application is made with a thin layer 2-3 times a day. If during the day some part of the wound is left without cream, you need to add it additionally.

Before using the drug on the infected surface, it is recommended to wash it with an antiseptic, for example, chlorhexidine solution.

The treatment is carried out until the wound is completely healed or before the skin grafting, but not more than 2 months.

Side effects

Of the side effects, only skin-allergic reactions can be observed. Rarely there is a burning sensation or redness at the site of application of the cream.

With prolonged use of the drug may change in the blood picture due to the systemic action of sulfanilamide, as well as the development of desquamative erythroderma.

special instructions

  • it is necessary to monitor blood counts with long-term use, extensive wound surface and in persons suffering from hepatic or renal failure;
  • when using the cream in patients with extensive burn skin lesions in a state of shock, it is necessary to observe precautions because of the possible development of allergic reactions;
  • cream does not cause darkening of the skin or fabric of clothing;
  • does not affect the central nervous system (it can be used when performing work that requires increased attention and concentration).

Terms and conditions of storage

Shelf life is 2 years. After the expiration of this period, the use of the drug is prohibited. Keep the tablets should be out of the reach of children, at a temperature range not exceeding 25 degrees. You can not freeze!

Analogs of Argosulfan

Full analogues of Argosulfan based on the silver salt of sulfathiazole does not exist. Other creams, liniments or ointments of sulfanilamide composition with a similar effect are represented by such preparations:

  • Argudene (manufacturer Bosnalijek, Bosnia and Herzegovina), Dermazin (Lek, Slovenia) and Sulfargin (Tallinn Pharmaceutical Plant, Estonia) are creams whose active ingredient is sulfadiazine silver salt. They are produced in tubes of 40, 50 g, as well as in a jar of 250 g. They are used for the same indications as Argosulfan. In addition, this sulfonamide is active against Candida fungi and dermatophytes, as a result of which it can be prescribed for candidiasis and other skin mycoses;
  • Mafenida acetate ointment 10% comes in a package of 50 g per jar. The drug also has antifungal effect against Candida;
  • Streptocidal ointment and liniment of 5% and 10% is produced in a jar of 25 and 50 g. Indications for use are similar to Argosulfan.

Price for Argosulfan Cream

Argosulfan cream for external use 2%, tube 15 g - from 278 rubles.

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