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Allapinin: instructions for use

Allapinin: instructions for use

Allapinin is a drug used to treat heart rhythm disorders. It is an antiarrhythmic drug. Belongs to class I C.

Release form, composition

The drug is available in the form of round tablets. Each tablet contains 25 mg of the main active ingredient - lappaconitine hydrobromide. Additional substances: sugar or sucrose, potato starch, calcium.

Available in contour cells of 10 or 30 pieces. The cells are in cartons.

Allapinin is also available in the form of a solution for intravenous and intramuscular administration.

Indications for use

Allapinin has a local anesthetic, sedative, moderate antispasmodic, coronary-dilating and anticholinergic action.

The drug is recommended for use in the following pathologies:

  • premature heartbeats (extrasystoles);
  • atrial flutter;
  • bouts of increased heart rate;
  • congenital pathologies in which there are irregularities in the rhythm of heart contractions.


Reception Allapinina impossible with the following deviations or diseases:

  • heart block, in which the hemodynamics of the heart is disturbed;
  • severe or chronic liver or kidney disease;
  • various heart diseases that are accompanied by rhythm disturbances;
  • children under 18 years old.

With extreme caution prescribed to patients with poor blood circulation. In this case, Allapinin prescribed in the hospital, under the strict supervision of a doctor.

The drug is strictly prohibited to take children and persons under the age of 18 years. There is no information about the effect of lappaconitine hydrobromide on the child's body.

Mode of application

The drug in pills should be taken as follows: before taking the pill must be crushed, taken orally 30-40 minutes before a meal, with a glass of warm water.

The initial dose should not exceed 25 mg every 8 hours. On the recommendation of the attending physician, the dose of the drug may be increased to 50 mg every 7 hours.

The course of treatment depends on the specifics of the disease and symptoms. In more severe cases, treatment can last up to two months.

The maximum dose for oral administration: with a single dose - 50 mg daily - 300 mg, the effect of the drug begins after 45-65 minutes. The effect of taking allapinina can last up to 7-8 hours.

Injection: in / in the drug is administered at 0.3 mg / kg. Before injection, the drug must be dissolved in 20 ml of sodium chloride. The tool must be entered very slowly, within 5-7 minutes. If the therapeutic effect has not come, the dose can be repeated, but not earlier than after 6 hours.

When i / m administration, the drug begins to act no sooner than 40-60 minutes, the therapeutic effect lasts up to 8 hours.

Side effects  

When therapy with this drug or with an incorrect dose, the following side effects are possible:

  • dizziness, occasionally loss of consciousness;
  • headache or heaviness in the head;
  • blurred eyes, feeling of ghosting;
  • in some cases, possible tachycardia, palpitations.

In the event of such symptoms, the dose should be reduced. If there is no improvement, you should consult with your doctor to cancel or replace the medication.


The use of Allapinin in combination with other antiarrhythmic drugs even in small dosages can cause an overdose.

Treatment should be aimed at eliminating the symptoms that have arisen.

Interaction with other drugs

With the simultaneous use of Allapinin and inducers of microsomal liver enzymes, the therapeutic effect is reduced. In some cases, may develop toxic effects.

The drug is not recommended to be taken simultaneously with other antiarrhythmic drugs.

This medication enhances the action of the striated muscle muscles intended for relaxation of muscle relaxants. Consultation of the doctor is required if it is impossible to cancel such funds

Reception during pregnancy and lactation

This drug is not recommended to be taken during pregnancy. There is not enough information about the effect of lappaconitine hydrobromide on the placenta and fetus.

During the course of treatment, breastfeeding should be canceled. The tool has the ability to penetrate into breast milk.  

special instructions

If a patient has a history of water and electrolyte imbalance, then before starting therapy with Allapinin it should be corrected.

During the period of treatment, it is necessary to conduct regular analyzes: lipid profile, blood test for proteins, glucose.

With care, Allapinin is prescribed to patients who have suffered a myocardial infarction or have severe heart failure.

With the appearance of side effects, the dosage is reduced or canceled by the drug itself.

In the case of the development of supraventricular tachyarrhythmias or tachycardias, the appointment of beta-blockers is indicated. This means that contain carbohydrates, the first dose should be minimal.

The drug is able to influence the ability to drive vehicles and to work with heavy machinery. Therefore, patients working with transport and various mechanisms should be careful during the period of treatment.

Terms and conditions of storage

Store in a cool place, protected from light and children. The drug can be consumed within 5 years from the date of manufacture. In the pharmacy, Allapinin is released by prescription. Self-treatment is not recommended.

Anlapinin Analogs

The following drugs can be attributed to the analogues of the drug Allapinin:

  • Aymalin;
  • Difenin;
  • Trimecain;
  • Etatsizin;
  • Etmozin.

Price Allapinin

Allapinin tablets 0.025 g, 30 pcs.- from 510 rubles.

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