The Actovegin cream: user manual, price, reviews, analogues of Actovegin
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Actovegin cream instructions for use

Actovegin cream instructions for use

Cream Actovegin is a medicinal product for external use that improves and speeds up the process of tissue healing and stimulates regeneration.

Form of issue

Actovegin cream is available in aluminum tubes of 20, 30, 50 and 100 g. The tube is packed in a cardboard box.

Structure of the preparation

Actovegin cream is a homogeneous, thick substance for external application of white color, which does not have any sharp or specific odor. In 100 grams of cream contains:

The main active ingredient is deproteinized calf blood calf hemoderivat 5 ml, which is about 0.2 g at the dry weight calculation.

Auxiliary components: glyceryl, purified water, benzalkonium hydrochloride, monostearate, macrogol, cetyl alcohol.

Pharmacological properties of the drug

Actovegin cream promotes the activation of metabolic processes in tissues, which leads to a significant improvement in regeneration processes. When the cream is applied to the skin surface, the cellular metabolism is activated by increasing the supply and accumulation of glucose and oxygen by the cells. This process causes the acceleration and intensification of the processes of ATP generation, which increases the energy capacities of the cells. Also Actovegin cream when applied to the skin strengthens the blood circulation in this area.

Pharmacokinetic properties

In the course of clinical trials of the drug it was found that when applied to the skin, Actovegin is practically not absorbed into the common bloodstream, which is especially important for people who have disorders in the work of the kidneys, liver or other internal organs.

Indications for use

The main indications for external use of Actovegin cream are:

  • Varicose veins of the lower extremities, which is accompanied by neglected trophic skin ulcers or other disorders of the peripheral circulation;
  • Bedsores in bedridden patients, which are difficult to treat with other drugs of local influence;
  • Microcracks of the skin;
  • Wounds and ulcerative skin of various origin;
  • Skin lesions, which were formed under the influence of radiation therapy in cancer patients;
  • Burns of 1,2 degrees.

Methods of application and dosage of the drug

Actovegin cream is for external use. Before applying the drug on the skin, you need to make sure that they are clean. To treat skin burns, cracks or lesions on the background of radiation therapy, a thin layer of cream is applied, which is applied 2 times a day.

If it is necessary to regenerate the skin with open deep ulcers and wounds, Actovegin cream is applied twice a day in a thick layer, after which the lesion is covered with a sterile or simply clean gauze dressing. This is necessary in order to prevent the ingress of dust and dirt into the wound. When wet wounds and ulcers, this procedure should be done not twice a day, but three times after pretreatment of the affected area with hydrogen peroxide or another antiseptic.

Actovegin cream perfectly heals skin burns and minor wounds, moreover, the active substance of the drug prevents the appearance of scars on the skin, provided that the treatment is properly and timely started.

For the purpose of prophylaxis of pressure sores, the patient has an infusion of Actovegin cream 2-3 times a day during the inverting of the patient in bed, skin massage, changing of bed or underwear.

To prevent the appearance of skin lesions on the background of radiotherapy, Actovegin cream is applied to the exposed areas with a thin layer immediately after the end of the therapy session or in the intervals between courses.

The duration of therapy is determined by the doctor, but as a rule, the use of Actovegin does not exceed 10-14 days.

Side effects

As a rule, Actovegin cream is well tolerated even with a slight increase in the dose. In some cases, in people with increased skin sensitivity or individual intolerance to one of the components of the drug, the following manifestations are possible:

  • Redness of the skin at the site of application;
  • Unpleasant sensations on the skin - itching, burning;
  • Very rarely hives develop.

Contraindications for use

The only contraindication to the use of Actovegin cream is hypersensitivity or individual intolerance of the main active substance or auxiliary components of the drug.

The possibility of using the drug during pregnancy or breastfeeding

The use of Actovegin cream during the waiting period of the baby is possible only if the expected benefit for the expectant mother exceeds the potential risks to the fetus. The use of this drug should be done under the supervision of a doctor.

The use of Actovegin cream in the period of baby breastfeeding is possible in the absence of individual intolerance to the components of the drug, both in the mother and the child, since the minimum amount of active substances is still absorbed through the skin and can penetrate into the breast milk in microdoses.

Interaction with other medicinal products

The use of Actovegin cream is possible in parallel with other medicinal substances that do not contain the same components. In other respects, no other medicinal substances of internal and external influence inhibit the therapeutic effect of Actovegin.

Overdose of the drug

Currently, there are no data on cases of overdose with topical use of Actovegin cream, but in order to prevent the development of the above side effects, do not exceed the dose specified in the instructions.

Conditions for storage of the preparation and terms

Cream Actovegin 5% is dispensed in pharmacies without a prescription. After opening the tube, the drug should be stored in a refrigerator or in a dark cool place inaccessible to children for months. Unopened tube can be stored for more than 3 years at a temperature of no higher than 25 degrees. The packing cap should be tightly tightened after using the cream.

Analogues Actovegin cream


Price for Actovegin cream

Actovegin cream for external use 5%, tube 20 g. - 114 rub.

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