The Ambroxol Syrup: instruction manual for children, price, reviews, analogues Ambroxol
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Ambroxol Syrup Instructions for Use

Ambroxol Syrup

Syrup Ambroxol is a representative of the pharmacological group of mucolytics and expectorants. It contains the active substance ambroxol hydrochloride, which reduces the viscosity of phlegm and facilitates its removal from the respiratory tract.

Form of issue and composition

The syrup is available in 100 ml vials. The bottle is made of dark glass to prevent exposure to light on the active substance. The cardboard package also contains a measuring spoon (5 ml volume). In 5 ml Ambroxol syrup contains 15 mg of ambroxol hydrochloride. Also in 1 ml of the drug contains so many auxiliary substances:

  • Benzoic acid 2 mg.
  • Gietilose (hydroxyethyl cellulose) - 1 mg.
  • Glycerol (85%) 127 mg.
  • Sorbitol (75%) - 250 mg.
  • Raspberry flavor is 2.5 mg.
  • Purified water - volume up to 1 ml.

The presence of a measuring spoon provides the convenience of dispensing and receiving syrup.

pharmachologic effect

The main active substance of the syrup Ambroxol belongs to the pharmacological group of expectorants and mucolytics. It has several therapeutic effects, which include:

  • Increased motor activity of cilia lining the mucous membrane of the respiratory tract (mucociliary clearance), which accelerates the excretion of sputum and various pathogenic agents (bacteria, viruses, chemical compounds, allergens).
  • Stimulation of production by cells of the mucous respiratory organs of enzymes, which catalyze the reaction of destruction of intramolecular bonds of mucopolysaccharides of sputum, due to which its viscosity decreases.
  • Increased activity of serous cells that produce liquid sputum.

These therapeutic effects of ambroxol hydrochloride facilitate the protective function of the mucous membrane of the airways. With improved sputum excretion, the cough becomes wet, then its intensity gradually decreases. After ingestion, the active substance is absorbed into the blood from the lumen of the small intestine. Therapeutic concentration is achieved only 20 minutes after taking the syrup. The necessary concentration in the mucosa of the respiratory tract remains for 6-12 hours. Then ambroxol hydrochloride is processed by liver cells with the formation of products of its decay, which are excreted by the kidneys with urine. The half-life of the active substance (the time during which half of the entire dose of the drug is excreted) is about 10 hours. Ambroxol penetrates into breast milk during lactation and into the fetus through the placenta during pregnancy.

Indications for use

The use of Ambrox syrup is indicated in the pathology of the respiratory system, in which viscous, thick sputum accumulates in the lumen of the bronchi. Such diseases include:

  • Bronchitis of infectious etiology caused by bacteria and viruses.
  • Tracheitis is an inflammation of the trachea of ​​various etiologies.
  • Pneumonia is an inflammation of the lungs, which most often develops as a result of the infectious process.
  • Bronchoectatic disease is the formation of bronchial anatomy (bronchiectasis) in which an inflammatory process develops and sputum accumulates.
  • Bronchial asthma and atopic bronchitis is an allergic inflammation of the bronchi, in which thick vitreous sputum is produced.
  • Obstructive bronchitis is a chronic inflammation accompanied by a narrowing (spasm) of the lumen of the bronchi and the accumulation of viscous sputum in them.
  • Cystic fibrosis is a genetic pathology with impaired sputum production processes, its quantity is small and differs by its high viscosity.

Due to its pharmacological properties, Ambroxol syrup is a pathogenetic component in the treatment of these diseases.

Contraindications for use

Syrup Ambroxol can not be taken in such cases:

  • Individual intolerance of ambroxol hydrochloride or other auxiliary components of the drug.
  • Early pregnancy (I trimester) - the penetration of ambroxol hydrochloride into the fetus through the placenta does not exclude its negative impact.
  • Congenital or acquired deficiency of enzymes in the digestive system, which catalyze the cleavage of fructose.
  • Ulcerous pathology of the mucous membrane of the duodenum or stomach - ambroxol hydrochloride can accelerate cell damage by reducing the protective properties of the mucosa of these organs.

The use of Ambroxol syrup on late terms (II and III trimester) of pregnancy and during breastfeeding is possible, but only on medical indications, which is determined by the doctor. At the same time, an analysis of the positive therapeutic effect on the mother's organism and the potential risk of developing negative consequences for the fetus or infant is necessarily carried out.

Method and dosage of Ambroxol Syrup for children

Syrup Ambroxol is taken internally in a certain volume, which can be controlled with a measuring spoon. The dosage of the drug depends on the severity of the course of the disease and the age of the patient. Recommended age-related dosages for children:

  • Age of the child from 2 to 6 years - ¼ of a measuring spoon (1.25 ml of syrup) 2-3 times a day (7.5-11.25 mg of ambroxol per day).
  • Age of the child from 6 to 12 years - ½ teaspoon (2.5 ml syrup) 3 times a day (daily dose of 22.5 mg ambroxol hydrochloride).
  • Age over 12 years - 1 measuring spoon (5 ml) 2-3 times a day (30-45 mg ambroksola hydrochloride per day).

The first 2-3 days from the onset of the disease is recommended to take the drug 3 times a day, then go to the maintenance dose with its reception 2 times a day. It is advisable to drink the syrup with plenty of water, which will improve the sputum liquefaction in the child and its subsequent excretion.


For children up to 2 years old, the doctor decides the question of using Ambrox syrup individually. He can prescribe the drug at a dosage of a ¼ teaspoonful 1-2 times a day, depending on the severity of the disease.
Independently give the drug to a child under 2 years is not recommended.

Side effects

In general, ambroxol syrup is well tolerated. In rare cases, it is possible to develop such side effects:

  • Allergic reactions in the form of a rash on the skin, its itching, urticaria (a characteristic rash in appearance resembling a nettle burn), angioedema, swelling of the skin and subcutaneous tissue ( Quincke's edema ). In severe cases of severe allergic reaction, anaphylactic shock can develop - a progressive decrease in blood pressure and multiple organ failure.
  • Dyspeptic syndrome - changes from the digestive tract, which manifest nausea, vomiting and stool disorder.
  • Increased excitability of the nervous system and changes in the reaction of the senses.
  • Dryness of the mucous membranes of the oral cavity, nasal cavity, pharynx, larynx and trachea.

Very rarely there are cases of development of pronounced skin changes, but their connection with the administration of ambroxol hydrochloride was not established precisely. In case of side effects, taking the drug should be stopped and seek medical help.

special instructions

Before you start using Ambroxol syrup, you should read his instructions. There are a number of points to pay attention to, they include:

  • The drug is taken after a meal, as it can have a negative effect on the gastrointestinal tract on an empty stomach.
  • Be sure, after taking the necessary amount of syrup, it must be washed with plenty of water to improve the dilution of sputum.
  • The average duration of taking Ambroxol syrup is 4-5 days, if it is necessary to prolong the course of treatment, it is necessary to consult a doctor.
  • Syrup Ambroxol can be combined with virtually all medicines of other pharmacological groups, with the exception of antitussives that cause sputum congestion in the airways.
  • The combined use of Ambroxol syrup and antibiotics enhances the efficacy of the latter by increasing their concentration in the airways.
  • With care, Syrup Ambroxol is used in the presence of concomitant liver and kidney pathology - it is desirable to conduct a laboratory control of the functional activity of these organs.
  • Ambroxol does not affect the reaction speed and concentration of attention, so it can be taken by people whose activities are associated with increased attention and reaction speed (transport drivers, work at altitude).

Syrup Ambroxol is a non-prescription drug, so it is dispensed without prescription in pharmacies. If there are any questions or doubts about its reception, you should consult a doctor.


Syrup Ambroxol have a wide dosage range. With a significant overdose, the development of a reaction from the digestive side (nausea, vomiting, diarrhea) and nervous (increased excitability) of the system is possible. In case of appearance of such symptoms, taking the drug is stopped, the stomach and intestines are washed. If necessary, detoxication therapy is applied (intravenous drip administration of adsorptive agents).

Terms and conditions of storage

The drug can be stored for no more than 2 years in a dark place inaccessible to children with an air temperature of no higher than 25 ° C.

Analogues of syrup Ambroxol

To similar preparations, which active substance is ambroxol hydrochloride, are: Ambrobe, Ambroghexal, Ambrolitin, Bronhoksol, Medox, Flavamed, Lazolvan.

The price of syrup Ambroxol

Ambroxol syrup, a bottle of 100 ml - from 81 rubles.

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