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Actovegin tablets: instructions for use

Actovegin tablets: instructions for use

Actovegin is used as a drug that activates the metabolism in tissues, as well as stimulates the regenerative process and improves trophism.

Composition and release form

The drug is available in the form of tablets, coated yellow-greenish. They are rounded, shiny.

It also produces the drug in the form of an injection for 40 mg / ml, 20% gel for topical use, 5% cream and ointment for external use.

The composition of one tablet includes 200 mg of deproteinized hemoderivat blood of calves. Auxiliary substances include: cellulose, magnesium stearate, talc and povidone K90.

The shell includes: macrogol 6000, mountain glycol wax, acacia gum, titanium dioxide, povidone K30, diethyl phthalate, sucrose, hypromellose phthalate, talc, quinoline dye yellow aluminum varnish.

Pharmacological properties

At the molecular level, this drug accelerates the utilization of glucose and oxygen, which, in turn, causes an increase in energy metabolism. The overall effect of these processes allows you to enhance the energy state of the cell, especially with ischemic lesions and hypoxia.

The effects of Actovegin on the body are very significant in the treatment of diabetic polyneuropathy.

Patients suffering from diabetic polyneuropathy (paresthesias, stitching pains, numbness of the lower extremities) and diabetes mellitus, during therapeutic interventions feel a decrease in the severity of sensory disturbances and improvement in mental well-being.

Since Actovegin contains physiological components, it is impossible to fully examine its pharmacokinetic characteristics.

Indications for use

This drug is recommended for use in such disorders:

  • Diabetic peripheral polyneuropathy;
  • Residual effects of hemorrhagic stroke;
  • Encephalopathies of various origins;
  • Ischemic stroke;
  • Traumatic brain injury;
  • Burn lesions 1-3 degrees;
  • Radiation neuropathy and various radiation damage to the skin;
  • Angiopathy;
  • Ulcers, bedsores, trophic disorders;
  • Disruption of the regeneration process;
  • Disturbance of peripheral venous or arterial blood circulation.

Mode of application

Tablets are recommended to be taken before meals, they should not be chewed, they should be washed down with plenty of running water. The recommended dose to take is 1-2 tablets 3 times a day. The course of treatment from 4 to 6 weeks.

The initial dose for diabetic polyneuropathy is 2 g / day for intravenous use for 3 weeks. After that, you can switch to pills with the use of 2-3 pieces per day, a course of about 4-5 months.

When parenteral administration may develop allergies, for this reason it is necessary to provide adequate conditions for the provision of emergency care to the patient.

Intravenous administered no more than 5 ml, which is provoked by the presence of hypertonic properties of the drug.

Gel treatment is carried out with radiation injuries, burns, ulcers. It is applied topically and covered with a compress. The dressing is changed once a week.

The cream is used for the treatment of weeping wounds. Can be used with pressure sores.

The local use of cream, ointment and body allows the skin to regenerate faster, which leads to the speedy healing of wounds and burns.

When treating the eyes, 1 drop of the gel is applied to the affected eye 2-3 times a day.

Contraindications to use

The only contraindications to the use of hypersensitivity to the components of the drug.

During breastfeeding and during pregnancy, the use of the drug is possible only when the benefit to the mother exceeds the threat to the fetus.

Side effects

Among the side effects from the application can be observed:

  • Puffiness;
  • Rapid breathing;
  • Nausea;
  • Sore throat;
  • Paresthesia;
  • Anaphylactic shock;
  • Acrocyanosis;
  • Weakness;
  • Diarrhea;
  • Headaches;
  • Pale skin;
  • Muscle soreness;
  • Urticaria ;
  • Tremor;
  • Hyperemia of the skin;
  • Arterial hypertension;
  • Pain in the lumbar region;
  • Choking attacks;
  • Temperature rise;
  • Pain syndromes in the epigastric region;
  • Excessive perspiration.

If any of the above symptoms manifest, you should stop using Actovegin and consult a specialist immediately.

special instructions

With the manifestation of various allergic manifestations, you must stop taking the medication. At the same time symptomatic therapy is carried out (use of GCS or antihistamines).

The behavior of experimental studies has shown that even a dose of 30-40 times the recommended one does not cause adverse reactions and toxic effects.

Since the manifestation of anaphylactic reactions is possible, a test injection must be carried out before use. For intramuscular administration, the medication should be administered slowly.

High-quality solution for intramuscular injection has a yellowish tint, with a different color is not desirable to carry out injections, in order to avoid negative consequences.

If you perform multiple manipulations, it is important to control the water-electrolyte balance.

The opened ampoule cannot be stored, but must be immediately thrown away.


When consuming a large amount of the drug, there are violations of the digestive tract. In such a situation, symptomatic therapy is carried out.

Interaction with other medicines

The interaction of the drug Actovegin with other drugs is not installed.

Drug storage

Keep the medication in a dark place at a temperature of 18-25 degrees. Shelf life - 3 years.

Prescription drug.

Analogs Actovegin


The price of tablets Actovegin

Actovegin coated tablets 200 mg, 50 pcs. - from 1500 rubles.

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