The Acyclovir Cream: user manual, price, reviews, analogs of cream Acyclovir
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Acyclovir Cream Instructions for Use

Acyclovir Cream Instructions for Use

Cream Acyclovir is an antiviral agent for external use. It has a therapeutic effect in various herpes infections by blocking the replication of viruses.

Form of issue and composition

Cream Acyclovir for external use is available in tubes of 5 g. The active substance of the drug is acyclovir, its concentration is 5% (1 mg of ointment contains 5 mg of acyclovir). In addition to the active substance, the cream contains auxiliary components, which include:

  • Medical Vaseline Oil.
  • Cetostearyl alcohol of emulsifying type A.
  • Poloxamer 407.
  • Propylene glycol.
  • Dimethicone.
  • Purified water.

In one cardboard pack of the drug contains 1 tube with 5 g of cream and instruction for its use. The concentration of the active substance is sufficient to block the replication of the viruses.

pharmachologic effect

The active substance of the drug acyclovir is an analogue of thymidine nucleoside. Its mechanism of action is that after penetration into the infected cell, the viral enzyme thymidine kinase catalyzes the conversion of acyclovir into acyclovir triphosphate, which is embedded in the genetic material of the virus (DNA) and prevents the reading of information (transcription), which leads to blocking the transcription process (formation and assembly of new virus particles). In healthy cells not infected with the virus, the enzyme thymidine kinase is absent, therefore acyclovir does not become a form of triphosphate and does not adversely affect the genetic material of the cell. The virus shows the greatest activity with respect to herpes simplex viruses (Herpes simplex) and herpes zoster (Varicella zoster). A smaller effect, the active substance of the drug has on cytomegalovirus and the Epstein-Barr virus.

When applied externally, the active ingredient of the cream Acyclovir is well adsorbed by the cells of the skin and mucous membranes in the area of ​​its application. Acyclovir is not absorbed into the systemic circulation.

Indications for use

Cream Acyclovir is indicated for the treatment of cutaneous manifestations of various herpetic infections, which include:

  • Herpes with rashes on the skin in the area of ​​the lips, genitals and other areas of the body.
  • Tinea with the development of a characteristic rash on the skin, corresponding to the innervation of the nerve affected by the viral infection. After applying the cream, Acyclovir, the severity of the rash and the intensity of pain are reduced.
  • Varicella is an infectious viral process with the appearance of a rash all over the body in the form of small bubbles filled with liquid.

It is not recommended to apply Acyclovir cream to the mucous membranes of the body.

Contraindications for use

Use of the cream Acyclovir is contraindicated in case of development of individual intolerance to the main active substance of the drug or its auxiliary components. It is also not recommended to apply cream in the presence of allergic reactions, which are mainly manifested by changes in the skin in the form of rash, itching or rash development on the background of swelling of the skin, which resembles a nettle burn ( urticaria ).

Dosage and route of administration

Cream Acyclovir is a drug for external use. It is applied to the affected area of ​​the skin, on which there are elements of the rash, indicating the presence of a herpetic infection. It is also possible to apply the drug in the area of ​​herpes of the lips and genitals. Multiplicity of application of the cream - 5 times a day, with an interval between application in 4 hours. The duration of treatment is an average of 5 days. If during this time, the improvement of the skin, the intensity and severity of the rash did not occur, then the treatment course can be prolonged up to 10 days.

Side effects

Cream Acyclovir is generally well tolerated, this is due to the lack of intake of the active substance into the systemic circulation. It is possible to develop skin allergic reactions after applying a cream on it, which manifests itself in the form of erythema (redness of the skin), rash, itching or urticaria. In rare cases, the development of angioedema angioedema (pronounced swelling of the skin and subcutaneous tissue, with a predominant localization in the face and genital organs) is possible. In case of side effects, the drug should be discontinued.

special instructions

Before you start using Acyclovir, you should read the instructions for use, which is enclosed in a cardboard box. It is important to pay attention to such special instructions:

  • You can not use Acyclovir Cream to treat herpetic infection of the eyes (keratitis), for this there is a special dosage form of the drug - ophthalmic ointment.
  • In the absence of the effect of treatment, consultation with a dermatologist or infectious disease specialist is necessary to decide on the use of antiviral drugs of systemic action (taking in the form of tablets).
  • It is allowed to apply Acyclovir cream to pregnant women and during breastfeeding, as the active substance of the drug is not absorbed into the systemic bloodstream.

In the chemist's network, Acyclovir cream is dispensed without a prescription. In case of any questions or doubts, it is advisable to consult a doctor. During the treatment of herpes lips, it is necessary to follow the recommendations regarding the prevention of infection of this infection by healthy people (individual utensils and personal hygiene items).


Due to the fact that the active substance of the drug is not absorbed into the systemic circulation, cases of overdose are unknown. Sometimes, with significant application to the skin, it is possible to develop side effects in the form of erythema and allergic reactions.


Similar drugs, which contain the same active substance, are - Ациклопедид, Виворакс, Герпевир, Герперакс, Зовиракс.

Terms and conditions of storage

Shelf life of the drug since its manufacture is 2 years. After unpacking the package and using the ointment, its shelf life is 30 days. Store the Acyclovir cream in a dark place inaccessible to children with an air temperature of + 15-25 ° C.

Cream Acyclovir price

Acyclovir cream for topical and topical application 5%; Tube aluminum 5 g - from 27 rub.

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