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Aktiferrin drops instructions for use

Aktiferrin drops instructions for use Aktiferrin drops refers to a group of medicinal substances that increase the level of iron in the human body.

The composition of the drug

Aktiferrin is available in several forms. Drops for ingestion are a clear liquid with a brownish or yellow-greenish tint, with a raspberry smell.

1 ml of drops contains 47 mg of iron sulphate heptagrirate, as well as excipients - ascorbic acid, ethanol 96%, flavoring raspberry, purified water, potassium sorbate.

Pharmacological properties of the drug

Actiferrin drops for oral administration are designed to compensate for iron deficiency in the body. Iron is a very important trace element and is part of hemoglobin - a protein that transports oxygen to all organs and tissues and stimulates the formation of red blood cells. The composition of Aktiferrin contains alpha-amino acid serine, which improves the absorption of iron by the body and helps to quickly restore its optimal level in the blood. As the patient's iron deficiency is replenished, symptoms of anemia such as weakness, pallor of the skin, dizziness, and rapid heartbeat gradually disappear.

Pharmacokinetic properties

After taking the drops inside, the iron contained in the preparation is maximally absorbed by the walls of the small intestine and enters the systemic circulation. The maximum concentration of the drug in the blood is reached in about 3-4 hours after administration. Undigested iron is excreted along with urine and feces, as a result of which the stool may turn black.

The main indications for the use of the drug

The drug Aktiferrin prescribed to patients in such cases:

  • Severe iron deficiency anemia of various origin - most often develops in pregnant women, with significant blood loss, with inadequate or monotonous nutrition, with frequent viral infections and weak immunity;
  • In order to prevent anemia with constant blood donation;
  • Chronic gastritis with secretory insufficiency, as a result of which microelements and vitamins necessary for the body cannot be completely absorbed from food;
  • The transferred operations, as a result of which the patient can not yet eat a balanced and complete;
  • Tumors of the esophagus, intestines, pancreas, which leads to impaired absorption of iron;
  • Breastfeeding period for women.

Methods of use and dosage

Actiferrin in the form of drops can be prescribed even to newborns who were born prematurely, with congenital abnormalities of the digestive system organs, or who have adapted milk formula from the first days of life. The dosage is calculated on 5 drops per 1 kg of body weight of the child.

For therapeutic purposes, Actiferrin is prescribed in the following dosages:

  • Newborn babies - 10-15 drops three times a day;
  • Children of younger preschool age (from 1 to 3 years) - 25-30 drops three times a day;
  • School-age children (from 7 to 12 years old) - 50 drops three times a day.

The duration of use of Actiferrin is determined only by a doctor, based on the indicators of the blood test and the general condition of the patient, but in order to replenish the stores of iron drops should be taken at least 2-3 months. During this period, the body usually replenishes iron deficiency and creates certain of its reserves. After normalization of blood counts, the patient moves to a maintenance dose of the drug.

In order for the body to absorb iron as much as possible, it is necessary to know some features of the drug intake. I take Aktiferrin 1 hour before meals or 2-3 hours after meals, with drops of acidic water, orange juice or plain clean water.

Side effects

With uncontrolled use of Aktiferrin or self-excess of the dose indicated by the doctor, the patient may develop the following side effects:

  • The appearance of metallic taste in the mouth;
  • Violations of the stool, in particular the development of persistent constipation;
  • Abdominal distention;
  • Epigastric pain;
  • Nausea and sometimes vomiting;
  • Pain in the right hypochondrium;
  • Headaches and dizziness;
  • Allergic skin reactions: rash, itching, urticaria , in rare cases, the development of angioedema or anaphylactic shock;
  • Discomfort in the sternum.

As a rule, the drug is very well tolerated and with proper dosage compliance such phenomena do not occur. If you experience side effects, you must stop taking the drug and consult a doctor. In most cases, to normalize the condition, it is enough to reduce the dose.

Interaction with other drugs

When using Actiferrin, it is important to remember that certain drugs can significantly reduce iron absorption by the small intestine. These include drugs containing calcium, antacid substances, enzymes (pancreatin, mezim, festal and others), penicillins, tetracyclines, drugs, which include oxalates, phosphates, carbonates.

In addition, some foods and beverages can also significantly reduce iron absorption, such as milk, eggs, bananas, cottage cheese, cream, cheese, coffee, and caffeine containing beverages. The interval between taking iron supplements and these products should be 1-2 hours.

The absorption of iron preparations increases with the simultaneous use of Aktiferrin with ascorbic acid or ethanol, but this also increases the risk of side effects.


Drug overdose

If Actiferrin is used improperly and the dosage indicated by the doctor itself is exceeded, the following symptoms may develop:

  • Growing weakness;
  • Pallor of the skin;
  • Protrusion cold sticky sweat;
  • Cardiopalmus;
  • Enlarged liver and spleen;
  • Weak thready pulse;
  • Reduced blood pressure;
  • The blueness of the tips of the ears, nose, fingers and toes;
  • Increased body temperature;
  • Bouts of convulsions;
  • A state of inhibition, as a result of which the patient may fall into a coma.

In the absence of timely medical care, the patient develops acute renal and hepatic necrosis and death within 1-3 days.

Treatment of iron overdose

The main antidote Actiferrin is Deferoxamine. When symptoms of an overdose of iron preparations appear, the patient should stop taking them, give orally to drink milk or raw eggs, wash the stomach, make a cleansing enema with soda. In case of severe poisoning with Actiferrin, the patient is injected parenterally with Deferoxamine, after having dissolved 10-20 ampoules of the drug in clean drinking water.

To speed up the removal of iron from the body, hemodialysis can be used, but it is not suitable as an independent method of treating Aktiferrin overdose.

Use of the drug during pregnancy and during breastfeeding

During the period of carrying a child, women regularly undergo blood tests. At the first symptoms of anemia and a decrease in iron in the blood test, it is advisable to use Aktiferrin. The dose of the drug and the duration of therapy are determined by the doctor, depending on the severity of iron deficiency and the general condition of the woman.

During the breastfeeding period, the child, together with milk, sucks out all the useful trace elements and vitamins from the mother's body, so for the prevention of anemia in mom and baby it is advisable to use Aktiferrin. In the absence of iron deficiency in order to prevent anemia, a maintenance dose is enough, which is determined individually for each woman.

Release form and storage conditions

Actiferrin is available in the form of drops for oral administration in a 30 ml vial of dark glass.

The drug should be kept in a dark, cool place out of the reach of children. After opening the bottle, Actiferrin is suitable for 1 month.

Precautionary measures

Aktiferrin drops with caution should be taken in patients with inflammatory diseases of the small intestine, with gastric ulcer, hepatitis, renal failure or diseases of the joints.

Aktiferrin drops should be taken after diluting the drug with a small amount of water or other suitable liquid, otherwise staining of the tooth enamel in a dark color is possible.

Analogues of Aktiferrin

Structural analogues currently no.

Analogs with a similar action: Ferroplex, Totem, Sorbifer, Ferrum-lek, Ferlatum, Venofer, Maltofer, Heferol, Memorin, Fenuls etc.

Price for Aktiferrin

Aktiferrin drops for oral administration, a bottle of 30 ml - from 300 rubles.

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