Actovegin tablets: instructions for use
- Actovegin tablets: instructions for use
Actovegin is used as a medicine that activates the metabolism in tissues, as well as stimulates the regenerative process and improves trophism.
Composition and form of release
The medication is available in the form of tablets, covered with a shell of yellow-greenish color. They have a rounded shape, shiny.
Also, the preparation is produced in the form of a solution for injection at 40 mg / ml, 20% gel for external use, 5% cream and ointment for external use.
The composition of one pill includes 200 mg of deproteinized hemodereal blood of calves. The auxiliary substances include: cellulose, magnesium stearate, talc and povidone K90.
The composition of the shell include: macrogol 6000, mountain glycolic wax, acacia gum, titanium dioxide, povidone K30, diethylphthalate, sucrose, hypromellose phthalate, talc, quinoline dye yellow aluminum lacquer.
At the molecular level, this drug helps accelerate the processes of utilization of glucose and oxygen, which, in turn, causes an increase in energy metabolism. The general effect of these processes makes it possible to strengthen the energy state of the cell, especially with ischemic lesions and hypoxia.
The specific effects of Actovegin on the body are very significant in the treatment of diabetic polyneuropathy.
Patients suffering from diabetic polyneuropathy (paresthesia, stitching, feeling of numbness of the lower extremities) and diabetes mellitus, undergoing therapeutic measures, feel a decrease in the severity of sensitive disorders and improvement of mental well-being.
Since Actovegin contains physiological components, it is impossible to study its pharmacokinetic characteristics to the end.
Indications for use
This drug is recommended for use in such disorders:
- Diabetic peripheral polyneuropathy;
- Residual phenomena of hemorrhagic stroke;
- Encephalopathy of various genesis;
- Ischemic stroke;
- Craniocerebral injury;
- Burning lesions of 1-3 degrees;
- Radiation neuropathy and various radiation damage to the skin;
- Ulcerative formations, bedsores, trophic disorders;
- Disorders of the regeneration process;
- Violation of peripheral venous or arterial blood circulation.
Mode of application
Tablets should be taken before meals, they should not be chewed, should be washed down with plenty of running water. The recommended dose to take is 1-2 tablets 3 times a day. The course of treatment is from 4 to 6 weeks.
The initial dose for diabetic polyneuropathy is 2 g / day for intravenous use for 3 weeks. After that, you can switch to tablets with the use of 2-3 pieces per day, the course of about 4-5 months.
With parenteral administration, it is possible to develop an allergy, for this reason it is worthwhile to ensure proper conditions for providing emergency care to the patient.
Intravenously injected no more than 5 ml, which is provoked by the presence of hypertonic properties in the drug.
Treatment with gel is carried out with radiation injuries, burns, ulcers. It is applied topically and covered with a compress. The bandage is changed once a week.
The cream is used to treat wet wounds. Can be used in the presence of pressure sores.
The local use of cream, ointment and body allows the skin to regenerate faster, which leads to the rapid healing of wounds and burns.
When treating the eye, 1 drop of gel is applied to the affected eye 2-3 times a day.
Contraindications to use
The only contraindications to use are hypersensitivity to the components of the drug.
In the period of breastfeeding and during pregnancy, the use of the drug is possible only if the benefit to the mother exceeds the threat to the fetus.
Among the side effects of the application can be observed:
- Increased respiration;
- Pain in the throat;
- Anaphylactic shock;
- Pale skin;
- Muscle soreness;
- Hives ;
- Hyperemia of the skin;
- Arterial hypertension;
- Pain in the lumbar region;
- Attacks of suffocation;
- Temperature increase;
- Pain syndromes in the epigastric region;
- Increased sweating.
If any of the above symptoms is manifested, stop using the drug Actovegin and urgently consult a specialist.
When allergies are different, stop taking the medication. In this case, symptomatic therapy (using GCS or antihistamines) is performed.
The behavior of experimental studies showed that even a dose 30-40 times higher than recommended does not cause adverse reactions and toxic effects.
Since anaphylactic reactions are possible, a test injection should be performed before use. When intramuscular injection should be administered slowly.
Quality solution for intramuscular injection has a yellowish tinge; in another color, it is not advisable to carry out injections, in order to avoid negative consequences.
If you conduct multiple manipulations, it is important to control the water-electrolyte balance.
The opened ampoule can not be stored, but must be discarded immediately.
When consuming a large amount of medicinal products, disturbances in the digestive tract are observed. In this situation, symptomatic therapy is performed.
Interaction with other medicines
The interaction of the drug Actovegin with other drugs has not been established.
Storage of the drug
Keep the medicine in a dark place at a temperature of 18-25 degrees. Shelf life - 3 years.
The medicine is released on prescription.
Analogues of Actovegin
Price for tablets Actovegin
Actovegin tablets, coated with 200 mg, 50 pcs. - from 1500 rubles.