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Actovegin cream instructions for use

Actovegin cream instructions for use

Actovegin cream is a drug for external use, which improves and accelerates the healing process of tissues and stimulates regeneration.

Release form

Actovegin cream is available in aluminum tubes of 20, 30, 50 and 100 g. The tube is packed in a cardboard box.

The composition of the drug

Actovegin cream is a uniform thick substance for external use of white color, which has no strong or peculiar smell. 100 grams of cream contains:

The main active ingredient is deproteinized calf-blood hemoderivate 5 ml, which, on the basis of dry weight, is about 0.2 g.

Auxiliary components: glyceryl, purified water, benzalkonium hydrochloride, momnostearate, macrogol, cetyl alcohol.

Pharmacological properties of the drug

Actovegin cream promotes the activation of metabolic processes in tissues, which leads to a significant improvement in regeneration processes. When applying the cream on the skin surface, cellular metabolism is activated by increasing the supply and accumulation of glucose and oxygen by the cells. This process causes the acceleration and enhancement of ATP production processes, which increases the energy abilities of cells. Actovegin cream also increases blood circulation in this area when applied to the skin.

Pharmacokinetic properties

In the course of the clinical trials of the drug, it was found that when applied to the skin, cream Actovegin is practically not absorbed into the general bloodstream, which is especially important for people with disorders in the kidneys, liver or other internal organs.

Indications for use

The main indications for topical use of Actovegin cream are:

  • Varicose veins of the lower extremities, which is accompanied by neglected trophic ulcers of the skin or other disorders of the peripheral circulation;
  • Bedsores in bedridden patients who are poorly treatable with other local treatments;
  • Microcracks of the skin;
  • Wounds and ulcers of the skin of various origins;
  • Skin lesions that were formed under the influence of radiation therapy in cancer patients;
  • Burns 1.2 degrees.

Methods of use and dosage of the drug

Actovegin cream is intended for external use. Before applying the drug on the skin, you need to make sure that they are clean. For the treatment of skin burns, cracks or lesions on the background of radiation therapy a sufficiently thin layer of cream, which is applied 2 times a day.

If necessary, regeneration of the skin with open deep ulcers and wounds Actovegin cream is applied twice a day with a thick layer, after which the lesion is covered with a sterile or just clean gauze bandage. This is necessary in order to prevent dust and dirt from entering the wound. When weeping wounds and ulcers, this procedure should be done not twice a day, but three times after pre-treatment of the affected area with hydrogen peroxide or another antiseptic.

Actovegin cream perfectly heals skin burns and minor wounds, moreover, the active ingredient of the drug prevents the appearance of scars on the skin, provided the treatment is started correctly and in time.

In order to prevent pressure sores in a bed patient, Actovegin is applied 2-3 times a day while turning the patient in bed, massaging the skin, changing bed or underwear.

To prevent the appearance of skin lesions on the background of radiation therapy Actovegin cream is applied to the exposed areas with a thin layer immediately after the end of the session of therapy or in between courses.

The duration of drug therapy is determined by the doctor, but, as a rule, the use of Actovegin does not exceed 10-14 days.

Side effects

As a rule, Actovegin cream is well tolerated by the patient, even with a slight increase in dose. In some cases, people with hypersensitivity of the skin or individual intolerance of one of the components of the drug may have the following manifestations:

  • Redness of the skin in places of application;
  • Unpleasant sensations on the skin - itching, burning;
  • Very rarely can hives develop.


The only contraindication to the use of Actovegin cream is hypersensitivity or individual intolerance to the main active ingredient or auxiliary components of the tool.

The possibility of using the drug during pregnancy or breastfeeding

Use of Actovegin cream in the waiting period of the child is possible only in the case when the expected benefit for the future mother outweighs the potential risks to the fetus. The use of this drug should be carried out under the supervision of a physician.

The use of Actovegin cream during breastfeeding of a child is possible in the absence of individual intolerance to the components of the drug, both in the mother and the child, since the minimum number of active substances is still absorbed through the skin and can penetrate into breast milk in micro doses.

Interaction with other drugs

Use of Actovegin cream is possible in parallel with other medicinal substances that do not contain the same components. For the rest, no other medicinal substances of internal and external influence inhibit the therapeutic effect of Actovegin.

Drug overdose

Currently, there are no data on overdose cases in the local use of Actovegin cream, but in order to prevent the development of the above side effects, do not exceed the doses indicated in the instructions.

Drug storage conditions and terms

Cream Actovegin 5% sold in pharmacies without a prescription. After opening the tube, the drug should be stored in a refrigerator or a dark, cool place out of the reach of children for months. An unpainted tube can be stored for more than 3 years at a temperature not higher than 25 degrees. The cap of the packaging after using the cream should be tightly tightened.

Analogs Actovegin cream


Price Actovegin cream

Actovegin cream for external use of 5%, tube 20 g - 114 rubles.

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