The Acetylsalicylic acid: instructions for use, which helps, how to take, reviews, tablet analogs Acetylsalicylic acid
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Acetylsalicylic acid

Acetylsalicylic acid tablets

Acetylsalicylic acid or aspirin belongs to the group of non-steroidal anti-inflammatory drugs and has a pronounced antipyretic, analgesic and antiaggregant properties.

Form of the preparation

Acetylsalicylic acid is available in the form of round tablets with a horizontal strip in the middle of white. The drug is packed in blisters or paper packages of 10 pieces.

Pharmacological properties of the drug

Acetylsalicylic acid when ingested induces a violation of the synthesis of prostaglandins, substances that play a major role in the development of fever, inflammatory processes and pain syndrome.

Suppressing the production of prostaglandins leads to an expansion of the blood vessels, which contributes to strengthening the separation of sweat, which explains the antipyretic effect of the drug.

The use of drugs based on acetylsalicylic acid in the therapy leads to a decrease in the sensitivity of nerve endings, which explains the pronounced analgesic effect of this drug. Acetylsalicylic acid is excreted from the body through the kidneys.

What helps acetylsalicylic acid

Tablets of acetylsalicylic acid are prescribed for adults with the purpose of treatment and prevention of the following conditions:

  • Acute inflammatory processes - inflammation of the cardiac sac, rheumatoid arthritis , small chorea, pneumonia and pleurisy as part of complex therapy, inflammatory lesions of the periarticular bag;
  • Pain syndrome of various origins - severe headaches, toothache, muscle aches with influenza and viral infections, menstrual pain, migraines, joint pain;
  • Diseases of the spinal column, accompanied by severe pain syndrome - osteochondrosis, lumbago;
  • Increased body temperature, fever due to infectious and inflammatory processes in the body;
  • Prevention of the development of myocardial infarction or ischemic stroke in cases of circulatory disorders, thromboaggregation, heavily dense blood;
  • Stenocardia of unstable nature;
  • Genetic predisposition to thromboembolism, thrombophlebitis;
  • Heart defects, mitral valve prolapse (disruption of its functioning);
  • Pulmonary infarction, thromboembolism of the pulmonary artery.

Contraindications for use

Tablets of acetylsalicylic acid have a number of contraindications to use. These include:

  • Hemorrhagic diathesis and vasculitis;
  • Gastritis of erosive or corrosive origin;
  • Peptic ulcer of the stomach and duodenum;
  • Poor blood clotting, tendency to bleeding;
  • Insufficiency of vitamin K;
  • Dissecting aneurysm of the aorta;
  • Severe disorders in the kidney and liver;
  • Hemophilia;
  • Individual intolerance to salicylates or allergic reactions to acetylsalicylic acid in the anamnesis;
  • Arterial hypertension, the risk of hemorrhagic stroke.

Acetylsalicylic acid, how to take?

Tablets of acetylsalicylic acid are intended for oral administration. It is recommended to take the drug at the beginning of the meal or immediately after a meal in order to prevent the development of erosion on the gastric mucosa. Tablets can be washed down with milk, so the irritating effect of acetylsalicylic acid on the mucous membranes of the digestive tract will not be as aggressive or use ordinary alkaline water without gas in sufficient quantities.

Adults appoint 1 tablet of 500 mg of the drug 2-4 times a day, depending on the indications and general health. The maximum daily dose is 3 g and can not exceed it! The duration of therapy with this medication is determined by the doctor depending on the indications, the severity of the inflammatory process and the individual characteristics of the organism, but this period should not exceed 10-12 days.

For preventive purposes, to decrease the risk of developing myocardial infarction and thromboaggregation, adults are prescribed ½ aspirin tablets once a day. The duration of therapy is about 1-2 months. During this period, it is necessary to constantly monitor the clinical picture of blood, monitor the rate of blood clotting and the number of platelets.

Adverse Events

Before starting the use of acetylsalicylic acid tablets, the patient should consult a doctor. If the dose is exceeded or uncontrolled and prolonged use of this drug, the following side effects may develop:

  • Pain in the epigastric region, nausea, vomiting;
  • Diarrhea;
  • Dizziness and weakness;
  • Loss of appetite;
  • Visual impairment;
  • Bleeding - intestinal, nasal, gingival, gastric;
  • Change in the clinical picture of blood - a decrease in the number of hemoglobin and platelets;
  • Disturbances in the liver and kidneys;
  • Development of acute renal failure;
  • Bronchospasm, in severe cases, development of angioedema and anaphylactic shock.

Use of the drug during pregnancy and lactation

The drug acetylsalicylic acid is forbidden to take in the 1 and 3 trimesters of pregnancy.

According to the studies, the use of aspirin tablets in pregnant women in the first 12 weeks greatly increases the risk of anomalies in the embryo, namely, the cleft of the upper palate and congenital heart defects.

The use of the drug in the 2nd trimester is possible with special care and only if the expected benefit for the mother will be higher than the possible harm to the fetus. Tablets are used in a strictly indicated dosage (minimally effective) and under strict medical supervision. During the treatment of a future mother, you must regularly take a blood test to assess hematocrit and platelet count.

Use of acetylsalicylic acid in the 3rd trimester is prohibited because of the huge risk of early closure of the aortic duct in the fetus. In addition, the drug can lead to hemorrhages in the ventricles of the brain in the fetus and cause a risk of massive bleeding in the future mother.

The use of acetylsalicylic acid tablets during breastfeeding is prohibited because of the high risk of developing hepatic and kidney failure in a child. In addition, getting into the body of the baby with the mother's milk, acetylsalicylic acid can lead to severe internal bleeding in the child. If it is necessary to use this drug during the breastfeeding period, the baby should be transferred to artificial feeding with a milk adapted mixture.

Interaction with other medicinal products

The simultaneous use of aspirin tablets with other drugs from the group of non-steroidal anti-inflammatory substances (ibuprofen, nuroferon, indomethacin and others) increases the risk of side effects listed above and symptoms of overdose. In some cases, patients developed hepatic and renal failure and coma.

With the simultaneous use of acetylsalicylic acid and drugs from the group of antacids, a decrease in the therapeutic effect of aspirin and a slowing of its absorption into the bloodstream are observed.

Tablets of acetylsalicylic acid are forbidden to be taken simultaneously with anticoagulants due to a sharp increase in the likelihood of massive internal bleeding and a strong dilution of blood.

With the parallel use of acetylsalicylic acid with diuretics, their therapeutic efficacy is reduced.

The simultaneous use of this drug with ethanol can lead to poisoning and intoxication of the body.

Storage and dispensing conditions

Tablets of acetylsalicylic acid are dispensed in pharmacies without a prescription. The drug should be stored for 4 years from the date of manufacture indicated on the package. After this period, tablets should not be taken orally.

Packaging should be kept away from direct sunlight out of the reach of children.

Acetylsalicylic acid analogues

Structural analogues of the active substance: Aspicor, Aspirin, Aspirin Cardio, Accecardol, Acetylsalicylic acid, Cardiasc, Cardiomagnil, Colfarith, Mycristin, Plolidol 100, Plolidol 300, Polokard, Taspir, Trombo ACC, Trombogard 100, Trombopol, Upsarin UPA.

Acetylsalicylic acid price

Acetylsalicylic acid tablets 500mg - from 7 rubles.

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