Allapinin: instructions for use
- Allapinin: instructions for use
Allapinin is a drug that is used to treat heart rhythm disturbances. It is an antiarrhythmic drug. Refers to class I C.
Form of issue, composition
The drug is available in the form of round tablets. Each tablet contains 25 mg of the main active substance - lappaconitin hydrobromide. Additional substances: sugar or sucrose, potato starch, calcium.
Available in contour boxes of 10 or 30 pieces. The cells are in cardboard packages.
Allapinin is also available in the form of a solution for intravenous and intramuscular injection.
Indications for use
Allapinin has a local anesthetic, sedative, moderate spasmolytic, coronary dilating and anticholinergic action.
The drug is recommended for use in the following pathologies:
- premature heart contractions (extrasystole);
- atrial flutter;
- bouts of increased heart rate;
- congenital pathologies, in which there are irregularities in the rhythm of cardiac contractions.
The intake of Allapinin is not possible with the following abnormalities or diseases:
- heart block, in which the hemodynamics of the heart is disturbed;
- severe or chronic liver or kidney disease;
- various heart diseases, which are accompanied by a rhythm disturbance;
- children under 18 years.
With extreme caution appoint patients with poor blood circulation. In this case, Allapinin appointed in a hospital, under the strict supervision of a doctor.
The drug is strictly prohibited for children and persons under the age of 18 years. There is no information about the effect of lappaconitin hydrobromide on children's body.
Mode of application
The drug in tablets should be taken according to the following scheme: before taking the tablet, it must be crushed, taken orally 30-40 minutes before eating, washed down with a glass of warm water.
The initial dose should not exceed 25 mg every 8 hours. On the recommendation of the attending physician, the dose of the drug can be increased to 50 mg every 7 hours.
The course of treatment directly depends on the specifics of the disease and symptoms. In more severe cases, treatment can last up to two months.
The maximum dose for oral administration: with a single admission - 50 mg, daily - 300 mg, the drug starts in 45-65 minutes. The effect of taking alapinin can last up to 7-8 hours.
Injection: iv injection is administered at 0.3 mg / kg. Before the injection, the drug must be dissolved in 20 ml of sodium chloride. The agent should be administered very slowly, for 5-7 minutes. If the therapeutic effect does not occur, then the dose can be repeated, but not earlier than 6 hours later.
With the / m introduction of the drug begins to act no sooner than 40-60 minutes, the therapeutic effect persists to 8 hours.
When treating this medication or with an incorrect dose, the following side effects are possible:
- dizziness, occasionally loss of consciousness;
- headache or heaviness in the head;
- blurred vision, dyslexia;
- in some cases, the onset of tachycardia, palpitation.
If such symptoms occur, the dose should be reduced. If improvement does not occur, you should consult your doctor to cancel or replace the medication.
The use of lactipine in combination with other antiarrhythmic drugs, even in small doses, can cause an overdose.
Treatment should be aimed at eliminating the symptoms.
Interaction with other drugs
With the simultaneous administration of Allapinin and inducers of microsomal liver enzymes, the therapeutic effect decreases. In some cases, the development of a toxic effect.
The drug is not recommended to be taken simultaneously with other antiarrhythmic drugs.
This medication enhances the effect of the muscle relaxants intended for relaxation of the striated musculature. It is necessary to consult a doctor if you can not cancel such funds.
Reception during pregnancy and lactation
This drug is not recommended for use during pregnancy. There is insufficient information about the effect of lappaconitin hydrobromide on the placenta and fetus.
During the course of treatment, breastfeeding should be canceled. It has the ability to penetrate breast milk.
If the patient has a history of abnormal water-electrolyte balance, then before beginning therapy with Allapinin, it must be eliminated.
During the period of treatment, it is necessary to conduct regular tests: a lipid spectrum, a blood test for proteins, glucose.
With caution, Allapin is prescribed to patients who have had myocardial infarction or have severe heart failure.
When side effects occur, the dosage reduces or abolishes the drug itself.
In the case of development of supraventricular tachyarrhythmia or tachycardia, the appointment of beta-blockers is indicated. These are the drugs that contain carbohydrates, the first dose should be minimal.
The drug is able to influence the ability to drive vehicles and work with heavy machinery. Therefore, patients working with transport and various mechanisms should be careful during the period of treatment.
Terms and conditions of storage
Keep in a cool place, protected from light and children. The drug can be consumed within 5 years of production. In the pharmacy, Allapinin is released on prescription. Self-medication is highly discouraged.
Analogues of Allapinin
To the analogs of the drug Allapinin include the following drugs:
The price of Allapinin
Allapinin tablets 0.025 grams, 30 pcs. - from 510 rubles.