- Acyclovir tablets
- Form of formulation and composition of the preparation
- Indications for use
- Contraindications for use
- Use of the drug during pregnancy and breastfeeding
- Side effects
- Dosing and Administration
- special instructions
- Interaction of acyclovir with other drugs
- Conditions of leave in pharmacies and storage of medicines
- Acyclovir tablet analogs
- Acyclovir tablets price
The drug acyclovir is an antiviral agent for internal use that is active against the viruses of the herpes simplex group, genital herpes and shingles.
Form of formulation and composition of the preparation
Acyclovir is available in the form of tablets intended for oral use at a dosage of 0.2 g. The tablets are packed in a cardboard box of 20 pieces.
The main active substance of the drug is acyclovir.
Indications for use
Acyclovir tablets are prescribed to patients for the treatment of such pathologies:
- Herpetic infections of the skin due to herpes simplex virus types 1 and 2;
- Herpes reproductive tract;
- Herpetic rashes on the skin and mucous membranes of the oral cavity in patients with severe immunodeficiency;
- Shingles as part of complex therapy.
Contraindications for use
The drug based on acyclovir is not assigned to patients with an individual hypersensitivity to the main active ingredient and people suffering from kidney failure.
Use of the drug during pregnancy and breastfeeding
The use of tablets based on acyclovir in the first trimester of pregnancy is contraindicated. The active substances of the drug easily penetrate the placental barrier to the fetus and, although there is no data on the teratogenic effect of acyclovir on the embryo, it is not recommended to take it for treatment of women at this time. In the first 12 weeks, the fetus is laid down all internal organs and systems, and the influence of any medicine on the body can lead to violations of this delicate process.
The use of this drug in the 2nd and 3rd trimester is possible after a careful assessment of the potential risk to the fetus and benefit to the mother. Acyclovir tablets are used to treat future mothers with herpes infection only under the strict supervision of a doctor. It is completely unacceptable to self-medicate the drug.
At the time of breastfeeding, use Acyclovir tablets should be taken with extreme caution. Getting inside the active substance of the drug penetrates into breast milk, and in the process of feeding and into the body of the child. Data on the safety of this drug and its effect on the body of infants in medicine, no, so a woman should consult a doctor before starting therapy. Perhaps, for this period the child should be temporarily transferred to artificial feeding with milk formula.
This drug is well tolerated by patients with careful adherence to the prescribed dose. In rare cases, with a significant excess of the daily dose of the drug, the patient may develop the following side effects:
- On the part of the organs of the digestive canal - lack of appetite, nausea, abdominal pain, vomiting, diarrhea;
- From the side of the central nervous system - headache, dizziness, convulsions , tremor of hands, depression of consciousness or, conversely, mental and emotional overexcitation, drowsiness, apathy to what is happening, malaise and general weakness;
- From the cardiovascular system - increased heart rate, lower blood pressure, dyspnea;
- From the side of urinary organs - the development of acute renal failure with the use of the drug in high doses;
- Allergic skin reactions, hives , Quincke's edema , in very rare cases anaphylactic shock;
- Muscle pain, paresthesia.
Dosing and Administration
Acyclovir tablets are taken orally during meals or immediately after meals. It is recommended to drink the drug with a sufficient amount of liquid. The dosage of the drug and the duration of the course of therapy are determined by the doctor on the basis of blood tests and a clinical picture of the disease.
In herpetic lesions with severe course for the treatment of adults, Acyclovir tablets are prescribed 200 mg 4-5 times a day at regular intervals. The course of treatment should not exceed 10 days. If there is no improvement during this time, t the patient should consult a doctor once again to clarify the diagnosis and the adequacy of the therapy.
During the period of treatment with this drug should provide sufficient fluid intake in the body. This is due to the fact that acyclovir can precipitate and settle in the tubules of the kidneys, which leads to disturbances in the work of urinary organs and kidney failure, in severe cases. The drug is administered with caution to treat patients with impaired renal function or severe neurological pathologies.
Patients suffering from impaired liver function and electrolyte balance, this drug is prescribed in the lowest effective dosages and under strict medical supervision.
The drug is not prescribed for the treatment of varicella in children, if the disease is mild.
This drug is not used to treat children under 3 years old. With special care, the medicine is prescribed for elderly people.
Interaction of acyclovir with other drugs
With the simultaneous use of drugs based on Acyclovir with immunomodulators, their therapeutic effect is enhanced.
With the simultaneous use of a drug against herpes with tetracycline antibiotics, macrolides and cephalosporins, the risk of side effects from the urinary organs increases. This should be taken into account and with caution to use this drug along with antibiotics.
Conditions of leave in pharmacies and storage of medicines
Acyclovir tablets are dispensed in pharmacies without a prescription. The drug should be stored in a place protected from children at a temperature of no more than 25 degrees, avoiding direct sunlight on the packaging. Shelf life of the tablets is 2 years from the date of manufacture, which is indicated on the package. At the end of this period, tablets should not be taken orally.
Acyclovir tablet analogs
Analogues for the active ingredient: Vivorax, Virolex, Gervirax, Herperax, Herpesin, Zovirax, Lizavir, Medovir, Provirsan, Supperan, Cyclovax, Ciclovir, Cytivir.
Acyclovir tablets price
Acyclovir tablets 200 mg - from 19 rubles.